Entrez gene ID | | 117159 |
Official gene symbol | | DCD |
Full name | | dermcidin |
Aliases | | ,AIDD,DCD-1,DSEP,HCAP,MGC71930,PIF, |
Gene summary | | This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q13.1 |
Gene position | | 55042149 - 55038375 Map Viewer |
Gene orientation | | minus |
Gene size | | 3775 bp |
Gene sequence |
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OMIM ID | | 606634 |
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