Entrez gene ID | | 120526 |
Official gene symbol | | DNAJC24 |
Full name | | DnaJ (Hsp40) homolog, subfamily C, member 24 |
Aliases | | ,DPH4,JJJ3,ZCSL3, |
Gene summary | | Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM] |
Location | | Chromosome: 11 Locus: 11p13 |
Gene position | | 31391377 - 31454382 Map Viewer |
Gene orientation | | plus |
Gene size | | 63006 bp |
Gene sequence |
| |
OMIM ID | | 611072 |
|