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Gene information for DNAJC24 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID120526
Official gene symbolDNAJC24
Full nameDnaJ (Hsp40) homolog, subfamily C, member 24
Aliases,DPH4,JJJ3,ZCSL3,
Gene summaryDiphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]
LocationChromosome: 11   Locus: 11p13
Gene position31391377 - 31454382  Map Viewer
Gene orientationplus
Gene size63006 bp
Gene sequence
OMIM ID611072