| Entrez gene ID | | 122704 |
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| Official gene symbol | | MRPL52 |
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| Full name | | mitochondrial ribosomal protein L52 |
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| Aliases | | ,-, |
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| Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which has no bacterial homolog. Multiple transcript variants encoding different protein isoforms were identified through sequence analysis. [provided by RefSeq] |
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| Location | | Chromosome: 14 Locus: 14q11.2 |
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| Gene position | | 23299092 - 23304246 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 5155 bp |
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| Gene sequence |
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