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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMB11 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 122706 Official gene symbol PSMB11 Full name proteasome (prosome, macropain) subunit, beta type, 11 Aliases ,BETA5T,FLJ16369, Gene summary Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307), beta-2 (PSMB7; MIM 604030), and beta-5 (PSMB5; MIM 600306). Three additional subunits, beta-1i (PSMB9; MIM 177045), beta-2i (PSMB10; MIM 176847), and beta-5i (PSMB8; MIM 177046), are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007 [PubMed 17540904]).[supplied by OMIM] Location Chromosome: 14   Locus: 14q11.2 Gene position 23511376 - 23513269  Map Viewer Gene orientation plus Gene size 1894 bp Gene sequence >PSMB11:4511376..4513269:Length=1894 ACCAGACCCCAGCCACAAATTCCTGGCTTGCTTCTTCCAAACTTCATTCAGCCCCAGGGA TGGCTCTGCAGGATGTGTGCAAGTGGCAGTCCCCTGACACCCAGGGACCATCACCTCACC TGCCTCGGGCTGGCGGCTGGGCTGTGCCCCGGGGTTGTGACCCTCAAACCTTCCTGCAGA TCCATGGCCCCAGACTGGCCCACGGCACCACCACTCTGGCCTTCCGCTTCCGTCATGGAG TCATTGCTGCAGCTGACACGCGTTCCTCCTGTGGCAGCTATGTGGCGTGTCCAGCCTCAT GCAAGGTCATCCCTGTGCACCAGCACCTCCTGGGTACCACCTCTGGCACCTCTGCCGACT GTGCTACCTGGTATCGGGTATTACAGCGGGAGCTGCGGCTTCGGGAACTGAGGGAGGGTC AGCTGCCCAGTGTGGCCAGTGCTGCCAAGCTCTTGTCAGCCATGATGTCTCAATACCGGG GACTGGATCTCTGTGTGGCCACTGCCCTCTGCGGCTGGGACCGCTCTGGCCCTGAGCTCT TCTACGTCTATAGCGACGGCACCCGCCTGCAGGGGGACATCTTCTCTGTGGGCTCTGGAT CTCCCTATGCCTACGGCGTGCTAGACCGTGGCTATCGCTACGACATGAGCACCCAGGAAG CCTACGCCCTGGCTCGCTGCGCCGTGGCCCACGCCACCCACCGTGATGCCTATTCAGGGG GCTCTGTAGACCTTTTCCACGTGCGGGAGAGTGGATGGGAGCATGTGTCACGCAGTGATG CCTGTGTGCTGTACGTGGAGTTACAGAAGCTCCTGGAGCCGGAGCCAGAGGAGGATGCCA GCCATGCCCATCCTGAGCCTGCCACTGCCCACAGAGCTGCAGAAGATAGAGAGCTCTCTG TGGGGCCAGGGGAGGTGACACCAGGAGACTCCAGGATGCCAGCAGGGACTGAGACGGTGT GAGAAGCAGGACTTGGTTGGGGATGGTGTAGGCCTGGGGAGTGGGTGGGAGGATGGGCAG CAGGGGGAGGGTCCCGCTGGCAGCAGCCTCACAGCGTCTGGCTCTAGCCTGTATGGGTTG CTGGCTTCATTTATTGCAAGTCTCCATCCTTTCATGACTCCCAGAGCTATTATGGCTCTG CCCAACAAGTTCCTATTGACTCCCAGTGGATTGGTCCAGCCTCCTTCTTGGCACCAAGTC CGTCTTTCATTCAACACTTGCAGTGTGCCTACTGCATGCCAGACGCATGCTAGGTGCTAG ACCCTCTTTTCTTGCCATCTTCTCTGCTTTTTTCCATCATCTCATCCCCAGTTTCTCTTA GTTTCGGTCCTTTATGTGTCTCAGCTTCAGCGTCTTTGTCTTTTTCTCCTGATCACTTTG TCAGCATGGTAAGATGGGGCACCCGGGAAGGGAGCAGCCCCTCTCAGAACGAGGCGTAGT GATAGACACCCTTTGGATGGTGATGGGCTTGTCTTATCTGCTCTCCTTCTCTGACTTGAC CATCATGACTAGAATGATTATCCCTTTACTGAATGCAGTTCTCATCGCAACCCTTTGAGG TAAAAATGAGTCTCTCTTTACAGAAGAGGAATCAGGTTCAAAGGGTTATGTGGCTTGCCA GGGTCACACAGTAAGTGGCAGGGATGACACTTAGATCCAGGCCTTCTCCTCCAGGGTCCA TGCTCTTTCAGCACAGCTCCCCCTCCCAGGCCCTCTGCCCTGCCTTTCCTCTCTTCCCTG CAGGCTTCCGGAGAGGGATGTGGAGGGAGAAAGTAGCTAGGCCAGTCCCCTGCCTGGTGG CTCATGTGGCTTTATCTTCCAGGCCTGGAGCCATCCCCCACAGCCCACCCTTGCTCTCCA GCTTTCTGGGCCTGGCGGTGCCGCTGCCAGACTT OMIM ID 611137