Entrez gene ID | | 12290 |
Official gene symbol | | Cacna1e |
Full name | | calcium channel, voltage-dependent, R type, alpha 1E subunit |
Aliases | | A430040I15,BII,Cach6,Cacnl1a6,Cav2.3,Cchra1,alpha1E |
Gene summary | | This gene encodes an integral membrane protein that belongs to the calcium channel alpha-1 subunits family. Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes. Voltage-dependent calcium channels are multi-subunit complexes, comprised of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The isoform alpha-1E gives rise to R-type calcium currents and belongs to the high-voltage activated group. Calcium channels containing the alpha-1E subunit may be involved in the modulation of neuronal firing patterns, an important component of information processing. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1 G3|1 86.0 cM |
Gene position | | 156573050 - 156239649 Map Viewer |
Gene orientation | | minus |
Gene size | | 333402 bp |
Gene sequence |
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