Entrez gene ID | | 1236 |
Official gene symbol | | CCR7 |
Full name | | chemokine (C-C motif) receptor 7 |
Aliases | | ,BLR2,CD197,CDw197,CMKBR7,EBI1, |
Gene summary | | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q12-q21.2 |
Gene position | | 38721736 - 38710021 Map Viewer |
Gene orientation | | minus |
Gene size | | 11716 bp |
Gene sequence |
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OMIM ID | | 600242 |