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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CCR8 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1237 Official gene symbol CCR8 Full name chemokine (C-C motif) receptor 8 Aliases ,CDw198,CKR-L1,CKRL1,CMKBR8,CMKBRL2,CY6,GPR-CY6,MGC129966,MGC129973,TER1, Gene summary This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq] Location Chromosome: 3   Locus: 3p22 Gene position 39371197 - 39375171  Map Viewer Gene orientation plus Gene size 3975 bp Gene sequence >CCR8:39311197..39315171:Length=3975 TTTGTAGTGGGAGGATACCTCCAGAGAGGCTGCTGCTCATTGAGCTGCACTCACATGAGG ATACAGACTTTGTGAAGAAGGAATTGGCAACACTGAAACCTCCAGAACAAAGGCTGTCAC TAAGGTATGTGCTACAAGCATCCTTGGGGAAGAAGGGCATGAGTAGGCAGGGGCATTTTT ATATCTTTAGAGGATAGGCAAAGGGAAGACCAAAATTTCAGAGGTCTAGCACAAGAAGTA AAATTTTTTTTTAAATCTTTGCATTTCCTCAGAGCCCACAAACATGCATGTGTCTTAGTG GCTGCCCATGCTCTGGCTGAGGAGAGCAAACCGTGCCATATTCTCTGCAGGCCTTTAGGA GAGAGTGAAAACTCCTACAAGAGTGGGAAGGTAGATAAGAGAAGATCCTTTATAATACCA GGCATCTGGGAAGATCTGTCCTTGTGCTGGGTACAGGGCTTCTATCAGGTAACTGAAGGA CACCTGGGTGCTGTTCTTAAGGAAAGAAGCCAGCGAGCAAACTTTCATATGACTAAAGAA GTTGCTGGTGGGTGCCTGTAGTCCCAGCTACTCAAGAGCCTGGGGCAGAAGGATTGCTTG CGCCCAGAAGTCAGGGCTTTGTGTGAGATCACACCTGCGTATAACTACTGTACTCCAGCT TGGGCAACATAGTGAGACCCTGTCTCTAAAAAAATAAATAAATTGCTTGCTTGCTTGCTT GTGCTTTCAAATCATAGAAAAGTAGCAGAGTGGAGAGGGGTGTCTGAATGTAAAGCAAAC AAATGCCTTGGAAAAATATGTCTGGATTGAAATTGCATTGAATGTATATATCAATTTGAG AAGAATTGTCAAGTTTTATAATTTTTATGTAACTGAATTGCATTTTTATTAGTTTTATTC CTAGTAATGCTAGTAATTTTCATTGCTAGTATAATTGGGATCATTTTTCTATTGCATTTA TAAAGTTATTTTTTTTCTGGTGCTTAGGAAAGCAATTAAAAGAATAAACTGATGAATATC ATGCAGATATATCTCTAAAACAATAAGCAAAATACAAAGGGAAAAACAATATATCATTTA TGTAAGTTAAAACAATATATCATTTATGTAAGTTAAAACACACAAAAATATATATTGTTT ATGGATATATATAAATATGTAAAAGTACAGGGGGAAATTGTTTGGAATGATACATACCAA ATTGGTTTTAGTTGTTGTTTCTGTTATGGGGATAAGTTGTGTAGTTAAAGGGAACATTAG CTTCATCTCTATTGCATCAGAAATAAAAAAAGAAAGAGGGATGGAAGGAAGAGAGGGAAT GAGGGAGGGAGAAAAGAAGGGAGAAAAAAAGAAGGAAGGAAGGAAAAAAAAATAACCCAA AGCATTGTGAGAATATGTTAGCAGCTGCTAATTCTAGGTGATGGAACTATGGGTATTTAC ATTTTCTTTGTAAGTTTTGGCTTTTCTCATCTCAGCTGACTCCCTTTGGTTTACATAACA AAATACAATAGACTGAGTGGCTTAAACAACAGAAAGTGTTGTTTAACATACTTCTAAAGG CTGGAAGTCCAAGACCAAGCTGCCAATGCAGTTGATTTCTGGTGAGGCTTCTCTACCTGG CTTGCTGATTTCAGCCTTCTTGCTGTGTCCTCACATGGTCTTTACTCCATGCACAAGGGG AGCAAAATTTCTTGTGTCTCTTTCTCTTCTGTTAAGGACACTAGTTCTATCAGATTAGGG CCCTGCCTTTTTTGGTTTTGTTTCTGTTTTCTTTTTTTTGAGACAGAGTCTCACTCTGTC ACCCAGGCTGGAGTACAGTGGCTTGATCTCGAGTCATTGCAACCCCTGCTTCCTGGGTTC AAGAAATTGTCGTGCCTCAGCCTCCCGAGGTAGCTTGGATTACAGGCATGTGGCACCATG CCTGGCTAATTTTTGTAATTTTAGTAGAGACGGGGTTTTGCACTGTTGGCCAGGCTTGTC TCGAACTCCTGGCCTCAAGCAATCCGCCTACCTTGGCCTCCCAAAGTGCTGGGATTACAG GTGTGAGTCACTGTGAGAGCCAGGGCCCTGCCTTTATAACCTCATTTAACCTTTTTTTTT TTTTTTTAATTTTAATTTTTTTTTTTTTTTTTGAGACAGAATCTCACTCTGTCGCCCAGG ATGGAGTGCAGTGGTGTGATCTCGGCTCACAGCAACCTCCACCTCTTCGGTTCAAGTGAT TCTTCTGCCTCAGCCTCCTGAGTAGCTAGGATTACAGGCATGCACCCGCCATGCCCGGCT AATTTTTGTATTTTTAGTAGAGACGGGGTTTCGCCATGTTGGCAAGGCTGGTCTTGAACC CCTGACCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTAGGATTACAGGCATGAG CCACAGCTCCCGGTCTATCATTTAACCTTAATTACATCTTTAAAGGCCCAAATAGTCTCA CCCACTCCAAATAGTCACACCCACACCGGAGGTTGAGCACTTCAACACATGAATTTGGGG AGGACACAGTTCAGTCCATAACATCCCCCTAATTTTTAAAAAATAAAAATGTTTTTAAGG AGTGAATGTCTTTTATGTGTCTCTGTGACCAGGTCCCGCTGCCTTGATGGATTATACACT TGACCTCAGTGTGACAACAGTGACCGACTACTACTACCCTGATATCTTCTCAAGCCCCTG TGATGCGGAACTTATTCAGACAAATGGCAAGTTGCTCCTTGCTGTCTTTTATTGCCTCCT GTTTGTATTCAGTCTTCTGGGAAACAGCCTGGTCATCCTGGTCCTTGTGGTCTGCAAGAA GCTGAGGAGCATCACAGATGTATACCTCTTGAACCTGGCCCTGTCTGACCTGCTTTTTGT CTTCTCCTTCCCCTTTCAGACCTACTATCTGCTGGACCAGTGGGTGTTTGGGACTGTAAT GTGCAAAGTGGTGTCTGGCTTTTATTACATTGGCTTCTACAGCAGCATGTTTTTCATCAC CCTCATGAGTGTGGACAGGTACCTGGCTGTTGTCCATGCCGTGTATGCCCTAAAGGTGAG GACGATCAGGATGGGCACAACGCTGTGCCTGGCAGTATGGCTAACCGCCATTATGGCTAC CATCCCATTGCTAGTGTTTTACCAAGTGGCCTCTGAAGATGGTGTTCTACAGTGTTATTC ATTTTACAATCAACAGACTTTGAAGTGGAAGATCTTCACCAACTTCAAAATGAACATTTT AGGCTTGTTGATCCCATTCACCATCTTTATGTTCTGCTACATTAAAATCCTGCACCAGCT GAAGAGGTGTCAAAACCACAACAAGACCAAGGCCATCAGGTTGGTGCTCATTGTGGTCAT TGCATCTTTACTTTTCTGGGTCCCATTCAACGTGGTTCTTTTCCTCACTTCCTTGCACAG TATGCACATCTTGGATGGATGTAGCATAAGCCAACAGCTGACTTATGCCACCCATGTCAC AGAAATCATTTCCTTTACTCACTGCTGTGTGAACCCTGTTATCTATGCTTTTGTTGGGGA GAAGTTCAAGAAACACCTCTCAGAAATATTTCAGAAAAGTTGCAGCCAAATCTTCAACTA CCTAGGAAGACAAATGCCTAGGGAGAGCTGTGAAAAGTCATCATCCTGCCAGCAGCACTC CTCCCGTTCCTCCAGCGTAGACTACATTTTGTGAGGATCAATGAAGACTAAATATAAAAA ACATTTTCTTGAATGGCATGCTAGTAGCAGTGAGCAAAGGTGTGGGTGTGAAAGGTTTCC AAAAAAAGTTCAGCATGAAGGATGCCATATATGTTGTTGCCAACACTTGGAACACAATGA CTAAAGACATAGTTGTGCATGCCTGGCACAACATCAAGCCTGTGATTGTGTTTATTGATG ATGTTGAACAAGTGGTAACTTTAAAGGATTCTGTATGCCAAGTGAAAAAAAAAGATGTCT GACCTCCTTACATAT OMIM ID 601834