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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACKR2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1238
Official gene symbolACKR2
Full namechemokine binding protein 2
Aliases,CCBP2,CCR10,CCR9,CMKBR9,D6,hD6,
Gene summaryThis gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p21.3
Gene position42850964 - 42908775  Map Viewer
Gene orientationplus
Gene size57812 bp
Gene sequence
OMIM ID602648