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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACER1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 125981 Official gene symbol ACER1 Full name alkaline ceramidase 1 Aliases ,ASAH3,MGC138327,MGC138329, Gene summary Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM] Location Chromosome: 19   Locus: 19p13.3 Gene position 6333640 - 6306510  Map Viewer Gene orientation minus Gene size 27131 bp Gene sequence >ACER1:complement(6246510..6273640):Length=27131 CCTCATCAGGGCCCAGCCTTCCCAAGCTCGCCTTCTCTCTGCCGGGCGCAGCCGGCTGGT GGTGGCCACTGAGACAAGATGCCTAGCATCTTCGCCTATCAGAGCTCCGAGGTGGACTGG TGTGAGAGCAACTTCCAGTACTCGGAGCTGGTGGCCGAGTTCTACAACACGGTGAGTGCG TGGGTGTGTGAAGGAGTCTCGCCAGATGCCGGTTCGAATCCCGGTTCCTCCCCATACAGC CTTACTGGGGAATCTTGCTGGAGTGGTTCACCTGTCTCAGCCCTAGTTTTCTCATCTGTT AGCCAAAGAGTGCCAGCTTTCATTCATTTACTTGTCTTTACTTGATGCCAAGCTCTGTGG TAGGTTTTGGAGACACATTGGTGGCCAGGAAAAGAACCGGTCTCTGCCTTCCCTAAGCTA ACTCTGATGTGACTGCAGGCATTTGCAACCGGGAGCGATGGTGCCTTCTTGGAGGGCACA GAGGCAGCTGTGGTAGGGGGAGGCAGAGGGTGCCCCTGAGCTAGAGGGGGTGGGCCAATC AGGAAAGGCTTCCTGGAAGAGGTGATTGTGTCTGTCTTGTTTGCAGCTGTACCCACTGAC CAACTTGTCCCAGTGTGCCTGGGACTATCCTGGTTTCAGTATTTAAAAAGTTTCACCTCT TGGCTGGGCGCGGTGGCTCACGTCTGTAATCCTAGCACTTTGGAAGGCCAAGGTGGGTGG ATTGCCTGAGCTCAGGAGTTGGAGATCGCCCTGGGCAACGTGGTGAAAGCCCATCTCTAC TAAAATAAAAAATTAGCTGGGTACGGTGTCAGGCATCTGTAGTCCAAGCTACTCAGGAGG CTACGGCATGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCTGAGATTGTGC CACTGCACTCCAGCCTGGGTGAAAAAGCGAGACTGTCTCAAAAAAAGAAGAAAAAAAGTC CCACCTCCTGAGAAACTCCTCAGTTCTGGACATTCTGAGGTGGTCTTCTCTTTCCCTGTT AAAACACCACATGGGAAGTGCTAAAAAATCATGGATGTACCTAGCACCATGGCTCATGCC TGTAACCCCAGCAATTTGGAACGCAGAGGCAGGAAGATCGCTTGAGCCCAGGAGTTCCAG ACCAGCCTGGGCAACATAGCAAGACCCTGTCTCTACAAAAAGTTTTTAAAAATTAGCTGG GTGTGGTGGTGTGTGCTTGTAGTTCCAGCTACTTGGGAGGCTGAGGGGGGAGGATTTCTT GAACCCAAGAAGTGGAGGATGCAGTGAGCTGAGGTCATACCACTGCACTCCAGCCTGGGT GACAGAGGGAGACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAGGCCGGGCGCGGAGGCT CACGCCTGTAATCACAGCACTTTGCGAGGCCAAGGTGAGTGGATCACCTGAGGTCAGGAG TTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAG CCAGGTTTGGTGGCAGGCACCTGTAATCCCAGCTGCTTGGGAGGCTGAGGCAAGAGAATG GCTTGAACCCAGGAGGCGGAGGTTTCAATGAGCCGAGATCGCACCATTGCACTCCAGCCT GAGGGACAAGAGCGAGACTTCGTCTCAAAAAAAAAAAAAAAAATAGGAATGCACAAATGA TCACGGCATTTAGCCAAAGCTTAAAGCCAAAGATCAGTGCAGCTATGCCATGCCCATACT GGGTGCTGGGAACACAGAGGTGTTTGCCTGGAGCCCTGGGAATGATGGGATCCAGGCATA GTGCTTAGTTCTTTTGTTTGTTTGTTTGTTTGTTTTGAAACGGAGTCTCGCTTTGTCACC TAGGCTGGAATGTAATGGCGCGATCTCGGCTCACTGCAACCTCTGCCTCCCGCGTTCAAG CCATTCTGCTGCCTCAGCTTCCCGAGTAGTTGGGATAACAGGTTCCCACCACCACGCCTG GCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGA ACTCCCGACCTCAGGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGT GAGCCACGGCGCCCGGCCTCGTAGTGCTTAGTTCTATGCCCTGCACATAGGCCTTGCTCA GTGAGCAGAAGAGTGCTTGCTGGCTGGGTGCTATGGCTCACGCCTGTAATCCCAGCACTT TGGGAGGCCGAGGGGGGTGGATCATGAGGTCAAGAGGTCAAGACCATCCTGGCCAACGTG GTGAAATGCCGTCTGTGCTAAAAATACAAAAAATTAGCCAGGCATGGTGCCGGGCGCCTG TAGTCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGT TGCAGTGAGCCAAGATTGTGTCACTGCACTCCAGCCTGGTGACAGAGCGAGACCTCATCT CAAAAAAAAAAAAAAAGTGCTTGCTGTGTACCAGGCATGACCCTAAACATTTTACGTGAA ACACCTCCTTTAATCTGCACAGTGACATGGGGAGTTAGATGCAATCTATATGATACAGAC TTCATCCCATTTTCCAGGTGATAAAACAGGTGTTCAAGGAGTTTGAAGGCTGTGCCCAGG GTCACCCTGGTTATTAGAGCCAGGATTTAAACTTGGTGAGTCCAGGAGACTTTTCTGGGA GGAGAGTCCGAGGCTCAGGTTGCTCTGACCCTGTTGCCTTTCACCCCGGGGCTTCCCATA CCTGGGAAGTGGGATTATGAGACTCCAGGATCCTCACGGTCTCACTGATTCTTGCTCTTC CTTAGCCAGAGATATGGTTCCCGGTCCTCAGTAGTCCCACCTCTAACATGGGAGGGAGCT GAATGATTGGTCCTACGAGGCTGAGATGATGGGTAAGGGCTCTAGAGCTCTTCTCTCTGG AATCCCCAGCAGCCACTGTGGTCCAGTGTTCTGTTTTCATCCTGCACCCAGATGAGAGCC CTTGCAGAAGGCACTGAGAGGCTGGGTATGGTGGCTCTCACCTTTAATCCTAGTACTTTG GAAGGTCGAGACAGGAGGATCACTTGAGGCCAGAAGTTCAAGACCAGCCTAAGCAACATA GCAAGACCCAGTCCCTACACAAAATTTAAAAACTAGCTGTGGGCTGGGCACCACTGGCTT ATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTAGATCATTTGAGGTCAGGAAT TTGAGACCAGCCTGGACAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGC TGGGCATGGTGGCGCATGCCTATAATCCCTGCTACTGGGGAGGCTGAGGCACGACAATCA CTTGAATCTGGGAGGTGGAGGTTGCAGTGAGCCGAGATCACGCCATTGCACTCCAGCCTG GGTGACAGAGCAAGACTCCATCTCAAAAGATTAAAAATTAGCCGGGCGTGGTGGCTCACG CCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACGAGGTCAAGAAATCGAG ACCATCCTGGCTAACACGGTGAAACCCCGTCTCTGCTAAAAATACAAAAAAATTAGCTGG GCGTGGTGGCGGGCGCCTGTGGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTATGT GAACCCGGTAGGTGGAACTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAACCTGGGT GACAGAGCAAGACTCCATCTCAAAAAAAAAAAAATTAAAAATTAAAAAATTAAAAATAAA ATAAAAATAAAAACTAGCTGGTAGGCTAAGGCAGGAGGATTGCTTGAGTTCAGGAGTTTG AAGCTGCAGTAACCTGTTACTGCACCACCGTATTCCGGCCTGGGCAACAGAGTAATATCC TGTCTCTAAAAAATAAAAAGCACCTAGAAAGGGCTGATTCAAGTGTGTCCTGAGCCTGAG TATAGCTGTGTGTTCTTATCTCAGGCAAAATTGTCCTCCACTGGATTCTGCTGTAGCCTG TCCCCAGATAAAATAAATTGAGCCACCTGTAGCTACCGGGTAAGGCTGCAGTTGTCAAAC TCCTCTGATCAGAACACCTATTATGAAAGAAATTTTACATCATCATCATCCTGTACCTGC CTTTCCAGATGTGTATCATACAGAAACAAAAGTTGCACAAAACGAGACTTACCCTTCCCT GGTACAAACACACCTGGATCTATTCTATTCTATTCTATTCTATTCTATTCTATTCTATTC TATTCTATTCTATATCAAAAAGCCTCTCTCCAAACAGGTCAGGGGATGAGGAATAGAATC AGAGTTATGTGAGAAAGGGCTTCCCCAAGACCTTCTCCTCCAAAACGCTTCTGAGTATCC CAAACCCATAGCTAATAAATCATACAGTTCAAAAGGGTGGAGTGGGTGGCAAATTTTTTC TTTTCGTGTTTATTTTATTTTATTTTTATTTTACCTGTTTTAGAGACACAGTCTCACTCT ATTGCCCAGCCTGGGATGGAGTGGTGCCATCATAGCTCACTGCAGCCTTGACCTCCTGGA CTTAAGTGATCCTCCTGCCCCAGCCTTCAAAGTAGCTGGAACCACAAGAGCATGCCACCA AACACAGCTAATTTTTAAATTTTTATACAGATGGGTGCTGGGCACAGTGGCTCACACATG TAATCCCAGCACTTTGGAAGGCCGAGGTGGGCCAATCACTTGCGCTCAGGAGTTCAAGAC CAGCCTGGAAAACACGATGAAACCCCATCTCTATCAAAATTACAAAAAAAAAAAAATTAG CCAGGCATGGTGGCATGCATCCGTAGTTCCAGCTACTTGGAAGACTGAGGCAGGAGAATT GCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGTGGAGATGGTGCCACTGCACTCCAGCCT GTGCGAAAGAGTGAGACTCTGTCTAAAAAAACATTGTTTTGTATAGAGATGGGGTCTTGC TATGCTGCCAGGCTGGGCTCAAGTAATCCTTGTGCCTTCACTTCCCAAAGTGATAGGATT ACAGACATAAGCCACTGCACCCAGGGCCAACCTTTTCTGTACAGGGCTAGCTAGTAAATA TTTTTGACTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCAGTCTGTTGCCCAG GCTGGAGTGCACTGGTACAATCTCGATCTTGGCTCACTGCAACCTCCACCTCCCTGGTTC AAGCAATTTTCCTGTCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACCTGCCACCACTC CCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCTTGTTGCTCAGGCTGGTCT TGAACTCCTGACCTCAGGTGATCCACCCTCCTTGGCCTCCCAAAGTACTGGGATTACAGC CATGAGCCACCACGCCTGGCCAATATTTTTGGCTTTCTGGGCCATCCAGACTCTGTCTCA ACTACGCAACTATGCCACTGTAGCTGAAAACCAGCCATAGATAATAGATAAATAAATGGG TGTGGCTGTATGCCAATAATTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCGCCCA GGCTGGAGTGCAGTGGTGCAATCTTGGCTCACCACAACCTCTGCCTCCCAGGTTCAAGCA ATTCTCCTGTCTCAACCTCCCGAGTAGCTGGGATTATAGATGAGCACCACCATGCCCAGC TATTTTTTGTTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAA CCCCTGACCTCGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCACAAG CCACCGTGCCTGGCCAATTTTTTTTTTATTGACACTGAAATGTGCATTTCATATAATTTT CACATGTCACAAAATAATCTTTTAATTTTTCAATCATTTGAAAATGTAAACATGATTCTT AGCTTGTGGGACACATGATACAAGGCAGTGGGCTGAACTTTGCCCACAGGCCAAAGAGTG TTTATTTATTTTATTTTATTTTATTTTATTTTTATTTTATTATTATTTATTTATTTATTT ATTTTGAGACGGAGTCTCGCTCTGCCGCCCAGGCTGGAGTGCAGTGGCCTGATCTCGGCT CACTGCAAGCTCCGCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCT GGGACTACAGACGCCCGTCACCACCCCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGG GTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTTGTGATCCGCCTGCCTCAG CCTCCCAAAGTGCTGGGATTATAGGTGTGCACCACCATCCCCAGCTAATTTTTGTATTTT TTGCAGAGACAGGGTTTCACCAGGTCATCCAGGTTGCTCTCAAACTCCTGACCTCAGGCG ATCTGCCTGCCTCAATCTCTAAAAGTGCTGGCATTATAGGCATGAGCCACTGCACCCAGC CTGCTTTCTTGCTGCTCTGTTTGGGAGCATGCAGAGCCCAGCAGCTCATGGTCAGGGTTA CAGAAACAGGAAACACCCAAGAACTCACCCCAGGTGTTTGGAGACTTCATAGAAAAGGAC ATGTAGGAGTTGGGTTTTGAAAGATGAATAGGAGTTTGCCAAGTGGGGAAGGATAGCAGG AGAGCAGGGAAAGATGTGCTCAGTTCTGGAAGTCAAAGAAGAGCTGGTCAGATTGAGAAA GGAGAAAGTATGTTCCTGTAGCTACAATGTGGGGAGAGATGAAGACGTAACGGTTCGCAT GCTTGGTTAGAATGTTGGAAACGTATCCTGTGTTCACTGATGGACTCATTCATTTATTCA ATCAAAATGCTATAAACCCACCGCTGCTGGATGATCCTGGGATTCCAGGGAGGAGGCTCG GTGTCCCCAGGTTGTAAGAGACCCAGAATTAGAAACAGATTTCTTCAGCCCCATGGTTAG CTTGAGGCGGAGAGAGGAAGGGGGTGCCAGAAACGGGGTGTCAGAGGAATGGGGCATAAG GTCTCTGCTTGCTGAATGGGGAAAGAACATCAACAATGCTCTGGGGGGCAAGTGTGGTGG CTTACACCTGTAACCCCAGCACTTTAGGAGGCCGAGGCAGGAGGATCACTTGAGCTCAGG AGTTTCAGACCAGCCTGGGCAATATAGCAAGACCCCATCACTACAAAAGATTAAAAAAAA AATAGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAACACCTTGGGAGGCCGAGGCCGG CGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTA CTAAAAATATAAAAATTAGCCGGGCATTGTGGTGGGCGCCTGTGGTCCCAGCTACTCGGG AGGCTGAGGCAGGAGAGTGGCGGGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGAT GGTGCCACTGCACTCCAGCCTGGGCTACAGAGCGAGACTCCGTCTTTAAAAAAAAAAAAA AAAAAAAAATAGCTGAGCATGGTGGTGCACACTTGTGGTCCCAGCTACTCCGGAGGCTGA GGCAGAAGAATCGCTTGAGCCCAGGAGTTCAAGGCTGCAGTGAGCTATGATCACACCACT TCACTCCAGCCTGAGGGACAAAACCAGACCCTGCCTCAAAATAAAACAAAAACAAAAACA ACAATGAAAAACAAACAATACCATGGAAACCAAATCTAAAAAGAATGAGTAGATGTCCTC TAAGGCTTTGAATTTTGTTTGTTTGTTTTAGTGACAGGGTCTTGCTCTGTTGCCCTGCCT GGAGTACAGCGGTGTGATCATAGCTCACTGCAGCCTTGAACTCCTGGGCTCCAGCAGTCC TCCCGTCTCAGCCCCCAGAGTAGCTGGGATTACAGGCATGAGCCACCACGCCCAGCTCAA GGGTTTGGAGGCAAAGGGAATAGCATATGTAAAGGTCTTTGTTGTTGTTCTTGTTTTGAG GCGGAGTCTGGCTTTGTCACCCAGGCTGTAGTGCAGTGGCACGATCTTGGCTCACTGCAA CCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTAT AGCACCTGCCACCATGGCTGGCTAATTTTTTGTATTTTTAATAGAGACAGGGTTTCACTT TGTTGGTCAGCCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCACCTCAGCCTCCCA AAGTGCTGGGATAACAGGCGTGAGCCACTGCACCCGGCCAAGGTCTTGAGGTGGAACAGC ACAGCCTGGCAGGAAATAGTGAGCAGCTTGAAGCGGAGCCCAGGGGGAGTCTCCCCAGTC GATGGGGGAGAGACTGAAGGGTGAGAGAAAGGACTGGAAAGGTTTTCAGGGGCCAAATTG GGAATGTCAGGCTGAGGACTGTGTGCTCTGTCCTGAGAGCCCTGGGGAGCCATGGGGTGG CTTTTGAACAGAGGAGAGTCATGATGTGGGGTCAGCTGGGGCAACCGGTGGCATTTGGCA GATGGGCAGAGAGAGCCAGGAAGGGTCATCCAACAGGAACAGAAGTCAGCAGTGTGGGAG GGGCGGCTCGAGTAGGGAAGGGGAAGAGGTCCAGGTGTGGGCTCCGTCAGTTTGCTCCTG CTTGCATTGGCCTGGTGGCCTCCAGGTGCAGCCTTCTTCTGGGTTGATGACAACTTAGGA GAGTTTCCTTCCTTCCTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCTTCCT TCCTTCCTTTCTCTCTCTCTCTTTCCTTCCTTCCTTCCTTCCTTTCCTTCTCTCCTTCTT TCTCTTTCTTTCTTCTCTCTTCTCTCTCTTTCTCTTTCTTTCTTTATTTTATTTTGTTTT GAGATGGAGTTTCGCTCTTGTTGCCCAGACTAAAGTGCAACAGTGCAATCTCTGCCTCCC GGGTTCAAGAAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGAATTACAGGCACGTGCCA CCACGCCCGGTTAATTTTGTATTTTTTTTTTTTTAGTAGAGATGGGGTTTCTCCATGTTG GTCAGGTTGGTCTTGAACTCCCGACCTCAGGTGATCTGCCCGCCTCGGCCTCCCAAAGTG CTGGGATTACAGGCATGAGCCACCTCGCCTGGCAGAGAGTTTCAAATGGTGCAGGTGGAA GTTTCAAGGTCCCCCAGGTCCTGGAGGCAGTGAGTTATGATCACTTCACTGCACTCCAGC CTGGGCAACAGAGTGAGACCCTGTGTCTAAAAAAAAATTAAAAAGAGGCCAAGTGCGGTG GCTCATGCCTGTAATCCCAGCACTGTGGGAGGCCAAGGCAGGGAGATCACTTGAGGTCAG CAGTTCCAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACAAAAAATACAAAAAT AGCCAGGCGTGGTGGCTCACACCTATAATCCCAGCTACTTAGGAGGGTGAGGCAGGAGAA TCGCTTGAAGCTGGGAGGTGGAGATTGCAGTGAGCTGAGATCACACCACTGCACTCCAGC CTGGGTGACACAGCGAGACTTGGTCTCAAAAAATAAAAATAAAAAGAGAGAAATGAGGAG ATCAGAGTCGGAAGGGGGTGGAGGGGAGATAGTCTGCAGTGCTGCCATCTCCAACACTCT CCTCACCTCCTCTCCTGAGTCTCCTTGAGGCTGGCTTCTGCAGTGGGATTCCAGTCCCAG CTCTCCCCTGAATGCTGTGTGACCCAGGAGGAGACCTGCCCCTCTCTGAGCTACACACAA TGGCAGGTCTCATAAGCTCTAAATTACAAGTATGGATGTGAGATCCACTCATGCCTCCCT CTTCTGCTGTCCTTCTTATCAATATCCACAGCAAAAACAATTAATTACTGGACGCCTCTG GTGTGCCAGGCCCTACCAAAAGCAAGATGGGAGGGCAGGAAAATACTTCTCTGTATTAGT TCATTTTCACTCTGCTAATAAAGACTTACCTTTATGTCTGGGCAGTTTGCAAAAGAAGAA AAAGAGACTAGGCAATTTACAAAAGAAAGAAGTTTAATGGACTTACAGTTCCACGTGGCT GGGGAGGCCTCACAATCATGGTGGAAGGCAAGGAGGAGCAAGTCACATCTTACGTGGATG GCAGCAGGCAAAGAGAAAGAGCTTGTGCAGGGAAACTCCCATTTTTTTTTCTTTTTTTCT TTTTTTTTTTTGAGACGGAGTCTCGCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTC TGCTCACTGCAGGCTCTGCCCCCTAGGGTTCACACCATTCTCCTGCCTCAGCCTCCCAAG TAGCTGGGACTACAGGCACCCGCCACCTCGCCCAGCTAATTTTTTGTATTTTTAGTAGAG ATGGGGTTTCACTGTGTTAGCCATGATGGTCTCTATCTCCTGACTTCGTGATCTGCCTGC CTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAACCACTGCGCCCTGCCTGTTTTGTT TTTTGTTTGTTTGTTTTGAGACAGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGG CGTGATCTCCGTTCACCGAAACCTCTGCCTCCCTGGTTCAAGCTATTCTCCTCCCTCAGC CTCCTGAGTAGCTGGGCTTACAGGTGTGCACCACCACACCTGGCTAATTTTTTGTATTTT CAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGTTCTTGAACTCCCGACCTCAGGTG ATCCACCCACCTTGTTCTCCCAAAGTGCTGGGATTACAGGCATTAGCCACCACGCCCGGC TGAAACTCCTGTTTTTAAAACCATGAGATCTCATGAGACTCATTCGCTATTAGGAGAACA GAGCAGGACAGACCCACCCCGATAATTCAATCACACGGGAATTGTGGGAGTTACAATTTA AGATGACATTTGGGTGGGGACACAGCCAAATCATATCATTCTCCAAAGAAGAATCTTTTG CTTTCTTGTTGCTCTGTTTGCAAGGAGCTGAGTCTGGGGTTGAGGTTGCAGAGCCCAGAC ACTCATGGTTGTGGCTACAGGAGAAGAAAACACCCGAGGAGTCAGCCCAGGTGTTGGGAG GCTTCATGGAAAAGGGCACCCAGGGTTGGGTTTTGAAAGATGAATAGGAGTTTGCCAAGT GGGGTAGGAGTTTGGGGAAAGACAGCAGAAGAGAAGAAGAAGATGTGCTCGAGTCCTGGA AGTCAAATAGGAGCTGCTACATATTTCTGCTACATATTTTGTCTTTCATTTACATCTTTA GATCAAAAGCATCCTTTTAAATAGCTGCATAATATTTCACTAGAATGTATTCAGCCCCAC GCACCTGGGTGACAGTGTTACAGTTTCTATTTTATTTATTCATTTTTTATTGCAATTACA AATGACTTAGGGATGAATTTGTATATAAATCTTGTTGACCCAGGGAAGGCAGATGCCGTA AGTTGGATAATTACATGCATGAAACCAGTGATCTAGCCCATGATACTCCCAGGCAAGATA GGTTCCTCTGGACCTCCTTTCTCCTTTGAAGAAAACAGGTGTTGGTGACCCTTCCCTGCA AGCATCCTGGGGCTGATGGAGGGGTTTGAGTTGTTGGGACAACAATTTCTTCTTTATTCA ACAAGAATTGCAGGAGCACCAGGCTCTGCTCCAGGCTCTGAGGACACAGCAGTGATCCAA GCACCAAAACTCCCTGCCGGCCGGGTGCAGTGGCTCATACCTGTCATCCCAGTACTTTGG GAGGCCGTGGTGGGCAGATGACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGG TGAAACCCCGTCTCTACTAAAAATAATTTTAAAAATTAACCAGATGTGGTGGCACGTGTC TGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGAAGAATCGCTTGAACCCAGAAGGCGGAG GTTGCAGTGAGCTGAGATTGCGCACTGAACCCCAGCCTGGGCAACAGAGTGAGACTCTGT CTCAAACAAAACAAAACAAAACAAACAAAGAAAAAAATACAAGAAACTCCTTGCCCTGGT GGGGCTGATGTTCTGGGGATGGAGAAGAAGAAAATAAGCCAAAGTCAAGGCTACAAGATG CCAGGCGGTGGGATGTGCCAAGGAAGAAAAACTCATGCATTCACTCTCTTTTTTTAAAGA ATGTATTTCGGCCAGATGGGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAG ACAGGTGGATCAGTTGAGGCCAGGAGTTCAAGACTAGTCTTGCCAAGATGGCAAAGCCCC ATCTCTACTAAAAATACAAATAAATAAATAGACAAGCATGGTGATGGGCTCCTGTAATCC CAGCTACTCAGGTGGCTGAGGCAGGAGAATCGCTTGAACCCAAGAGGCGGAGGTTGCAGT GAGCCAAGATCATGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTTGGTCTCAAAA AAAAAAAAAGAAAGAAAATTTTCTGGAATTAGCTAGTGTGATGGTTGCATGCCTTATGAA TATACTGAAACCCACTGAATTGCATAGTTTAAAAGAGTGAATTTTATAGTATGTGATTTA TGTCTTGATTTTAAAAATAGGGATGTTAAAAAAAAAAAAACAACCCACAGCTCTTGGCAC ATCCTAAGCACTGAATACATTGTAGCTATTCTTATTACGAGTGAATACAGCACCCAGAGA TGTCAAAGTGACATTCATTAATTTTATTAGGTATTTATTCATTTCATTGAATAATTAGCA CCAACTGTAATCCTCATAAAATCCTATGAAGTAGGTACAATTATGCTCCCCATTTTACAG ATGGGGAAATCAAGGCTCAGAGAGGGTATATTTCTTTCCTAGGGCCACACAGTATGCAAA TTACAATTGCACAAAAGTTGCAGCTTCTTAAAGAGCCTGGTCCTAGAATCTCTCCCTTAA CCATGGTGCTGTGAGACCACTTAATTACTGGTGATTAGGAATTAATTGTGTGCATTTTGG ATGGCACAGCGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATAA CCTGAGGTCAGGAGTTTCAGACCAGCATGGCCAATATAGCGAAACCCCGTCTCTACTAAA AATACAAAAATTAGCCAGGTGTGGTGGCACACACCTGTAGTCCCAGCTACTCAGGAGGCT GAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCGCCG CTACACTCCAGCCTGGGTGACAGAGTGAGATATACGCATTTTAATTCATGCAATTAAGTC TTGTGCTGTGGCCGGTGCACACTTCGTCCCTCCAACATTAGCAGGCACACTTGGAATGAA TGCAGGTGGCTGTCCTCAACTGGAGACAGAGGCCAGGTGTTGCTGGTGGGAGGGAGTTTG AGCTTTGGCAATGAGGACGAAGAATGAGGAGATGTTGGAGATGTATTCAACAAACTTTTC TTTCTTTCCTTTTTTTTTTTTTTTTTTGAGACAGAATCTCTCTCTGTCACAGGGGTTGGA GTGCAATGGTGCGATCTCAGCTCACTGCAGCCTCCACGTTCAAGCGATTCTCCTGTTTCA GCCTCCTGAGTAGCTGGCACTACAGGCATCCACCACCACACCGGCTAATTTTGTATTTTT AGTAAAGACAGGGTTTCTCCATGTCGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGA TCTGCCCACCTCAGCCTTCCAAAGTGCTGGGATTACAGACATGAGCCACTGCGCCTGGCC CCTTCTGTATTATTTATGTGTATTCTTTTCTACTAAAATGTATTAGGCGCCTACTGTGTG CCAGAGAGTGTTCTAGATACAGGGTGGGGAGGGGGCAAAACACACAGAGCTCCCTGGTCC CGTGGCACTTAACTCTGTAATCCTCACAGCAGCCTCTGGAAGTAGGAGCAGGAAAACCAG GCACAGGAGGTCCCCTGCTGTCCTGACTGTATACACCCCGAGAAGGCAGGGACTTTGTTT TCAGACACTGGTATGGTCCTTGAGCACATAGTAGGTACTCAAGGGATGCTTGGACAAATG AATGAATGAATGAATGAACGAATGAATGAAGGAAGGGAGGGAGGTGATGTCACCTGCTGG AGCTGGGACCAAGAAGGTCCAGCTCACTTGTGTCCAGAGTTCAGGACTGGGCTGGCTTTG GATGGGATCCCAGACAGGTGTCTCCCCCGCCTGGCAGAGCCTGGGTGGGATGAGAAGCAG GGAACGTGGGGGCTGAGCCCCGGAAGGCAGGGAGGGAGACCCTGGCATCCAGGCAGTTTC CGATGTTATCGGAAACTCCATTAGTCGGGGTCCCCCATTAGTCAGTATCTCCACCCACAG TCTCTGTCCTCCTTCTGAGCGCTTAGGGACACTGTTGATAACTCCTGGCTGGACTCTGCT GGCCCCTAAGCTTGGAATAACGATACCCATAACAGGCCTGTTATTATTATTATCTCCTTC AACAATAACAACAGCAGCAGCCCCAGCTATTTTTTGAGCTCATACCACATCCTGGGCAAT GCACTTCTGCAATGCCTCATCTTGTGCATGGCCCGCATCAGCCTGCAAGGTACCATTGAT GATGTGTCCTGCTTTTACTGATACAAGCGAAGAGAAACCAAGAGGCATTAGTCACAGGGC CAGGCAGCAGGGGAGCACCCTCTTAATCACCACCACCCGTCTAGTCTTTCCATCTTTGTT TTCTTTTTTTTTTCTTTTTCTTTTTGAGTTGGAGAGAGATGAGTTAGGAATAATTTTATT TTTATTTATTTATTTATTTTTTTTGAAACGGAGTCTTGCTCTGTTGCGCAGGCTGGAGTG CAGTGGCACGATCTCAGCTCACTGCAACCTCCGCCTCCCGGGTTCACGCCATTCTTCTGC CTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCCTGCCACCACACCCAGCTATTTTTTTT TTTTTTTTGTATTTTTAGTAGAGACGGTGTTTCACTGTGTTAGCCAGGATGGTCTCGATC TCGTGACCTCATGATCCGCCTGCCTGAGCTTTCCAAAGTGCTGGAATTACAGGCATGAGC CACTGTGCCTGGCCTATTTTTTATTTTTTATTTATTTTGGGGGGACAGAGTCTCACTATG TCACCCAGGCTGGAATGCAATCGTGTGATCTCAGCTCACTGCAACCTCTGCCTCCCAGGT TCAAGCGATTCTCCTACCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGCGCCACCGC ACCTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGCCAGGCTGGTC TCGAACTCCCGACTTCAGGTGATCGGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAG GCGTGAGCTGTAATCCATGCCCGGCTAATTTTTTGTACTTTTTTTTTGTTTTTTTTAGGA CGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCTGCCCGCC TCACCCTCACAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCCAGCCTGAACATGTT TTAAATGGAGATTTTTAGAGGCTGAGGTGAGTGGATCTGCTTTGTTCAGGAGTTCGAGAC CAGCCTGGGCAATATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGACATACAT GGTGGTGAGTGCCTGTAATCCCTGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAAC CCGGGCGGTGGAGGTTGCAGTGAGCCAAGATTGCCCCACTGGATTCCAGCCTGGGTGATA GAGCAAGACTCTGTCTCAAAAAGAAAAAAAACACAAAAACAAAACTAACAAACAAAAAAC AAAACAACAACAAAAAAAGTTGGAGAGAGATGAGTTATGGAAGGAATTTATACGCCAAGT TTAAGAGTTTAGACTTTATTTATTGAAGGCCCAGACACGTTTTAATGGATGCTTTTGAAT CTGGGAGACTGGTTGGGTCAGTATCTTCAGGCACGCGTTGATATTCAAGGGCTGGTGTTT GGTTGGAGGCAGAGGGAACATTGTGTTTGTTTGGGAGTATGTGTGCATCAGCACAAATGG AGGCAACTGAACTAGGGCCACGGGCTGAGAAGAGGCGCATGGAGGCGTTGGCATGGCCCC TGTCCCATCTGTCCTTGGACCACTGAAGAGAAGCGCTTGCAGTCCAGAACTGTAGTCGTA ATCTGTTTACTGACATTGTCCATTTCATATCAATCACTTGTTTTTCTTTCCACACCTGTC TTAGTTCAGTTTGTGTTGCTATAAAGGAATAACTGGGGCTGGGTGCAGTGGCTCACGCCT GTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTAGATCACTTGAGGTCAGGAGTTTGAAA ACAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAGTTAGCCGGGTA TGGTGGCACGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAA CCCAGGATGCGGAGGTTGCAGTGAACCGAGATTGCACCACTGCACTCCAGCCTGGGTGAC AGAGTGAGACTCCATCTCAGAAAAAAAAAAAAAAAAAAAAAGATGGGGAGGGAAAGAGAC TTGTTTCTGAGCTCATGTGACAGTTTCATGTTTTTCTTTTGTTTGTATAAATTGAAGAAG TACAAGTGCAGTTTTGTTACATGTATGTATTGTGTGGTGGTGAAGTCTGACCTCTTTTTT TTTTTTTTTTGAGAGGGAGTCTCGCTCTGTCGCCCAGACTGGTGTGCAGTGGTGCGATCT CGGCTCATTGCAACCTCTGCCTCCTGGATTCAAGCGATTGTCCTGTCTCAGCCTCTGGAG TAGCTGGGATTATAGGCATGCACCACCATGCTCGGCTAATTTTTTGTATCTTTAGTAGAG GCAAGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCTTGGTCTCATGATCCACTCAC CTCCACCTCCCAAAGTGCTGGGATTACAGGTGCAAGCCACCGCGCCCGGCCCGATATTTG ATTTTCTGTTTCTGAGTTGTTTCACTTAAGATCATGTCCTCCGGTTCCATCCATGTTGCC GCAAAGGCATTTCATTCTTTGTGTGTGTGTGTGAGACAGGGTTTCACTCTGTCACCCAGG TTGGAGTGAAGTGGCACAATCACAGCTCCTGCAGCCTCCAACTCCTGTGCTCAAGCAATC TTTCCTCCTCAGCCTCTCAAGTAGTTAAGACTACAGGCACATGCCAGTATGTTTGGCTAA TTTTCTAAATTTATTTTTTATGGAGGTGGGGTCTCACTATGTTGCCCAGGCTGGTTGCGA ACTCTTGTCCTCAGGCAATTCTCCTGCCTCAGCCTCCCAAATTGCTGGAATCACAGGCAT GAACCATCACACCTGGCCTATTTCATTCTTTTTTCTTTTTTTGAGACGGAGTCTCGTTCT CTCACCCAGGCTGGAGTGCAGTGCAACAATCTCAGCTCACTGCAACCTCTGTCTCCCAGA TTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGACTCACAGGCACACACCACCA TGCCTGGCTAATTCTTGTATTTTTTGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGG TCTCGAATTCCTGACTTCGTGATTTGCCTGTCTCAACCTCCCCAAGTGCTGAGATTACAG GTGTGAGTCACCACACCTGGGCTCATTCTTTTTTTAATGGCTAAATAGTATTCCAGGCCA GGTGTGGTGGCTCATGCCTGTAATCCCAGCAGTTTGGGAGGCCAAGGCGGGTGGATTGCT TGAGTCCTGGAGTTAGAGACCAGCCTGGGCCACATGGCCAAATCCCATCTGTACAAAAAA TACAAAAATTAGGCTGGCCGTGGTGGCTCAAGCCTGTAATCCCAGCACTTTGGGAAGCCG AGGAGGGTGGATCACAGGATCAGGAGATCGAGACCATCCTGACTAACACGGTGAAACTCC GCCTCTACTAAAAATACAAAAAATTAGCCAGGTGTGGCGGCGTGCACCTGTAGTCCCAGC TGCTGGGGAGGCTGAGTCAGGAGAATGGCATGAACCCGGGAGGCGGAGCTTGCAGTGAGC CGAGATCGCGCCACTGTACTCCAGCCTGGGCGACGGAGTGAGACTCTGTCTCAAAAAACA AAACAAAACAAAACAAAAATTAGCTGGACATGGTGGTGCATGCTTGTAGTCCCAGCTACT TGGAGGGCTGAGGTGGGAGGATTACTTGAACCTGGGATGTCGAAGCTGCAGTGACCCATG ATCGTGTCACTGCATTCCAGCCTCGGCAACAGAGAGAGACCCTGTCTCAATAAATAAATA AATAAATAAATAAATATAAATAAATAAGGCCGGGTGCAGTGGCTCACACCTGTAATCCCA GCACTTTGGGAGGCCGAGGCGGGCGGATCATGGGGTCAGGAGATTGAGACCACGGTGAAA CCCCGTCTCTACTAAAACTACAAAAAAATAATTAGCTGGGCGTGGTGGCAGGCACCTGCA GTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCCAGGAGGCGGAGCTTG CAGTGAGCTGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCAATACTCCATCTC AAAAATAAATAAATAAATAAATAAATAAATAAATAAAATTCCATTGTGTATATATACCAC ATCTTCTTTATCCAATCATTGGGTTGATTTCATATCTTCACCTGTGTGAACAGTGCTGCA ATAAACATATGAACGCAGGTATATTTTAGTATAATGATTTCGTTTCCTTTGGGTAGATAC TCAGTAGCGGGATTGCTGGATCAAATGGTAGTCCTAATTTTAGTTCTTTGAAAATTCTGC ATACTGTTTTCCGTAGAGGTTGTACCCATTTACATTTCCACCCATATTATATAAGTATTT GTCATATGAGAGACTTGTCGCGGCTCAGACATATCAGGGAGACACTTTGTGGGGAGTCAA AGTCTGATGTCAGCACGTCGGGGTCTTGAGTCATTTAATTTTGGGTGCAAATGTTCTTGT GACCTTTTTTTTTTTTTTTTGAGGTGAAGTCTTAGTCTGTTGCCCAGGCTGGAGTGCGAT GGCGTGATCTCGGCTCACTACCACCTCTGCCTCCTGAGTTTAAGCAATTCTCCCACCTCA GCCTCCCAAGTAGCTGGGATTACAGGCACCCACCACTACACCCAGCTATTTTTTTGTATT TTAGTAGAGATGGGATTTCACCATGTTGCCCTGGCTGGTTTCAAACTCCTGACCTCAAGT GATCTGCCTGCCTCAGCCTCCCAAAGTGCTAGGATTACAGGTGTGATCCACTGCACCTGG CCAATTTTTGTATTGTTTTACATTATTGTGAAATATATATTCACATATTATATATATATA TATATTCACAATATATATTTACATACTGTTTTGTAGAGTTTCACTATGTTTTTTGGGCTG GCCTTGAACGCCTGACCTCAGGTGATCTACCTGCCTCAGCCTCCCAAAGTGCTGGGATTA CAGGCGTGAGCCACCATGCCCGGCCATCACCTGAAGTTTCATTCACTCATGTGTCTGATG ACTGTATAGGGAAGAATTGAACCACTGGCCCTCCTCTGGCATCTCTCTCCATCTCAGTGT GGTCTCTACACATGGTTTCTCCAGCGTGGTGGCTTCAAGGGTAGCCAGTCTTCTTGTGTG GTGGCCTAGGATCTGGACGTCTTGTCCTATGAGATAGAGAAAGGTGGAAGCCACAGTTCC TTTTATGACCTAACCTCAGAAGTCACACAGTATCATTTCTGCTTCATGCTGTTTGTCAAA AAGGTACTGCATCGTCTTTCCTTGTCTGCAAGGGCAAGGTCAACTCATGACATCCATGGC CACATTTCAGCCCACAGGAAGAGGAAAGGGGGCAAGCTTTCCTTACGTGGTTTTTGAAAG GACTGACCTGGAAGTAGTAGATGTCATTTACATTCTTATCTCATTGGCCAGAGCAGGTCA AAAGGCCACAAGGCCACAGTGAACTGCAGCGAAGGCTGGGAAATGTAGTCTTTCACTGGG TAAGCTGTGTGCCCAGTTCAAACTTGGGAGATACTATTTTTACAGGAAAAGGGGCTGGGT GCAGTGGTTCATACCTGTAATTTCAACACTTTAGGCTATGGTGGGAGGATCACTTGAGGC TGGGAGCTTGCAACCAGCCTGGGTGACATAGTGAGACCCCTTCTCTACAAAAAATAAAAG AAAATTAGCCAGGTGGGGTGGCGGGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCA GGAGGATCCTCTGAGCTCAGCTGATTGAGGCTGCAATGAGCCATGATCCCACCACTGCAC TCCAGCCTGGCAGCAGACAGCAAGATCCTGACTGTAAAATAAATAAATAGAAAAAGTAAA AGAGAAGGAGAATATATATGGAAGTTTAGTGGATAGTCTTTGCCACACTCACTGAATGAA TGAATGAACCAATAACGGATCGAGAAATTGATCTATGGATGACCAGCTGATGGTCAAGAT CAGCTGAAAAGTGGCTAGGTGCGGTGGCTCACACCTGTAATCCCACCACTTTGGGGAGGC CAAGATGGGCGGATCACCTGAGGTCAGGAGTTCAAGAGCAGCCTGGCCAACATGGTGAAA CCCTGTCTCTACCAAAAATATAAAAAATTAGCTGGGCGTGGTGGCACGTGCCTTTAATCC CAGCTACTCGGGAGTCTGAGACAGGAGAATCGCTCGAACCTGGGAGGTGGAGGTTGCAGT GAGCTGAGATGGCACCACTGCGCTCCAGCCTGAGTGACAGAGCAAGACTCCAAGACTCCA TCTAAAAAAAAAAAAAAAAAAAGGGTCGGCTGAAAGGTTGACAGGTGAGTGATTGACAAA TCCTGGGTTGATGCATTGCCTGAAATGCAGCAGGTAACCGACTGGCTGGTGACTGAGTGT CTGGACAGAGGGCAGCCTCCTCCGTCTCCCCTATCTGACGAGCTCCTCCCTATGGCTCTC TCTGCTCCAGTTCTCCAATATCCCCTTCTTCATCTTCGGGCCACTGATGATGCTCCTGAT GCACCCGTATGCCCAGAAGCGCTCCCGCTACATTTACGTTGTCTGGGTCCTCTTCATGAT CATAGGTAGGGAGGTGTGGTTCAGGTCTGTGACAGTCGGGAGGCAGTGGGGGTTTAGGAG GTGGCGGACCCCACTGACCGCCTGCCCTTGCCGCTGCAGGCCTGTTCTCCATGTATTTCC ACATGACGCTCAGCTTCCTGGGCCAGCTGCTGGACGAGATCGCCATCCTGTGGCTCCTGG GCAGTGGCTATAGCATATGGATGCCCCGCTGCTATTTCCCCTCCTTCCTTGGGGGGAACA GGTGGGTCAGGGGCTGGCCATCTGGACAGGGTGGGGTCTGAGTCTTCAGTTGACTCTACA TGAGCTCACCTGAGTCCCCTGGGTCCCCACCCTTGACCCTCTTTGGGGCCCTTGGAATTC CTCCCCTGACCACTTCGGGTTTTCTCCTGACCCTGCCTGACTCACTTGGGCTTCTGGAGA CCCCTCCCCTGAGCTTACCTGGTTTCTTGGAATCCCTCCCTTGATCCTACTTTGATAACC TGGGACTTCCTCCAGAATCTGTTGCAGCCAACAGGAGTTCCAGGACCTCATGTCTACACT TACCTGGGCCTGAGGGACTCCTCCCCGAGCCTCTCACCTGGCGTTCCTGGCATCTTTCAT CTGATCTGCTTAGACCCCCTGGGTCCCTCTCTTGATCTAATTGATCCCCACTCCCACCCT TGACCCCTGTGAAATAATCTCCTTCTCCTTCTACTTTTCCACCTCCTCCTCCTTCTCCTC CTCCTTCTCCTCCTCCTTCTCCTTCTTCTTCTTCTTCTCCTCCTCCTCCTTCTCCTTCTC CTTCTTCTTCTCCGCCTCCTCCTTCTTCTTTTTCTTCCTCCTCCTCCTCCTCCTTCTTCT TCCTTTTTGAGACAGAGTCTCGCTCTGTCACCCACACTGGAGTGCAGTGGTGCGATCTCG GCTCACTGCAGCCTCTGCCTTCAGGGTTCAAGTGATCCTCCTGCCTCAGCCTCCCGAGTA GCTGGGATTACAGGCACCTGCCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACG GTTTCACCATGTTGGCCAGGCTGGTCTCGATCTCCTGATCTCAAGTGATCCACCTGCCTT GGCCTCCCAAAGTGCTGGGATTACAGGCAAGTGAAATTCTCTTCTAACCCGGCTTAACCC ACCTGAGCCCTCCAGGACCCCCCCAGCCCACCCTATTGACCTCTGGGACCCCTGTCATCT TTCCTTTATCCCTACTGGGTCCTGGAGAGCCACTGTCTGACATCTCTTAAATTCACCCGG ACCCAGGGATCCCTCTTCTCAGCCCAGCTGGGATCCCCTGAACTCCTTGCCTGACCTCAC CTGGGCCCTGGAAACCATCACGCTCTCCCAGGCTCCCTGGGACCCTCTTCTCATCCTACT GAGTCCTCCCTGGGATCCCCCTTTAGACGCTGCCTGGGCTCACCTGGGCTCCCTGAGACT TTCTGCTGAGTCCACTTGGGAGCCTCAGGACCTTCTTCTTCTCCTTCTCCTTCTTCTTTT TTTTTTTTTTTTTAGATGAAGTCTCGCTGTGTCCCCCAGGCTGGAGTGCAGTGGCGCAAT CTTAGCTTGCTGCAACCTCCAATTCCCAGGCTCAAGCGATCCCTGCCTCAGCCTCTTTAG TAGCTGAGATTACAGGCACATGCCACCACATCCAGCTAGTTTTTTGTATTTTTGGTAGAG ACAGGGTTTTGCCATGTTGCCCAGGCTGGTCTCGAACTCCTGAGCTCAAGCAATCCTCCC ACCTCAGCCTCCCAAATTGCTGGGATTACAGTCACGAGCCACCGTGCCGGGCTAGGACCC TTTTTCTTGTTGTCGTTTTTGAGACAGAATCTCCCTCTGTCACCCAGGCTGGAGTGCCGT GGCGTGATCTTGGCCCACTGAAACCTCTGCCTCCTGGTTCAAGCAATTCTCGTGCCTCAG CCTCCTGAGTAGCTGGGATTACAGGCATCTGCTACCACACCTGGCTAAATTTTGTATTTT TAGCAGAAATGGGATTTCACCAGGGCCAGGCGCAGTGACTCATGCCGGTAATCCTAGCAC TTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCATCCTGGCTAACA TGGTGAAACCCCGTCTCTAGTAAAAATATAAAAAATGAGCCGGGCGTGGTGGCGGGCGCC TGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAG CTTGCAGCGAGCCCAGATCGCACTGCTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCG TCTCAAAAAAAAAAGAAATGGGGTTTCACCATGTTGACCAGGCTGGTCTCAAACTCCTGA CCTCAGGTGATCCGCCCACCTCAGCCTCCCAAGGTGCTGGGATTACAGACATGAGCCACC GTGCCCTGCCTGGCTAGGACCCTTTTCTGAGCCTATCTGGGCTCCCCAGAATCCTGTCCT TTTCTCACCCACCTGGGCCACGGGATCTCCAAGTGACCATGCCTACAATCCCAGGACCTC CCTTCCCGCCTACAGCTGAGCCCCTTCCTCCCCAGGTCCCAGTTCATCCGCCTGGTCTTC ATCACCACTGTGGTCAGCACCCTTCTGTCCTTCCTGCGGCCCACGGTCAACGCCTACGCC CTCAACAGCATTGCCCTGCACATTCTCTACATCGTGTGCCAGGAGTACAGGAAGTGAGTG AAGGCTGCAGGTGCCTGGGCAGGAGGCTCCCATCCCCCTCCTAGCACCCCTGACTCCAGG CTCGCGGAGGGGACGTCCCTTCTCCAAGATCACCCACTAACAAGTAGCAGGGCCAGGATT TGAACCTGACTGACTGCAGAGTTTGTCCTTATTATTATTTTTTTTCTTGAGACGGATCCT CGCTCTGTTGCCCAGGCTGGAGTGCAGGGGCGTGATCTTGGCTCACTGCAACCTCCACCT CCCAGGCTCAAGCAATCCTCCCACTCCAGCCTCCCAAGTAGCTGGGACTAGAGGCGTATG CCATCATGCCAGGATAATTTTTGTATTTTTCTTTGTAGAAACAGGGTTTCGTCATGTTGC CCAATCTGGTCTTGAACTCCTGGGCTCAAGCGATCCACCCACCTCAGCCTCCCAAAGTGC TGGGATTACAGGTGTGAGCCACTGCATCCACCCTACATTATCTTTATTTTATTTATTTAT TTATTTATTTTTGAGACAGAGTCTCTCTCTGTCTTCCAGGCTGGAGTGCAGTGGTGTAAT CTCAGCTCACTGCAAACTCTGCCTCCCGGGTTCAAGGATTCTCCTGCCTCAGCCTCCCGA GCAGCTGGGAGTACAGGTGTATGCCACCATGCTCGGCTAATTTTTGTATTTTTAGTAGAG ACGGAGTTTCGTCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCTGCCC ACCTCGGCCTCCCAAAGTGTTGAGATTACAGGCGTGAGCCACTGTGCCCAGCAGAGTTTG TCCTTTTTATGATGAAACCCAGAAACAGACATGCAAGCAGAGAAAATAGCCCCACAAACC TCCCCACGCCCACTAACCAGCCACAACAACCACCCACATTTTGTCAATCTGTTACATATT TCTCCCAGATTTCATACAATTTCACCCCTAATTTTTTTTTATAATTTAACTCCCCTGATT ACAAAAAATATATTATTCTTGCTGGGCATGATGGCTCATGCCTGTAATCCCAGCACTTTG AGAGCTTGAGGCACACATACCTCTACCCCAAAACATACAAGCACCAAAGGGCTTGTTGGT TAAGAATAAATACTATGCAGTCAGAAAAACTTGGTTTAGATCCCAGCTCTGCCACTTACC AGCTGTGTAACCATGGGGTGGGGTGGGGCATAGTGCAATCCCTGTGCCTCAATTTACTCC TCTACAAAGTCCTTGTGAGGACTGAGTTAATATCTTTTTTTTTTTTTTTTTTTTGAGACG GAGTCTCACTCTTGTCGCCCAGGCTGGAGTGCAATGGTGCGATCCCGGCTCACTGCAATC TCCACCTCCTGGGTTCAAGCGACTCTTGTGCCTTAGCCTCCTGAGTAGCTGAAATTACAG ACACACGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGAGTTTCGCCATG TTGGCCAGGCTGGTCTCGAACTCCTAACCTCAGATGATCTGCCCGCCTCGGCCTCCCAAA GTGCTGGGATTACAGGCTTGAGCCGCCGCGCCCAGCTGACTGAGTTAATATTCGAAGGTG TTTAATTTATTATTGTTACTTGTTTTTATTTATTTATTTATTTATTTAAGATGGAGTCTC ACTCTGTCACCCAGGCTGGCGTGCAGTGGCGCAATCCCGGCTCATTGCAACCTCCGCCTC TTGGGTTCAAGTGGCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGGCCACCACCATGGC CGGCTAATTTTTTTTTTGTATTTTTAGTAGAGTCAGAGTTTCACCATGTTGGCCAAGCTG GTCTCAAACTTCTGGCCTGAAGTGATTCACCTGCCTCAGCCTCCCAGACTTCTGGGATTA CAGGTGTGAGCCATCACGCCCGGCCTATTATTGTTTTTTAAGACAGGGTCTTACTCTGTC ACCCAGGCCGGAGTGCAGCGGCGCAATCACGGCTCACTGCAGCCTTGCACTCCTGGGCTC AAATGATCCTCTTGCCTCAGCCTCCCGAGTAACCGGAACTGCAGGCATGCACCATCATGC CTGGCTAATTTTAACTTTTTTTTTTTTTTTTAGAGATGGGGTCTTGCTATTTTGCCCAGG CTGGTCTTAAACTCCAGGGCTCAAGCGATCCTCCCAACCTCAGCCTCCCAAAGTGCTGGG ATTACAGGCATGAGCTACTATGCCTGGCTTGAAGGACATTTGGAACTGCACCTGTTGTGC TGGAAATGCTGTGTTAGTTCTAAGCACGAGATTGGGCCCCCTCTGCTTGCACCCTCAATT CCTGCTCTTTCCCTTCTCCCAACCTCTGAGCCTCATCACTGTGGAAGGAGGAATTTCCCA TCAGCCCCATCAGGTGCTGCTCTCCGAGCCAGCCCCTGGTCCCCCTCTCCCCTCTCTAGG ACCAGCAATAAGGAGCTTCGGCACCTGATTGAGGTCTCCGTGGTTTTATGGGCTGTTGCT CTGACCAGCTGGATCAGTGACCGTCTGCTTTGCAGCTTCTGGCAGAGGATTCATTTCTTC TATCTGCACAGCATCTGGTAAGCACATGCTCTGAGGCTGTGGGGGGCCCAGAGTCAGAGA ATCTTAGATGCCAAAGCTCGGAGTAGGCACCTGGGGGCTGGGGTTGGAGAAGCAGAGAGA GGAGAGCCAGACACTGGGACCTGGCGGTAGGGGAAGGCTGCAGTCACGGGGCCAGACCCA GAAGGCTCCCCTGGATGGATGGTCAAGAGCCATGAGAAGTAAAAAGAGGGCCGGCGTGAG GCTGTGGGTATCTTGTGCCCTCGCCACCTTCGCCCTGCACTCCACAGGCATGTGCTCATC AGCATCACCTTCCCTTATGGCATGGTCACCATGGCCTTGGTGGATGCCAACTATGAGATG CCAGGTGAAACCCTCAAAGTCCGCTACTGGCCTCGGGACAGTTGGCCCGTGGGGCTGCCC TACGTGGAAATCCGGGGTGATGACAAGGACTGCTGAGACCTGCCAGCCTCTTGACTATCC AACCACCCAACAACTTGCCTGTGTCTTGAGAAGATAGCCCCGGTCAGGACTTGCACCTGC GGGACACTCGTGGTTCCTTCCTCTGTTTCCCCTTCCGTGTCCTCCTTGTCCTGCGCTGCC CTGCCTTGAGGCAGATGATGGACTTTGTGACATCTCTGAGCAGCAGCCTGGTGACTGTGG GGGGCTGTCTC OMIM ID 613491