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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADH5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID128
Official gene symbolADH5
Full namealcohol dehydrogenase 5 (class III), chi polypeptide
Aliases,ADH-3,ADHX,FDH,GSNOR,
Gene summaryThis gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q21-q25
Gene position100009931 - 99992129  Map Viewer
Gene orientationminus
Gene size17803 bp
Gene sequence
OMIM ID103710