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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACMSD (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID130013
Official gene symbolACMSD
Full nameaminocarboxymuconate semialdehyde decarboxylase
Aliases,-,
Gene summaryThe neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM]
LocationChromosome: 2   Locus: 2q21.3
Gene position135596186 - 135659604  Map Viewer
Gene orientationplus
Gene size63419 bp
Gene sequence