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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for COMP (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1311 Official gene symbol COMP Full name cartilage oligomeric matrix protein Aliases ,EDM1,EPD1,MED,MGC131819,MGC149768,PSACH,THBS5, Gene summary The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq] Location Chromosome: 19   Locus: 19p13.1 Gene position 18902114 - 18893583  Map Viewer Gene orientation minus Gene size 8532 bp Gene sequence >COMP:complement(10156385..10164916):Length=8532 AGAAAGCGAGCAGCCACCCAGCTCCCCGCCACCGCCATGGTCCCCGACACCGCCTGCGTT CTTCTGCTCACCCTGGCTGCCCTCGGCGCGTCCGGACAGGGCCAGAGCCCGTTGGGTAAG CCGCGTTAGCACCCGCGCCGTGCCCACGGCCCCACAACGGACTGTAGGACCCGTGAGAGG CCCGGGATCCAGGCTGTTTGGGGCTCACGGACTGTTCGTAGGGGACGTGCCGGGCGCAGA AAGCAGGTGGCGGGACCGAGACTAGAGGAGCGCAGTGGGGCCTCGGAGGTCCGGGTTCGC TGCAACGGTGGGAGTTGGTGGTGGGATTCCCCGGCCCCATGACGCCTCACCAGGTCCCCT GCCGCCGCAGGCTCAGACCTGGGCCCGCAGATGCTTCGGGAACTGCAGGAAACCAACGCG GCGCTGCAGGACGTGCGGGAGCTGCTGCGGCAGCAGGTGCGGGGCCCGGGTGCGGGGCAG GGAGTGCCAGGGAACGGAAGGGGGTCTCAGTTCCCAGCGAGGAGAGAGGAAGTACCCGAG AAGGTGGAGAGGAGATGGGGAGGGAAGGGGGTCGGCGGGTAGGGAGTCCTTGGCGAAAAG AGGCTGTAGAAAGGGACCCCGGGGTAGAGAGAGGGGAGACCCGAGGGATGAGGAGAGGTT GGGACCCCGCTGATTCCATCCCACCCCTGCAGGTCAGGGAGATCACGTTCCTGAAAAACA CGGTGATGGAGTGTGACGCGTGCGGTGAGCGCGGCGGGGCGGTCGGGAGAGAGAAGAGAC GGGAGACAGAGACACAGAGACAGAGACAGAGAGCCAGGGAAAGCTGGGGAGGAAAAGAGA CGGAAGGAGATGGAGGCTGACGGAGAGGTGGACGGACGAACGGGAATGGGATGGGGTGTG TAGAAACAGAGACAAAAAGAGACAGAAGCGGTGAGAGAGTTTTGGGGAAGTGAGAGACGC CACGGGGCAGAAAAGCGGGACAGAGACTCAGAGAAGAGACCGGGGAGACCCCGCGGTCAG AGCGCGCAGCCTCTGGGGCGGGATCGCGGACAGCGCAGGATTTCGGGCCGCCCCGGGGCG GGGGGTGGGGGGGAAGGGGAAGCCTCCAGCCCCGGGGCGTGGCCATGATAGGCTCTGCCC CCGGGCGAGCCACCGATCAGCCCCGCCGCTTCTCCCCCCTCCCCCCCGCAGGGATGCAGC AGTCAGTACGCACCGGCCTACCCAGCGTGCGGCCCCTGCTCCACTGCGCGCCCGGCTTCT GCTTCCCCGGCGTGGCCTGCATCCAGACGGAGAGCGGCGCGCGCTGCGGCCCCTGCCCCG CGGGCTTCACGGGCAACGGCTCGCACTGCACCGACGTCAACGAGGTGCGCTAGCCCCGAC ACTCCACCGCCCTGACGACTCCCTCTACCGCCCCCCAATCTCTCGCCGCCCGGGAGACCC CTTCCTCCACTGGGAGTGTTCGCCCCGAAGAGCCTCTCACCTCCGGGGGCGCACGGCCAG ACTACCTCCTTACCGCGGGGGGACGCCCAACCCAAGGACCATCCCCGTCACCACCCGGGA CGCCCGCCCCCACAACCCCCTACATAGCTAGTGACGCCCGCCCCGACGACTCCCTCACCG CCAGGGGTGGTCCGCCCCAGCTACCCTCCTCGCCGCAGGGGATCGCCAGTCCCAACGACC CTTCCACAGCCAGGGAACGCACGCCCAGACCCCCCGCCACCGCCGGGCACGCACGCCCCG ACGACCCCTGCCCCCCTCTGCTGGGGATGCCCGCCCTCATCCTTCCTCCCCTCGCCCATG AGGGAACAGCTCTCCTCTCCTCTCCCGGTTGCGCCCTTGCCGTCATCAAGGCAAAGTCGT GCCTGACCCCTGCGACAATTGCTTCCATCTCAGAGCTCCAAGCACTGGCATATGGCCCTT GAACTTTCCACATCCGAGACACTACGAGGTGCGGCCCCCAGGGCCCAGCTCGAAGCCCTC TGACCCTCTGTGGCCCCTCCTCCCCCAGTGCAACGCCCACCCCTGCTTCCCCCGAGTCCG CTGTATCAACACCAGCCCGGGGTTCCGCTGCGAGGCTTGCCCGCCGGGGTACAGCGGCCC CACCCACCAGGGCGTGGGGCTGGCTTTCGCCAAGGCCAACAAGCAGGTGAGAGGTGTGGG GGCCCCATTTTTGGAGCAGAAGGGAAGGGGGCGTCCATTTTGTTTACCAGTAAACTCCTC TTCCAGCCTCCTTCCAGCGGGAGGGGTGGGGAGAGGAGGGGTCCGCTGCGCCAGGGCTGA TCGGTTTGGGGCAGGATGGAGGGGAGAGGCAGGATGCGGAGGAAGTGTGGAGGAGGTGGG AGGTCCGGAGGTGTCTGCGTGGGGTGGTGACCTCTGAGTTCCCCTCCCCTAGGTTTGCAC GGACATCAACGAGTGTGAGACCGGGCAACATAACTGCGTCCCCAACTCCGTGTGCATCAA CACCCGGGTAAGGCCCGCTGGGGAGGAAGAAAGGATCGCGGGAGGTGGGGCGAGCGGCGG GCGGCCTGCGCTGACCTCCGGCGGCTCCGGCGCAGGGCTCCTTCCAGTGCGGCCCGTGCC AGCCCGGCTTCGTGGGCGACCAGGCGTCCGGCTGCCAGCGGCGCGCACAGCGCTTCTGCC CCGACGGCTCGCCCAGCGAGTGCCACGAGCATGCAGACTGCGTCCTAGAGCGCGATGGCT CGCGGTCGTGCGTGGTGAGTGCGGGCGGGCTGGGCTTGAGGCGGGGTTGGGTGGCGGCCA CTCCAGGGCACCCACTTACACTCTCCCACAGTGTGCCGTTGGCTGGGCCGGCAACGGGAT CCTCTGTGGTCGCGACACTGACCTAGACGGCTTCCCGGACGAGAAGCTGCGCTGCCCGGA GCGCCAGTGCCGTAAGGTGGGTGGGGGCGGAGCGGGGCGGGCTTGGGCAGGAGGGAGGGC GGGACTTCATGACCGCGCCCCTCACACCTTCTGTGCCCGCCCCCAGGACAACTGCGTGAC TGTGCCCAACTCAGGGCAGGAGGATGTGGACCGCGATGGCATCGGAGACGCCTGCGATCC GGATGCCGACGGGGACGGGGTCCCCAATGAAAAGGTAGATCTACGGCTCGGCACGGTGGT TCACTCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAAGAGA TGGAGACCATCCTGGCCATCATGGTGAAACCCCTCCTCTACTAAAAATACAAAAATTAGC GGGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCG CTTGAACCCGGGAGGCGGAGGTTGCAGTCAGCCGAGATCGCGCCACTGCACTCCAGCCTA GCGACAGAGCAAGACTCTGTCTCAAAAAAAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAG AAAGAAAGAAAGAAAGAAAGAGAAAAAGAAAAAGAAAAAAGAAAAGACAGAGCTGTGAGC GGGGCCTAGGGAAGTGGGATGGGGCGTGGCTTGGATGAGGGGCGTGGCCTCCGTGGTCTA GGAGGGGCGAAAGGTTCCTTGAGGAGGAGACGCGTCCTCGGAGATTTGGGAATCTGAGGA GTGTGACCTTTGCCTTCTCGACCTGATCTCACCCTTAACCCACCCTGTCATCCAGGACAA CTGCCCGCTGGTGCGGAACCCAGACCAGCGCAACACGGACGAGGACAAGTGGGGCGATGC GTGCGACAACTGCCGGTCCCAGAAGAACGACGACCAAAAGGACACAGACCAGGACGGCCG GGGCGATGCGTGCGACGACGACATCGACGGCGACCGTGAGCTCGATGGGGGTTGGGGGGC GAGGAGAGGCGGCGGGCACCGAAGGGCGGGATTCGGCTCCGGGGCGGGGCTTGGCTGGTT TTGGAAGCCGGATGGGGTAAGCTGGACTAGGGCGCCCTGGACCAAAGACCATGGTGGGGC GCCAGAAAAATGCAAGCTGGGCTGCAAGGCCAGGAAAAACGCAGGGATATTTGGAAGGGA AGGTGGTCCCTGTGTCAATGCCGCAGGCAGGAATTAAGAGGACAAGAGATTCGAGCCTGG GGTTTAGGACCTGGGAGGTGACAACTTTACAGATGGGGACATAGGGGCTCAGGGTGGCAC ACACGGGCACCCAGCTGAGCCACCCTGGGAGTGAGAGCCCGTCCCCCTCACTAGCCTTCC CTTGGATGGGACCATTCATTCTTAAAGTTCCTGTGGGCCGGACGGGGTGGCTCATGCCTA TAATTCCAGAACTTTGGGAAGCTGAGGCAGGTGGATCACGAGGTCAGGAGTTCGAGACCA GACTGACCAACATGGTGAAACTCCGTCTGTACTAAAAATACAAAAATTTGCTGGGCGTGG TGGCGCACACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCATTTGAACCC GGGAGGTGGAAGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGAGTGACACA ATGAGACTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGCTTCCATGAAGTTGGGA CTCTGTTCCAGGCCAGCCTCAGGCTGGCTCATCCTAATGAAGTCATTCTGGCCTGGTCCC AATCTTGGGGCTCTGGTCCCGTGGATTTCTGCAGGGATCCGCAACCAGGCCGACAACTGC CCTAGGGTACCCAACTCAGACCAGAAGGACAGTGATGGCGATGGTATAGGGGATGCCTGT GACAACTGTCCCCAGAAGAGCAACCCGGATCAGGTGAGGGCAGGCCAGACTCCAGCTGGG TAAGCCCTCTGGGTGAACTGCAAGTTGGATTACCCAGCCCACAGCCCAGCTTAGAGCATT TTACACTGCCAGAGAAATGACCTCTCGGTCCGAGCAGCCTGCGGTGGGGGTTTCCTTGGG GTCAGGAGGACCTTGGCTGTGCGGCTGGGTTGGGTGGGAGGCTTTCTGATTTCCTCTGTC TGATTATGGACCCCCGCATGCTGCCCTCCGCAGGCGGATGTGGACCACGACTTTGTGGGA GATGCTTGTGACAGCGATCAAGACCAGTAAGGAGGCCACCTGGGGTGGGCGTCCGGGTAG CCTTTGACAAAACGCTCTGGAGAGCTCATTGTCTCTGGATCCCACCTATCCACTCTAGGG ATGGAGACGGACATCAGGACTCTCGGGACAACTGTCCCACGGTGCCTAACAGTGCCCAGG AGGACTCAGACCACGATGGCCAGGGTGATGCCTGCGACGACGACGACGACAATGACGGAG TCCCTGACAGTCGGGACAACTGCCGCCTGGTGCCTAACCCCGGCCAGGAGGACGCGGACA GTACGGCGGGGGCGGGGCCTGCGGTGGGGGCGGGGCCAGTGGGGGCTCCTGGCGCGGGGT CTACGGTGGGCGGGCCCTGACTTTAGCCCACCGAGGGGTCTCCCACCTCTCAGGGGACGG CGTGGGCGACGTGTGCCAGGACGACTTTGATGCAGACAAGGTGGTAGACAAGATCGACGT GTGTCCGGAGAACGCTGAAGTCACGCTCACCGACTTCAGGGCCTTCCAGACAGTCGTGCT GGACCCGGAGGGTGACGCGCAGATTGACCCCAACTGGGTGGTGCTCAACCAGGTGGGAGC GGGGTCCACGTGGGGGGTGATGGGACCCTAGAACCCCCACAGTGAGGCCTATGCTGAGGA CAGGGTGCCTAGGGCTGTCACGGCCAGCCTGAGGCCCTCCTTTCTTTGACCCCATCAGGG AAGGGAGATCGTGCAGACAATGAACAGCGACCCAGGCCTGGCTGTGGGTGAGAAGCGGGG AGCAGCGCTATCCTGCCACGGAGCGGGCTCAGGGAGAGGGGCCAGAGAAGGGGCAGGCCC GGGCTGAGAATGGGCGGGGCCAGAAGGGGGCTGGCCCGGGCTCAGGAAGGGCGGGGACAG AGGGGCGGGGTTATATGGGCGGGCCCGGGAGGAGAAGGCGCGGGGCCAGAGGAGGGGCGG GCTCGGGAAGGGCGGGGCCAAGTGGAGGTGGACTCTGGAGGGGCGTGGCCAATGGTAGAT GGGGGGCGTGGCTGAGTCCGGGCTCTGCGAGTGGGAATGGTGCAGGTCTGCAGGCAGATC GGGACCCAGGGGGCAGGTTTGGGTTCTGGGTGCCAGGTTCCGGGGGCTGGGGCTGGCGTT CGGAAAGGCCACTGCTCTCTTTCCATCCCTAGGTTACACTGCCTTCAATGGCGTGGACTT CGAGGGCACGTTCCATGTGAACACGGTCACGGATGACGACTATGCGGGCTTCATCTTTGG CTACCAGGACAGCTCCAGCTTCTACGTGGTCATGTGGAAGCAGATGGAGCAAACGTATTG GCAGGCGAACCCCTTCCGTGCTGTGGCCGAGCCTGGCATCCAACTCAAGGTGCCAGGGCC GTCCGTGCCTGACCTCTGCGGTCCTCATGCCCTCCCATGACCCTCCGTAAAACCCTTTAC AGCCCTTAGAGCCCCCCAGCCCCCTAGCCTCATACTATGGACCTCAAAGCTGTCCCAGCC CTCCTCTGGGCTCCCGCAGTCCCCAAATCCTCCCAGTTCCTTGCACAAATTCTCAAACAT TCTCAGGGCCCCCCAGTCTTCCTATGGACCCTAAACCCTCTCACACAGCCCTAAACTTTT CCTTAGTTTCCAAGTCCTTCTGCAGAGCCCCCCATCCTCCCAGACCCTGAATCTGTCCAC GGACTCCCAAATCCTCTCATGAACCTGCAGACCACTGCTGCCCCCTGTGACCTATCCCCA AGCTGCCATTTGGCCCCTGAAGAAGGCTTCCTTGTGGGTCTCTCATCCGGATCCCCCTGG CCGCCCACCACCTGCTGCTCCCAACTGTCTCTCCAGGAAGGTGTCTAGGGGGGCTCCGGT GGCCCACGAGGTCTCTGACCACCTTTCCTGGGTATTGGCAGGCTGTGAAGTCTTCCACAG GCCCCGGGGAACAGCTGCGGAACGCTCTGTGGCATACAGGAGACACAGAGTCCCAGGTGC GGCTGCTGTGGAAGGACCCGCGAAACGTGGGTTGGAAGGACAAGAAGTCCTATCGTTGGT TCCTGCAGCACCGGCCCCAAGTGGGCTACATCAGGTGGGGACTCCACCCTCTGTGGTGGG CTGGGCTGGGGACACACAGGCCCAGGTGGGAGTGCCCTGGCCAGGCAGGGGCTGTGTGAC CCTGGTCCCCTCATCTGTACGATAGGAAAGATACAGGGCAGTTAGAATGAGCCTATGCTG GTCCAGGCGTGGTGGCTCACACCTGTAACCCCATCACTTTGGAAAGCCAAGATGGGAGGA TCGCTTGAGCCCAGGAGTTCGAGGCAGCCTGGGTAACATAGTAAGACCCTGTCTCTACAA AAAAGAAAAAAATTAGGCCAGGCGCAGTGGCTCATGCCTGTAATCCCAGTACTTTGGGAG GCCGAGGCGGGTGGATCACCTGAGGTCCGGAGTTTGAGACCAGCCTGGCCAACATGTTGA AACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGGCGGGGCCCTGTCATC CCGGCTACTCAGGAGGCTGAGGCAGAAGAATCGCTTGAACTCGGGAAGCGGAAGTTGCAG TGAGTGGAGATCGTGCCATTGCACTCCAGCATGGGTGACAAGAGTGAGACTCTGTCTCAA AAAAAAAAAAAAATGCCAGGCATGGTGGCACGTGCCCATGGTCCCAGCTACTAGGGAGGC TGAGGTCAGTTGAGTCTGGGAATTAAGGTGGCAGTAATTGCACCACTGCACTCCAGCCTG GGTGACAGAGCGAGACCCTGGCCAGGACACAGCACACAGTGTGTATCCAGCTAGAAATGG GGCCTCACCCAGTCCCTGTTTCTCAGCCTCCATTCCATGCTGCTAGCAAGCCCAGGTGCT CTGTTTAGCACCAACTATGTCCAGGGCCCTTGATGTCCACCACACCAGGAAACTGAGGCC CAAGGCAGAGGCCTCACTTGCTCCCAGTGCAGCCCAGTCAGGGGTACCCATCTTCCAGGG CTGGCCACTGAAGCTCTGAGAGGGAAGGGTCTGGCCCAGGTCCCCCAGGCCTCACCATGT CTGACCCTCAGGGTGCGATTCTATGAGGGCCCTGAGCTGGTGGCCGACAGCAACGTGGTC TTGGACACAACCATGCGGGGTGGCCGCCTGGGGGTCTTCTGCTTCTCCCAGGAGAACATC ATCTGGGCCAACCTGCGTTACCGCTGCAATGGTGAGCCGAGGGCCAGCGGGCCGTGGGCG GGGAGTCTGCACACAGGCCCTGCTGGCCTTCTCAGCCCTCACCCGCCTGCCCTCTCCCTG CAGACACCATCCCAGAGGACTATGAGACCCATCAGCTGCGGCAAGCCTAGGGACCAGGGT GAGGACCCGCCGGATGACAGCCACCCTCACCGCGGCTGGATGGGGGCTCTGCACCCAGCC CCAAGGGGTGGCCGTCCTGAGGGGGAAGTGAGAAGGGCTCAGAGAGGACAAAATAAAGTG TGTGTGCAGGGA OMIM ID 600310