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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADK (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID132
Official gene symbolADK
Full nameadenosine kinase
Aliases,AK,
Gene summaryThis gene encodes adenosine kinase, an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q22|10q11-q24
Gene position75910965 - 76469060  Map Viewer
Gene orientationplus
Gene size558096 bp
Gene sequence
OMIM ID102750