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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CORT (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1325 Official gene symbol CORT Full name cortistatin Aliases ,CST-14,CST-17,CST-29, Gene summary This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. [provided by RefSeq] Location Chromosome: 1   Locus: 1p36|1p36.22 Gene position 10509971 - 10511959  Map Viewer Gene orientation plus Gene size 1989 bp Gene sequence >CORT:6514703..6516691:Length=1989 GCGTTCCAAAATAAGAGCAAATTCGCTCTAAACACAGGAAAAGACCTGAAGCTTTAATTA AGGGGTTACATCCAACCCCAGAGCGCTTTTGTGGGCACTGATTGCTCCAGCTTCTGCGTC ACTGCGCGAGGGAAGAGGGAAGAGGATCCAGGCGTTAGACATGTATAGACACAAAAACAG CTGGAGATTGGGCTTAAAATACCCACCAAGCTCCAAAGAAGAGACCCAAGTCCCCAAAAC ATTGATTTCAGGGCTGCCAGGAAGGAAGAGCAGCAGCAGGGTGGGAGAGAAGCTCCAGTC AGCCCACAAGATGCCATTGTCCCCCGGCCTCCTGCTGCTGCTGCTCTCCGGGGCCACGGC CACCGCTGCCCTGCCCCTGGAGGGTGGCCCCACCGGCCGAGACAGCGAGGTGAGTACAGT CCCGACGTGGCCACACGCTAGCCCACTCTCTGTCTCTTGTTGGCTTTTTGGCCTGCATGG TGTGTGTGTGTGCACGTGTGTTGCACTTCACAGCTTGGACAGGACACACGGCTCAACTTT GTAGTGTTCTTGGCTGGCCCGAGGTACTGGGATGCCGCATTCAGACCACTGATCCTCAGT TACATGTCCCAACCCATGAAGCCTGCTGGAAACCTGTGCAGCTCAAGGAGGGCCCTCCGT CGGGTGTCTGGGAAAGGGGAAGCGAGTGTACCCGTCCACTGCAGGGCAGGCATGGAGCTG CGACAGCCCTTCCAGAGCCTTCAGTTATACATAGCACAGGCTCCCACTGGCTCAGAGTAA TTGGCATCATTACATTTTCCGTTGTGAGAATTTGTAACTTCGTGAGGTGATTGATTGTTC TTTTTTCCATTTTGAGAAAGTTCCAAGAAAGGGTATATAAAGTTGAGCATTAAAAATGGA TTTTTCTCTAAAATTACCAGATGAGTTTCAGGCAGGCCATTTATCAGCAGATTACTCCCA GAAGCTTTCTAAGGAATTTGAAAAACCAGAATATAACGTTTGTTTCAGTCCCATCGTCTC AGAAAGCAACTTGTGAACATCCAGGAGTGTGGCCAAAGGTGGGAGAATGAGTAAATTAGC CTGATCCAACTCCGGGCTTCTCAGCTGCCAGTCACTGAGGGGAAAATGGCAGATTTCCCG ACCTCTCCTAATTAAGGACCTTAGCAGAGTATGGAGCAAAACCAGGTTTCTTCCCTTGAC TTAAAATGACCAACTTTTCTCTAATTAAAGCAATTTCTTTAAGGTATTCTCTTCACTTTC TCATCCTCATCCGTTAAATGGAAATGAGGCTTATCGCTATGGAGCATCTTTTCATTTTAA TATTTTCTTTCTCTTTTCTCCAGGGTAGTCTTTTAGATCATTTTTTTTTTTAAGTAAGGA GGAGATTGCATATCTTTGAATGCTTGCTGCCTGAGCCAGATTGCTGAGTTTTCTTTCCTT TGCCATCTGCTTCTCTTTAAAAGCATATGCAGGAAGCGGCAGGAATAAGGAAAAGCAGCC TCCTGACTTTCCTCGCTTGGTGGTTTGAGTGGACCTCCCAGGCCAGTGCCGGGCCCCTCA TAGGAGAGGAAGCCCGGGAGGTGGCCAGGCGGCAGGAAGGCGCACCCCCCCAGCAATCTG CGCGCCGGGACAGAATGCCCTGCAGGAACTTCTTCTGGAAGACCTTCTCCTCCTGCAAAT AAAACCTCACCCATGAATGCTCACGCAAGTGTAATGACAGACCTGAATAAAATGTATTAA GCAGCAGTGATCTTTCCTCTCCTCCTTCCCAAGTCATTTGAAAAGTGTTTGTTATTTAAA TTCCAATAATGCCCAATACTGACGTGTCTTGAGTAATTTGGAACCCAAAGTGAAGATCTT TGATAAAGATTTTTTTGTGGTTCGACTGGACTGTGCTGAGTGCGGGCACTGGGCTTTTCT TCTGATGTTCATTATGGTGCTGGGAAGCTCTGTCTTTGATTTAAAATAAAATAGCTAAAG GCTACACAA OMIM ID 602784