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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PPARGC1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID133522
Official gene symbolPPARGC1B
Full nameperoxisome proliferator-activated receptor gamma, coactivator 1 beta
Aliases,DKFZp686C1790,ERRL1,FLJ14284,PERC,PGC-1(beta),PGC1B,
Gene summaryThe protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q32
Gene position149109815 - 149234585  Map Viewer
Gene orientationplus
Gene size124771 bp
Gene sequence
OMIM ID608886