Entrez gene ID | | 1351 |
Official gene symbol | | COX8A |
Full name | | cytochrome c oxidase subunit VIIIA (ubiquitous) |
Aliases | | ,COX,COX8,COX8-2,COX8L,VIII,VIII-L, |
Gene summary | | The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q12-q13 |
Gene position | | 63742079 - 63744015 Map Viewer |
Gene orientation | | plus |
Gene size | | 1937 bp |
Gene sequence |
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OMIM ID | | 123870 |
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