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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PACRG (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID135138
Official gene symbolPACRG
Full namePARK2 co-regulated
Aliases,FLJ32724,GLUP,HAK005771,PARK2CRG,RP3-495O10.2,
Gene summaryThis gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 6   Locus: 6q26
Gene position163148164 - 163736524  Map Viewer
Gene orientationplus
Gene size588361 bp
Gene sequence
OMIM ID608427