| Entrez gene ID | | 1365 |
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| Official gene symbol | | CLDN3 |
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| Full name | | claudin 3 |
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| Aliases | | ,C7orf1,CPE-R2,CPETR2,HRVP1,RVP1, |
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| Gene summary | | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq] |
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| Location | | Chromosome: 7 Locus: 7q11.23 |
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| Gene position | | 73184600 - 73183327 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 1274 bp |
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| Gene sequence |
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| OMIM ID | | 602910 |
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