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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CLDN23 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 137075 Official gene symbol CLDN23 Full name claudin 23 Aliases ,CLDNL,hCG1646163, Gene summary This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq] Location Chromosome: 8   Locus: 8p23.1 Gene position 8559666 - 8561617  Map Viewer Gene orientation plus Gene size 1952 bp Gene sequence >CLDN23:1035017..1036968:Length=1952 AGGAGGGCGGAGCGGCCGGGACGCCAGGAGGGAACTAGCCTAAGTGGGGACGGTCCCCGT GCAGGAGACAAAGAGCGTCCCTGGAGCGATCAGGGCTCAGGAGCCCGACCCGGAGCCCGG GGCGTCCGCGCTGACTTCGGGTCCCCGGAGCCTGGGGCACGGCAGGGAGAAGACGACGGC GGAGAAGGCGACAGCGGAGAAGGAAGGCAGGCTGCAGGGGCGCCGTCGGCGCGGCGGGCC GGGATGCGGACGCCGGTGGTGATGACGCTGGGCATGGTGTTGGCGCCCTGCGGGCTCCTG CTCAACCTGACCGGCACCCTGGCGCCCGGCTGGCGGCTGGTGAAGGGCTTCCTGAACCAG CCAGTGGACGTGGAGTTGTACCAGGGCCTGTGGGACATGTGTCGCGAGCAGAGCAGCCGC GAGCGCGAGTGCGGCCAGACGGACCAGTGGGGCTACTTCGAGGCCCAGCCCGTGCTGGTG GCGCGGGCACTCATGGTCACCTCGCTGGCCGCCACGGTCCTGGGGCTTCTGCTGGCGTCG CTGGGCGTGCGCTGCTGGCAGGACGAGCCCAACTTCGTGCTGGCAGGGCTCTCGGGCGTC GTGCTCTTCGTCGCTGGCCTCCTCGGCCTCATCCCGGTGTCCTGGTACAACCACTTCTTG GGGGACCGCGACGTGCTGCCCGCCCCGGCCAGCCCGGTCACGGTGCAGGTCAGCTACAGC CTGGTCCTGGGCTACCTGGGCAGCTGCCTCCTGCTGCTGGGCGGCTTCTCGCTGGCGCTC AGCTTCGCGCCCTGGTGCGACGAGCGTTGTCGCCGCCGCCGCAAGGGACCCTCCGCCGGG CCTCGCCGCAGCAGCGTCAGCACCATCCAAGTGGAGTGGCCCGAGCCCGACCTGGCGCCC GCCATCAAGTACTACAGCGACGGCCAGCACCGACCGCCGCCTGCCCAGCACCGCAAGCCC AAGCCCAAGCCCAAGGTCGGCTTCCCCATGCCGCGGCCGCGGCCCAAGGCCTACACCAAC TCGGTGGACGTCCTCGACGGGGAGGGGTGGGAGTCCCAGGACGCTCCCTCGTGCAGCACC CACCCCTGCGACAGCTCGCTGCCCTGCGACTCCGACCTCTAGACGCTTGTAGAGCCTGGG GGGCGCCGGGTGGCAAAGGACTCACCCCCGCACAGGCCCGCCTGGCTTCGAGTTGGAACC CGGACACTTGCCCCTCACTGGTGTGGATGGAAATCTGCCTTTCGTGGGACCAAACAGGAC TCCTTGGACGATTAGTTCAGGTTGGGTTTGGTTTTCTTCTTAAAGAGTTTAGTTTTCCTC TCCAGAGGGATCAGGGTCCTCTTAGGGAGTGACGGGCTTTTCATATATTTTTGCTGAAGA ATATATGGAAAGGGTGGCATTTGCGTCACGTGGACCAGGGACAGTGCTGAAATCAGCAGT GCTCAGAAACAATTTAACATGTTGAAACGACAATATTCTAAAATACTGATGAATCTTGCA TCAATATAATTATTGGGTTTTTTTTCTTTTTCCTGCTGTATAACTCCTTGCCATGCAAAC TCTCAAGAGGCCAATATATTCCTGGCCATGTTTGAATGAGCCTCTTAAAATAAACTTAGA GCCATGCAAATGCCAGCAGCTTAATGGATTTCATGGAATGAAATACCGTGATTAACTCAT AGCTACATATCATTGCATAAATGGGATTTATCTTTTTTCTCACTTATTTTTGCGGTGAAA GTCGAGGGCATGCAAGAGTTTCTCTTCCAGAAGCCAAGAGGAGAACAAAGGTCCTAATGC TGTACTATTCCACCCTTTGGACGCCTCATCCAGGACGCAGAGGACTCTAGGTTTAACATT TTGTACAAAATGGAACCTGTTAATCATATTAAAGCACATATGTATATATCTTTTATTTAT AAATAAAATTTTAAAACAATAGTTTCAGTATA OMIM ID 609203