Entrez gene ID | | 1371 |
Official gene symbol | | CPOX |
Full name | | coproporphyrinogen oxidase |
Aliases | | ,CPO,CPX,HCP, |
Gene summary | | The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP). |
Location | | Chromosome: 3 Locus: 3q12 |
Gene position | | 98312455 - 98298290 Map Viewer |
Gene orientation | | minus |
Gene size | | 14166 bp |
Gene sequence |
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OMIM ID | | 612732 |
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