Entrez gene ID | | 1374 |
Official gene symbol | | CPT1A |
Full name | | carnitine palmitoyltransferase 1A (liver) |
Aliases | | ,CPT1,CPT1-L,L-CPT1, |
Gene summary | | The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13.1-q13.2 |
Gene position | | 68609399 - 68522088 Map Viewer |
Gene orientation | | minus |
Gene size | | 87312 bp |
Gene sequence |
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OMIM ID | | 600528 |
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