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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ATF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1386
Official gene symbolATF2
Full nameactivating transcription factor 2
Aliases,CRE-BP1,CREB2,HB16,MGC111558,TREB7,
Gene summaryThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q32
Gene position176032897 - 175939006  Map Viewer
Gene orientationminus
Gene size93892 bp
Gene sequence
OMIM ID123811