Entrez gene ID | | 1386 |
Official gene symbol | | ATF2 |
Full name | | activating transcription factor 2 |
Aliases | | ,CRE-BP1,CREB2,HB16,MGC111558,TREB7, |
Gene summary | | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q32 |
Gene position | | 176032897 - 175939006 Map Viewer |
Gene orientation | | minus |
Gene size | | 93892 bp |
Gene sequence |
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OMIM ID | | 123811 |