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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CRKL (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1399
Official gene symbolCRKL
Full namev-crk sarcoma virus CT10 oncogene homolog (avian)-like
Aliases,-,
Gene summaryThis gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
LocationChromosome: 22   Locus: 22q11|22q11.21
Gene position21271714 - 21308037  Map Viewer
Gene orientationplus
Gene size36324 bp
Gene sequence