Entrez gene ID | | 140460 |
Official gene symbol | | ASB7 |
Full name | | ankyrin repeat and SOCS box-containing 7 |
Aliases | | ,FLJ22551,FLJ25192, |
Gene summary | | The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: - |
Gene position | | 101142755 - 101191906 Map Viewer |
Gene orientation | | plus |
Gene size | | 49152 bp |
Gene sequence |
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