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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADAMTS14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID140766
Official gene symbolADAMTS14
Full nameADAM metallopeptidase with thrombospondin type 1 motif, 14
Aliases,FLJ32820,
Gene summaryThis gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This gene is highly similar to two family members, ADAMTS2 and ADAMTS3, in its sequence and gene structure, and the encoded protein shares the aminoprocollagen peptidase activity with the protein products encoded by ADAMTS2 and ADAMTS3. Various transcript variants of this gene have been identified. They result from the use of two different promoters and transcription initiation sites as well as alternative splicing sites. The full length nature of some transcripts has not been defined. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q21
Gene position72432559 - 72522197  Map Viewer
Gene orientationplus
Gene size89639 bp
Gene sequence
OMIM ID607506