Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CRYBB1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1414 Official gene symbol CRYBB1 Full name crystallin, beta B1 Aliases ,CATCN3, Gene summary Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, undergoes extensive cleavage at its N-terminal extension during lens maturation. It is also a member of a gene cluster with beta-A4, beta-B2, and beta-B3. [provided by RefSeq] Location Chromosome: 22   Locus: 22q11.2|22q12.1 Gene position 27013991 - 26995362  Map Viewer Gene orientation minus Gene size 18630 bp Gene sequence >CRYBB1:complement(6385931..6404560):Length=18630 ATAGCACCTGCCCGCCTGCCTGTCCTCCAGCAGGAAGTAGCAAGTCCCCAGGTAAGAGGG AACCCACAGCCCAGCTGAGAGCTGAAGGGGAGGGGAAGAGAAAAGGGAGACAGAGAGAGG GAGGCAGAGATAGCAGTGCCATGAGAGTCAGAGAGCAGGGCCATGGAGATAAAGACGGAA GTGGAGAGAGGAAGAAAGGGAGGGAGAGGGAGAGGGGAGAGAGTGAGAAAAGACAGAAAT AGAGAGAGAAGTAAATATAATTAAAAAGGACAGATAGAGAGATAAGCAAAGATACAATGA GGGAGAGATAGTGGGGGAGAGAGGAACAGAGAGGGAGAGAAACAGACAGGCAGATAGGCA GAAAGAGGGAGAGAAGTAAGAAACAGATAGAGAGGCAAAGACAGGGAAGAGAGGAGGAAC AGAGGGAGAGGGTGAAGCAGGGAGAGAGAGAGAATGAGAATATCTCCAGGAAGGCATGAG TCCAGCTGCCAGCCCTGGGGGAGTGTTTAAAGCCACAGATGTGGTCCAGATGTCTGGCCT CACCCCTGGTGAACAGGGGGCACCCCAGAATATGCACAGCCTTCCTGGAGGAGGCTGGGG GAGGGATGTGCTTATCCCAACTAGCTCCGCCTTACAGAATGTGTTCGGGAATCAGCTTGA CCAGAGGGTCTTAATCTGTGCTAGCAGGGGGTCCTCAAATCCCTTAACATTGTCTCCAAA GTTAAAGAGAGCATTATTTTTGTCCGGGGACAAAGTTGAGGTATTCATCAAACATTCAAA GGAGTCCACGACCCCAAAGCAACAAGGAACCACTGGAATTGACCAAAGCCCTCTCCACCC AAAGCCTACCCAGCCCCAGTCCTCATTTTCAGAACCCTCCACATGCAGTAAATACATCCT CTTGGGTCCTCCCATAAGCCTCAGTCCCCGGCCTGTATTTGCACCCATACACCAACCCCT CAGAGGAAGCAGACGGGGAAAGGAGCTGGGAGCATGCATTCATTCATTCTCTGAACAAAT GTTAATTGGGCATCTCCTATGTGCCAGGTGCAGAGCAAGTGTTAGGGATGGACGGTGAAT AAATCAGATTAAGCAAATGGCAGAATACTTTAAAAGCCCAGTTGCTGGCTCCATTTCCTT GAGTTGAAATCAGAGCCCTACCACTTAGTAGCTGTTTGGGCCTGAGCTGGGCCCCTTCCT TCTCCAGCCCCCTGCTGCTCAGAGGGGATCATGATAGCAGCTACTCCATCGGGTGAGGTT CATGGTCAGATGGGTTAATTAATGTATGTCACAGTGCCTGGCACACCTTAAGTACTCCCA AATGGGACTTCTTGTTATTAGTCTAGGGAGGCAAATTGGAGTTGCACAAGCAAATCAGTG TGATAAGCAGTGTGGAAAATTGCAGGGGGCTAAGGAAGGACCTAGCGGGGTAATGGAGGG TGGAACAGCTAGTGGAGGGAACCGCATGGTCAAAAGCCTGGAGGAAGGATATATGTGGGA TGAGTGGCCCCCAGACGGGAAGGTCTTGGCTGGGAAGTAGGGATGAAAGAAAAACTTCCA GGCTTAACCGTTTCAGAAGGAGATAGAGAGGAAACGAGCTCCAAGGAGGCTGAAAGCACA GGATGTGGGGCTATGAGGGCAGGAGGCAGTTTGGGGGTGTCATCCCTGAAGGCCAGAGTT TCTTTACAGACTTTTGCAGGCGGGAACCATGTCTCAGGCTGCAAAGGCCTCGGCCTCGGC CACAGTGGCGGTGAACCCAGGGCCTGACACCAAGGGGAAGGGGGCCCCACCTGCAGGAAC ATCCCCTAGTCCCGGCACTACCCTGGCCCCAACAACCGTGCCTATTACCAGCGCCAAGGC GGCGGAACTGCCTCCTGGGAACTACAGGGTAAGGACCTGGGGGTGCAGTGGCTGGGTGCC ATGCCTTCTTTCCTTCCTTCCCTCCTCCTCCTTCTTCTCCTCCTCCTCTTCCTCTTTCAC CTCTTACTCCTCCGCACCTCTTTCTCCTCCTTTTTCTTGGCTTATTTTCTCTCCTTTCTA TTTACTCTCCCTTTTCTTCTTCTCCACCTCCCCAGACTCTTATCCTCTGTCCCTATTCTC TTTTTCCCTCACCTTGGCCTCCTCCTCCCTCCTCCTTCTGGGACACAAGTGTGGCCCAGC CAATCTGGGAGCCCATAAAATAGCCAGGGGTTCTGACACACTTGGAGAAAGTGGGGCCGG GCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCT GAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAAT ACAAAAATTAGCCAGGCGTAGTGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAG GCAGGAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCTGAGATCATGCCACTG CACTCCAGCCTGGGCAACAGAGGGAGACTCCATCAAAAAAAAAAAGAAAAGAATAGAAAG AAAAAGGGGACCTATAGTTGAGTTGTGCAATAACAACAACCAAACCATACCGCTTCACAG CTGAAGGGACACCTGGCAATCAGGCTACACCTGCACACGCACATGCTTAGAGTTTATCGA AAGCAAGAAAAAAAAAGAAGAAAAGGAAGTGGGCTGGCTTAGCAGCAGGGAACCAGCTGT CCTTGGAGGCTCACTGGGGCAGCAGGATGGCCTCAGACCCTCAAAATTGCTCGAGGTGGT CTGGGCTGAAAGGCATCCTGTGGAGCAAGGTGTCCAGTCCCCTGGGATTTGGTTTGGTGT GGTTTCAACCTCAGGTCACAGAAGTAGGCCATTTTGCAACCCCTAGTTCATGACACGCTC TCATGTGGTCAGTGCGTGGCAGGTTTTTATTTATGTACCTATTTAATCATTAGTTTTATT TAATTTCTAATAATGCAATATGCACCTACAAACCCACCACCCATATAAAAGCCAGGACTT GGTTAAAAACTTTCTACCTAACTCTAAGGTGTCTCCCTTGAGTCCATCATTTTCCTCCCC AACTCCAGGAAATACTGTCCTATCCTCAACCTGTGTCTGTAATCTGCTTGCTTGCTTTTG TATACAATTTTATGCATTATTCCTTTAAAAATGTATACACACATACACATGTATATTTAT TTACTTGTTTTATTTATTCATTTATTTTGAGACCGAATTATGAGACGGGTTTTGCCATAT TATCCAGGCTGGTCTCGAACTCCTAGCCTCCGCCTCCCCAAGTGCTGGAATTATAGGTGT GAGCCACCGCAACTGGCCGATTTACTTGTTTTTAATTTATTGAAATATGCAATGTGATTA TTCTGGGCTTTTCTTTGTACTTTTCACTTACTATGAGATCCCTAATATCCATCCATATTG TTGCGCATGACTGCCGGCCATTCATTCTGGCTGCTGCCTGATATTTCAGAGCGTGACCAT CTCTTTCCTGCTAAGCACGATTTCAGTGGTTGCTAGCTTTGCTCTCGTGAACAGCATGGC TTGGACGTTCTTATCCCTGTCTCCTGGTATCGGGGAACCTGCCCCGATATTCACATAGAT TCTTTTCTATTTTTCCTAAGCGTCGGCCAGCTTGAGAAATAAAGGGACAGAGTACAAAAG AGAAAAATTGTAAAGCTGGGCGTCCGGGGGAGACATCACATGTCAGTAGGTTCCGTGATG CCCCACAAGCTGCAAAAACCAGCAAGTTTTTATTAGGGAGTTTCAAAAGGGGAGGGAGTG TGAGAATAGGTGTGGGTCACAGACATCAAGTACTTTACAAGGTAATAGAATATCACAGGG CAAGTGGAGGCAGGGAGAGATCACAGGATCACAGGACCGGGGCAAAATTAAAATTGCTAA TGAAGTTTTGGGCACCATTGTCATTGATAACATCTTATCAGGAGACAGGGTTTTGAGATC AACCGGTCTGGCCAAAATTTATTAGGCAGGAATTTCCTCTTCCTAATAAGCCTGGGAGAG CTATGGGAGACTGGAGTCTATCTCATCTCTGCAGCGTCGACCATAAGAGACGACCACGCC CAGGGGGGCCAGTTTAGAGACCTAACCCCAGGTGCGCATTCTCTTTCTCAGGGATGTTCC ATGCTGAGAAAAAGAATTCAGCGATATTTCTCCCATTTGCTTTTGAAAGAAGAGAAATAT GGCTCTGTTCTGCCCGGCTCACTGGCGGTCAGAGTTTAAGGTTATCTCTCTTATTCCCTG AACAATTGCTGTTATCCTGTTCTTTTTTAAGGTGCCCACATTTCATATTGCTCAAACACA CATGCTGTACAATTTGTGCAGTTAATGCAATTATCACACGGTCCTGAGGCGACATACATC CTCCTCAGCTGACAGGATTAAGAGATTAAAGTAAAGACAGGCATAGGAAAGCACAAGGGT ATTGATTGGGGAAGTGATAAGTGTCCATGAAATCTTTACAATTTATGTTTACAGATTGCA GTAAAGACAGGCATAAGAAATTACAAAAGTATTAATTTGGGGAACTAATAAATGTCCATG AAATCTTCACAATCCACGTTCTTCTGCCATGGCTTCAGCCAGTTCCTCCGTTTGGGGTCC CTGACTTCCCGCAACATCCCGGGGCACACATACAGGAGTTTCTCTTGGGCAACCAAAGGT AGAAGTGGAAGTGCTGGGTCATGGTTATATGAACCTCCCCTCCTCTTACAGCTGGGGAAA CTGAGGCTCAAAGAAGGCAGAAAATTGTGCCTTGGTCCATGTGAATGGCAACGTTGTCCC AACTTGGAACAGCAAGTGGACAAGGAACCAAACATGAGGCTTAGTGAGGAGAGAAGATTA GCTCAAGTTTTCCCCTATGTTGTGGAGGGTTGGATTTGCAAGTGTCTCCTGAGCATCAGC TCTGTGGCAGGTACTGGGGCTGGGGCTGGAGATACAGAAATTGATCAACCTCAGGCCCTG CCCTGGAGGAGTCCTTGGTCTTTGGAGGGGCTGGGTAATGGGAGAGAGGGAGTGCAGAGA GAGAGGGAGACCCCAAAGCAAAACAGCAGTGACTGTGTGGTGGGTTAGTTGTGCTGCTAA TGGGGAGAGGACAGTGGGGGATGCTCAACCAAGGCCGATGGAGGAAGGGGCAATCAGAGA AGGCTTCCTGGAGAAGGTGGCACCTGAGCCTAAAACAGAATAACGAGCTGGAATGCGTAT TAGGGAACTTCAGTTAGGCAGTGGGAGCTCCAAGCTGGATATGTGTGGTGGAGAAGGCAT TCCAGGCAGGAGGAATAGCACAAAGAAAGGCCTGAAAGGGAGGTTCATAAGTTCCTAATG ATGGCGCAGATCTTAGCTTCAGAATTAGGGCATGAGGCCAGGTGCAATGGCTCATGCCTG TAATCCCAACACTTTGGGAAGCCAAGGCAGGCCAATCATTTGAGCTCAGGAATTCGAGAC CAGCCTGAGCAACATGGCAAAATCCTGTCTCTACAAAAAATAGCCAGGCATGGTGGTGGG TGCCTGTAATCTCAACTACTCGGAGGCTGAGGTGGGAGGATCGCTTGAGCCTGGGAGGCG GAGGTTGCAGTGAGCCATGATTGCGCCACTGAACTTCAGCTGGGGCGACAGAGTGAGACT CAGAAAAACAAACAAACAAACAAAAAACAAAAATCAGTAAAGAATTGGGGGATGGGAGGA CAGGATCATTTCACAAACTGTGGCTCATCACACTTTTATGTGACTCCTGCACTGCTGGCT TTTATTTATGTAGATACTTAATGAATTTTTGACTCCCCCCTCACTCTGCCCTTGGCATGG GGGCTTCTCTCCTGCAGCTGGTGGTCTTCGAACTGGAAAACTTCCAGGGCCGTCGAGCAG AATTCTCGGGGGAGTGCTCAAATCTGGCAGACCGTGGCTTCGACCGTGTGCGCAGCATCA TTGTCTCCGCGGGACCGTGAGTACTGGGCGGCGGAGGGGCACACTCTCTGCCACAGTAAA ATGACCACACAACAGTAGCTGCCATTTCTCCAGCATCTGCTCTGTGCCTGCGGCCGTTCG TACTCCTGGCACATACATTATGTCCAATCCTCATATCAAACTGAAGAGGGAGGAATTGTT CTCAATCTCATTTTACGGATGAGGAAACTGAGGCTCGGAGAGGTGATCCAATTAGCATAA GATCACACTGGCAGTAAGCCATGGTTCTGGGCTCTGGAGAAATGCTGCTTCTACTATAGC AAAAACTCTAGCCCGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGG CCGAGGCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACAAGGTGAAAC CCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCC AGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCGGAGCTTGCAGTG AGCCGAGATTGCGCCACTGCAGTCTGCAGTCCGGCCTGGGCGACAGAGCGAGACTCCGTC TCAAAAAAAAAAAAAAAACAAAAAAAAAAAAAACAAACTCTAGCCCATTACCGAGGGCTG AGAGAGGTCAAAGAGTGAAGTGTCCACTCGCTGTCCCCTCTCCTGGGCGTCCAGCTGCCT GGGAGTAATGATAAGCATCTGTGGCACACCCACCAGGTGCCAGGCACTGACTCGGGACCA CACCTAGATGATTCACAGTGCTGTAGGAGGCAGAGGCTATTCTTATGCCCACTTGACAGA TGGAAAGACTGAGGCTCAGAGGGGGTGAGTCTCTTACCCAAGGTCACCTATTGGTAAGTG GCACAGCCAGGATTCAACTCAGGTTGATTGAGTTCATTCCTAAAGCTCTTAATCACCATG CTTCACTGCCTGTTCCTGTCTCTGTGGGTGTCTCTGGGCCTTAGTGACTCCCATATAAAA CAGGGATAGTCATCCTTGGGCAGAGTGGTTGCCCTATGTCCAGCCTGTGTGTGCTGAGGT CAGGGTGGAGGGGCAGCCCCAGGACAAGATCCACGCAGCTCGTTTGCTCTTGTCTCCCCC ACTTTGAAAGCCTGCAAGGGTTCCAGTCATCCTGTATTCTGAGCCCATTCCGAGATGAGC TTTGAGGTCAGACAAGCCTGGGTTTGAGTCCTGACTTCCCCTGTTTGCCTTGTTCAGTGT GCAAGCCTCAGTTTCCCCATCTTTGAAATGGGGAGAAGGATGGCCCTCACCACTCCTCAC AGGATTATGCTGAGGTCTGAGGGAGATCATACAGCATGGGCCTGTTACCTTGTGGGCACC CAAACATGGCAGGTGACTCTGATGGTCACGTACCCACCTCCCTGCCCGGTGAATTTAGCC AACTTATCCTGGAGGCTACCCGGGACCATTTCTACCTCCTGCACCCTCAGTGTGGTCAAC GCAGCCTCAGCTCCACCCTCAGCCCCAAAACCCAGCTGGAAGCAGAAGCTACCGGATGTG GCCAGCATGGGTTTTCAGGCTTTTTTTGGTACCAGTGACTCAAACCCAGAGTATTTCTCC TCAAACAAAGATGCAGCTGGTGTCTGACGTGTGCCTTGGAGCCGTGCCTGATGGGCATGG AAACGGGCCTGTGGTCCGGGGGCCTGGGTCTGTGTGGGCGCTGGCAGGGCCATGGGAAAA AAAGAATGAAGAGGGTGAGGTAGGCATGGGGAAAGTGAGGAGGCCTGCCTGCCTGAAACC CAGGAGACTGCAGCCTGACACCCAACACCATCATGTGACCTTAGGCTGGGGACTTAACCC CTCTTAGCCTCAGTTTCCATATCTTATAAATTAAAATTCCTGCCCTACCCTCTCTCCCTG CTTGCGGGTTGAAATGAGCCATGGGAGATAAGAAAAGGCATAGATATAAACATTTAAAAT TTAGATCCTCACTGGTCCTGCTGAAGAAGATAGGGGAGATTTTAGGGGGACTTGGGCATG GTGGCAAGACCACATCAGTGTCTGTTTTTCCAGAAGCCTAGACCTCCAGTTTCCTTCTCC CTTTAATCAGGAACAGTATTAATTTGGAGGCTTACTCTGTGCTGTATCTGTTCCATGCAT TCCCTCTTTTAGGCCCTCATAATCTCCCAACAAGGTAGATGCAACAAAGTAGATGTATCA TTTCTTCTCTGTTACTAAAGCTTAGCAGGTGTAAGTGCTGCCCAAATGCATGCAGCAAAT GGCAAAGCTTGGATTAGAATTCAGGTCTGTCTGTTTCCAGGGTCTGTCCTCTTAACTCCT ACATGAAACCACCTTCCAAGGCTCCCTTCTTATTCACCCATGCGTCTATCCACCCATTTA TTCATCATCCATCTACTTACCCATGCATCTACCCATTCGTCTATTGATCTATCCATACAT ACATCCATTCTCCATTTATACACACGTACCCACCATGTGTTCTCCATCACCCACCCATCC ATCTATAAATCTATCCATCTACCCACCCATCCATCTACCCATCTAGCTATCCATCAATTC AACCATCCCTTCATCCATCCCTTTATCCATGCATCCATTCATCTGTCCATCTACCCATCC ACCTATCCATCTATTCAACCATCCTTTCATCCACCCATCCATCCACCCATTCATCTGTCC ATCCATCCATCTATTCTCCCATTTATTTCTCTTCTACTCCAGACCAGACAGGGCTGAGGC AAATGCAACTCTATTCTGGGAAGACAAACATATCTTTAATTTACTCCAGTGTGGTTAACT CATCTCTCAGACAAAGACCTGAGGCTCCTGTGATGCATTCTGTCTCAGCCCATGGTGATA GCCCATCATCCTTGTCTCCTTCTGGGGAGAGCAGGGTCCCAGCAGCCCCCTGGGAGAAGA TGCTAGTGTCAGTGTCCCCTCATCCGTCTCTTTTTTCCTAAGAACTCTTGAACACACGGG GAGCAAAGGTCAAGGAGTTCCTTAGTCTCAGCTTTCTCATCTACGGAATGGGGATTGTCT TATCTACCCCACCTGCACTGCCACAATCCCTGGTCCCTGTAACACAAGCTCACTTCTTGT CCTTAATCAATCTTCACTGGGAAAGCCAGGAAAATCTTCCATCTAATTTCAAACTTCTAA TTAGTCCATGTAAGGAACCTAGCATCTTCATAAGCGCTATCACATTATATTACCATAGGT ATCTGAGGGTAGATATTACCATCATTCCCTTCCCATTGCCTCATACTAGTTACTGAGTAT CTCCCGAATACCAGGCCAGTATTTACCCAGCAAGGATGCAAACACCTGTATCAATTTTTC CCTTACCCCTGTACCTCCGAGACTGTCGTTCATTTAATATATTTCATTTAAAATGATCCT GCTAACCACAAATAAACACATTTTAAAAGAACCCTGACACCACTTTTTACAAATGGAAGG CTAGTATTATTTCCTATAAGTAAAAGGTATCCATACAAAATTAACAATAAACACAAAAGT GGTATTATTATGTTGCTATTACACCATTGTCTGCTGGAGGTTCTGGGCTAGTGGTCTTTT CTCTCTTTGTTACAAAAGAAAAAAAGGAGAGATTAGTAAGTGTTAAAGGCACATTAACAT CAAACGAGCCTTTCTCCTAGCTGGCGTCAAGTTTCAAATGTCTATGTGTTCCTTGGCTCC AAGTCCTGATAGTACTTGAAGCATGTATGAACCTTACATCTAGAGAAACAGTGTGCTCAG ATAATCACACACATTTATCTCACTTAATCCTTCACCAACTCCAAGGAAACAGGCATATGA GTGTAGATGAGAAACAAAGGCTCAGAGAGGTAAAGTCACTTGCCCATAGTCACACAGCCT GTAAGTGTCAGAGCCTAAAATCAAACCCAGACATGTTCAGCCCCCTTTGGACTTTCCTAC TGTCCTCAGGGCTGCCTTGCCAGGGGAGAGAGAAAGGCAAGTAGGGAGTGGGGGCTTCTA CTAACCATATGTCTCCTGTCTGCCTCATGGTCCTTCTTGTATCCAGCTGGGTCGCCTTTG AGCAGTCCAACTTCCGCGGGGAGATGTTCATCCTGGAGAAGGGCGAGTACCCTCGCTGGA ACACATGGTCGAGCAGCTACCGCAGTGATCGGCTCATGTCCTTCCGGCCCATCAAAATGG TGAGTGGCTCTCCGGCTGGGGCTGGAGAATCAGCCAGGCGGGGCAGGGCAGGTGTAAGTC TGAGATCTGACAAGGGCAAGAAGGAGATGATGGTGGGTAGGGAGGCGTGGCAGCCTCCGA GTTGTCAAAGGACCGTGGATTCTTGAGCTCATCAATTCATCAGTGTCCTTAACACACTCA CTACATACCCAGCTAGGAACCCTGGGCAAATGATAAGCACAAAAGCTTCCAAGTTAGAGC TAAAAACTTCAGCATCTTCCTTGATTCTCTTGATATCCCTGGCTGCACATTTAGACCTTA CTGGGAGCTTTTTTTTTTTTTTTTTTTCCCAAAGATGGGGTTTTGCTGTGTCCCCCAGCC TGGTGTACAGTAGTGTGATCATAGCTCACTGCAGCCTTGAACTCCTGGCCTCAAGTGATC CTCCCGCCTGGGCCTCCTAAAGTGCTAGGATTACAGCCGTGAGCCACCATGCCAGGCCTG GGAAAACTTTTCAAATTTCAGTGCCCATTCGAAACACCAAACATGCTGGTTGCAGATCAT GCAATGGCTAAGAAGAGGGATATTGTAGCCGGGCATGGTGGCCCATGCCTGTAATCCCAG CACTTTGGGAGGCTGAGGTGGGTGGTTACCCAAGGTCAGGAGTTCAAGACCAGCCTGATC AACATGACGAAACCCCGTCTTTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGCGCAT GCCTGTAATCCCAGCTACTAGCAAGGCTGAGGCAGGAGAATTACTTGAACCCGGGAGCCA GAGGTTGCAGTGAGCCGAGATCATGCCATTGCACTCCAGCCGGGGTGACGGTGCCAGACT CCATCTCAAAAAAAAAAAAAAAAAAAAAGGAGAGGGATACTGTAGAAACGCAGCTTGAAC CTCTTAATAATAAGACAATATACTGAATTAGTTTCTTATAATATTTAACTAAGTCAACTT CCAGAAGATTCAAGGTCAAAATGGTGGCGATATCTCCAAGTGATTCACAGTTTTTTCCAG AATTAAGTTGATGATGAGTCATGAACCAGCTACATCTTACTCACCAATGTTAGTTGCTGA TGGTAACCGACTTTTGTCTTCCATGATGGGAACATTTATAAGAATTTTCATGAATGTGCA TTTGAGGCTATCAAGTGCCAACCACCAGCTGTTTTGACATCACCAAATTTATCTTAATGG ATTATTCAAACAGATCATTCCCAACACTTTTCGCAGAATGTAAGACTGAATTATTTGCCT TCATGATGCACTCTCTGTAAGAATTCACAGATGTCTCTCTCAATCATTGAATGGTTCTTA TATGCCAACCTATGTTAAGGGGTTTGTTTGGAAGAGTGATCAACCAGGGCATTTCCAGTA GCTTCTAGAAGCTTGCTATTCAACATAATAGGCAGTAGCCATATGTGGCCATTGGACACT TGAATTTTGGCTAAATGGAGATGTGTCATAAGTGTAAAATACATATTAGGTTTTGAATAC ATAGTAAAAAAAATTTTAAAGAATGTCAACAATGCATTGATATCATTATATTGGTTACAT ATTGAAATTATAATATTTTAGGTATATTTGTTTAAATAAAATATGTTATTAGAAATGTTT AGAAATCTCAAAGCCTAGACCCCACCCCAGACCAATTAATTCTGAATCTCTAGGGCTGGA ACTCCGGCACTGCTATCTTTTCTATGCCCTCTAAGTAGTCCGTCTGTGCAGCCAGGGCTG AGATCCAACCATCTAATTCAGGGGTGCCCAATATTTTGGCTTCCCTGGCCCACGCTGGAA GAATTGTCTTGGGCTACACATAAAATACACTATCACTAACGATAGCGGATGAGCTTTAAA ACAATTGCAAAAAAAATCTCATAATGTTTTAAGAAAGTTCACAAATTTGTGTTGGGCCAC ATTCAAAGCCATCCTGAGCCACATGTGGCCTGCAGGCCGCAGGTTAAATAAGCTTGGTCT AACCCTTCCTCTCTCTGCCCTGCCACAGTCCTGGTCCAGGCCACCATCATCTCTGACCTG GTCATCTTCAGCTCTCTCCCTGCTGGGTTCCCTGACTCCTTTCCAGCCCCCTGTCGTGGG AAGTTAGAGGGATCTTTTCAAAATAAAAAAAAAAAATAAACCTGACCATCTTCTACTTGA ACCCAGACATTTTGGTTGGCCTGTTTCTATTTTCCTTTTTTTTTTTTTTTTTTTTTGAGA CACATCTAACTCTGTTGCCCAGGCTGGAGTGTAGTGGCACGTTCTGGCTCACTGCAACCT TCACCTCCCTGGGGCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTATAGG TGTGCACCGCCACGCCCAGATAATTTTTGTATTTTTTATAGAGACAGGGTTTCATCATGT TGGCCAGGATGGTCTCAAACTCCTGATCTCAAGTGATCTACCCGCCTGGGCCTCCCAAAG TGCTGGGATTACAGGCATGAGCCAGTGCGCCCAACCAGTTGGCCTGTTTCTGCCAGGCTC TGGTTCTAGGCTCTGAGTGCAAAACTGTGCATCAAACAGACTAGGTCCCTGTCTTCATGG GACTTAAGCTACCCAGGGAGGCAGCTATCAAAAAGCTAATCATAAAAATCCATCTACAAT TGCAAACTGTGGTAGGTGTTACACAAAGGCCATGCAATCTAACTAGGAAAGCAGAAGCAG GAACTGGGGGCTCAGATATTGTTAGAGGTGGGAGTGGTCAGGGGGTCATCAGGGAAGCCA GCTCCCAAAGTTTGGAAACCAACTCAGCCACGTGAAGAGCAGATGGTAAAGCCTTCCAGG GAACAGTGTGTGCAAAACTCCTAGAGCAACGATGGACTGGTGGGACCAAGAAAATTAAAG GTGGCCAACAAAGCTGCAGCAGAGGGAGTGGAGGAAAGAGGGAGGCAAGATGGGAGGGGA GGTGGTGGTGGAGACCAGGGTCTTGTAGGGTCTCATAGGTGGTGGCAAGTTCAGTCTTGA CCCCTCTAGCAGTGGGGAGCCATTGACTAACAACCTTCCCAAGGCCCTCAAGACCGTAAC AGTAATAAGTAATCATTGTTGTACTTTTACCACTGGCTGGTAATTGCACTAAGGGCATTT GTCTTGCCATGCCCCAAAGGGTCCCCTGTGCTTACATCCCTGCCTGGCACCTTGCACTTG CCTTCCTGCACCCTGGCCACACAGATATTGTCTTGCACATTCCCACCTCCCAGCTTTTGC CTATGCCTTCTCTGCCTCAGTGCCTTCCCTCAACCCTCCTTCCCTTCTCAGCTTTGTGCA CTCCTCCTTAACCTCCAAGGTCCCTCTCTAGTGTCACTTCTTCCATGAAGCCTTCCCTGA TCTGCTCTGCTTTTCTCTGGAAGAATTAACCAGTTCTTTCTTCATCTATAATCTCCTACT GGAGTCTTTCACAGAAGGATGCACTTACGTTCTGGGCTCCTCTTCCTCCTAGTGGTGGTG AATAACAGTAGATAATAACAGTAGATAATCACAGCATCCATTTTTAAGCACCAACTACGT ACTGGGTATATTACCTGCCTTTTACATAATCCCTACAACTGTCCTATGCTACAGGCTATG ATAACATGCATTTTAAAAGCAAGGAAACTGAGACTCAGAAGTAGAAAATGACTGGCCTAA GGCCACACAGCTGGGAGTTGCTGGGGCTGGGATTTGAACCAAGGTCTGTGGGTTTGAACC TAGACACTGAGGTCCGGCATCACTCTGCTATTTCCTGTTCATCTCTTTGGCTCTTCAAAC CCTTGGGCCTAAAACAGTGCATGATGACTTTTGAAAAGATGGATGATCCCTGCCCTCAGA AATAACAGACGAACTTTAAAAACAAGATACAGGGTCATGAAAGCATTAAAAATAAGTGCA AGCCAGAACTGAATCATGTGCCCACATTCAAGGGTGGGCCTGGTTGTTTGTTTGTTTGTT TTTTGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGACACAATCTTGGCTC ACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTG GGACTACAGGTGCGTGCCACCACGCCCAGCTAATTATTATTATTATTATTATTATTTTGT ATTTTTAGTAGAGATGGGGTTTCTCCATGTTAGTCAGGCTGGTCTCGAACTCCTGACCTT GTGATCCCACCCATCTTGGCCTCCTAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCC CGGCCAGGCCTGTTTTATAGTTGGACTGAACCGTGAGTTGAGTAGCCATGACAATCCCAC GAAGCAATAGTAACCCCATTCTTTTTTGTTGTTGTTGTTTGAGACAGTCTTGCTCTGTCG CCCAGGCTGGAGTGCAGTGGTGTGATCTCGCCTCACTGCAACCTCCACCTCCCAGGTTCA AGTGACTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACATGTGATTGCACC TGGCTAATTTTTGCATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTT GGACTCCTGACCTCAGGTGATCTACCTGTCTCGGCCTCCCAAAGTGCTGGGATTACAGAT GTGAGCCACCATGCCTGGCAATAACCCCATTCTACAGATGAACAAACTGAGGCTCTGAAG GAGGCAGAGTAAAATGTCCAAGATCACCAGTGCATAAATGTCAGAGGCAGGATTTGTTTT TTGTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTTGCCCAGGTTGGTGTGCA AGTGGCACGATCTCGGCTCACTGCAAGCTCTGCCTCCTGGGTTCACGCCATTCTCCTGCC TCAGCCTCCCAAGTAGCTGGGACTACAGGCTCCCACCACCACGCCCGGCTAATTTTTTTT GTATTTTTAGTAGAGACGGGGTTTCATCGTGTTAGCCAGGATGGTCTTGATCTCCTGACC ACATGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTATAGGAGTGAGCCATCGCAC CCGGCCTAGAGGCAGGATTTGAACCTAGATCTGTGTTCCACCAATGTTCCACGTTTCACC TGGTTTGTAAGAAGCATTTACAAAAGGGCAATTGGTTAAACTCCTGATGGCACAGGGACA CTGCTTAGGAATGAAGTGTTTCTCTGAAAGGTTCTGCCCCTCCCTGGCTGTGTGATGTTG ATCAATAAGCTTGACCTCTCTGAGCCTTTTTGTCCCTGATCATAATTTTAAAAATAATAA ATACTTTTTTTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGT GTAATCATATCTCGCTGCAGCCTCAACTTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCC TTCCAAGTAGCTGAGACTACAGGCATGCACCACCATGCCTGGCAAATTAAAAAAAAAATT ATTTTTTTGAGAGACAGGATCTTGCTATGTTGCCCAGGCTGGTCTTGAACCCTTGGCCTC AAGCAGTCCTCCCACCTGGGCCTCTCAAAGTGCTGGAATTACAGACATGAGCCATGGCAC CCGGCCAATAAATGCATTTATTGAGCACTTGATGTATGCCAGGCATCGTGCTCAGTGCTC TATATGGATACACTCATTTCATCCTCACGAGGACCCTATGACGTGGGAGTTGTCATCCCA TTTTCCTTATGTCTCCTTCCAGACTAGACAGCAGTGGTCCCTGGAGAGTCCCCCAGCAGC CTGAACAGGCTCATCTCTCTCGCTCCACACCCAGAAGGCCCCGCTAAGTTTCTTCTCTTT GTCCCATTTGTACTTCACACACCTGACCCGGCCTCTCTTTCCCCAGGATGCCCAGGAGCA CAAAATCTCCCTGTTTGAAGGGGCCAACTTCAAGGGCAACACCATAGAGATCCAGGGGGA CGACGCACCCAGTCTCTGGGTCTACGGCTTCAGTGACCGCGTGGGCAGCGTGAAGGTCTC CAGTGGAACGTAAGCATCCCTCCTGCCAGGTCCGCGTCCCCTGCTTCAAGCACAGGCAGA ATCAGAGGCTGCTCCCCTTACAGGTTATAACATCAGATTCCTAGAGAAGGCCATGGCCCC TTCCACAGTCTCCCAGTGCTGGTTCCTGGGATCAGCCAACAGAGCTCTATTCCTCTGGGG AATAGAGTCACACTTTGAGGAATTCCAGGTCAGTGTAAACAAATCAGCTCTAAAAAGCTG TTAGATGGAGAAAATAGGAGCTGCTAAGCCTAGTTGGGGTTGAAGGAGTAATCAACTAAA AGGGCCGGCGCTGATGTGGATAGATGAGGCTGGATGCATCCAGGAGCAGGGAATATTCAG GGAAATCAGAAGCTTCTGGGAGAATGAACAGAATGAGTTCTGAGCAGTGAATTTGCATCA TAAGATGGCCCTGACCCTGCTACTGACATGCTGAGGAACTCGAGTGAGCCTAAACACCTC TCTGCCTCTCAGTCTTGCCAGCTAGGCAATGGGCACACAAAATTCCCTGATCCAAGAGTG CCCTTCCTGCTCTGAACGCTCAGGATCTGAAGCTATCAAAACGGAGCCCCATGACCTTAT GTCATGAGAATACATGGAAGGGCCAGATCAAAGGAGTCACTTTATCCATCCCCCTGCCTC CAAATGACCATGCCAGACACCCTTGATCTCCTCTAGGTAAACGTAAGGCTCTGTCTCTCC ATTCCCAGACTTGTTCTGAGCTCCTGTAACACCATCATGGCTATGGCCTTTTTCTTGTTC CTTTCTGCCTCCCTGAAACCTATATCCCTGCCATTCAAGCCATCTGAAATATACGGAGCC TTGTCTGTGAGCCAGGCACTGTGCTAGGTACACTGGGGAAAGCAGCGATGAATACAGCCA AGTTCCTACCTTCAAGGAACTTACTTGGCCTAGCAGGGAAACCCAGATATACCTGTGAGA TGGTGTCCAACAATACTAGGTAAAGAATGGGCCAGCCAGGGCAACTGTGTTGTAGGAGGT CAGAGGAGGAGAGGTTTCTAGGATTTGGCTGTGTATGTTAGGGCAGAGGGCAGGTCAAAG GTTTATCTGCAGAGGATGGAACTTAAACCAGGCTTTACAATATAGGGAGGGGGTCTGGCA GAAGCCTGGAAAGACCCTCTCAGCAAAGACAATGAGAGAAGTTAGAAATTAATCACTGAT GATAACTTCTATTGAGTGCTTACTATGTACCAAGGACTGTGCTAACCACTTTAAATGAAT AACTATTAAATCTTCATAACAAACCAAGGAGGTGGGTGCATTATCATCCCCACTGTACAG ACAGTACATTGAGGTTCTGATACCTTATCCACCTAGATTCTCACAGCTAGTAAATCAATG GCAGAGCTAGGATTTGAACCCACATATATTTGATACCAGAGTATGTGTTCCCAGCTGCTA CGCACTGATGCACTTACCTACAAAGAAAACCAATTTTTTTTTTTTTGAGATGGAGTCTCG CTCTGTCCCTCAGGCTGGAGTACAGTGGTGCAATCTCAGCTCACTGCAAGCTCCGCCTCC TGGGTTCACGCCGTTCTCCTGCTTCAGTCTCCCGAGTAGCTGGGACTACAGGTGCCCACC ACCACACCCTGCTAATTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGCATTAACCA GGATGGTCTCGATCTCCTGACCTTGTGATTTGCCCGCCTCAGCCTCCCTAAGTGCTGGGA TTACAGGCTTGAGCCACCGCGCCCAGCCAAGAAAACCAATTTTTTGAAATAACACTTCCT CTCTTTCATTTGCTTCATTGTTAACCAGTCCCTAAGTCCTATTCTTGCTTCCTTGGATTT GTTCTCTGAGCCCTGCATCATCACGTTTAATGGGATGTGTATTCATATTCCTACCATGCA CAGGCAACATGCTTAGCAAACACTTGAGGTGCATTCTCCATTTGGTCCCCCCCAGCACTC TTAATAAAACCAGGCACCGTGACCATGCTCACTTCCTAGAAAAGGAAACCGAGGCCTATC AGAGAGGCAAAGTCCTTGCCCCAGGGCACAGAGCAGGAAGGGATATAGCCAGGACAGAAG TGAGAGAGCAGCCGACTGCAGGGATCAATGAAGGACAGGCTGGTCTGGCAGGGGTCTGGG TGCCAGGCAACGAGACAGGCTGTCTCCACTCTGTCCTTCTCACTTTTCTCTCAGATGGGT TGGCTATCAGTATCCTGGCTACCGCGGGTACCAGTACCTCCTAGAGCCTGGTGACTTCCG GCACTGGAATGAGTGGGGAGCCTTCCAGCCACAGATGCAGTCCCTGCGTCGCCTGCGTGA CAAGCAGTGGCACCTCGAGGGGTCCTTCCCTGTCCTGGCCACAGAGCCCCCCAAGTGAGT CCACACCTCACTCTGCTACCTTGCCCCAACCCTTCTTCATGTTCAATTATTTCCCCCATT TTTCCCAGGCAAATAAAATTCCCTAAAGCC OMIM ID 600929