Entrez gene ID | | 142679 |
Official gene symbol | | DUSP19 |
Full name | | dual specificity phosphatase 19 |
Aliases | | ,DUSP17,LMWDSP3,MGC138210,SKRP1,TS-DSP1, |
Gene summary | | Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM] |
Location | | Chromosome: 2 Locus: 2q32.1 |
Gene position | | 183943287 - 183964736 Map Viewer |
Gene orientation | | plus |
Gene size | | 21450 bp |
Gene sequence |
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OMIM ID | | 611437 |