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Gene information for CSF1R (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1436
Official gene symbolCSF1R
Full namecolony stimulating factor 1 receptor
Aliases,C-FMS,CD115,CSFR,FIM2,FMS,
Gene summaryThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q33-q35
Gene position149492935 - 149432854  Map Viewer
Gene orientationminus
Gene size60082 bp
Gene sequence
OMIM ID164770