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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KRT80 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID144501
Official gene symbolKRT80
Full namekeratin 80
Aliases,KB20,
Gene summaryKeratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.
LocationChromosome: 12   Locus: 12q13.13
Gene position52585784 - 52562780  Map Viewer
Gene orientationminus
Gene size23005 bp
Gene sequence
OMIM ID611161