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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for A2ML1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID144568
Official gene symbolA2ML1
Full namealpha-2-macroglobulin-like 1
Aliases,CPAMD9,DKFZp686C1729,DKFZp686D2011,DKFZp686G1812,DKFZp686L1821,DKFZp686O1010,FLJ16045,FLJ25179,FLJ39129,FLJ41597,FLJ41598,FLJ41607,
Gene summaryThe alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM]
LocationChromosome: 12   Locus: 12p13.31
Gene position8975150 - 9029379  Map Viewer
Gene orientationplus
Gene size54230 bp
Gene sequence
OMIM ID610627