Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PIK3R6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID146850
Official gene symbolPIK3R6
Full namephosphoinositide-3-kinase, regulatory subunit 6
Aliases,C17orf38,DKFZp666P158,FLJ34500,HsT41028,p84,p87(PIKAP),p87PIKAP,
Gene summaryPhosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. [provided by RefSeq]
LocationChromosome: 17   Locus: 17p13.1
Gene position8770994 - 8706055  Map Viewer
Gene orientationminus
Gene size64940 bp
Gene sequence
OMIM ID611462