Entrez gene ID | | 146850 |
Official gene symbol | | PIK3R6 |
Full name | | phosphoinositide-3-kinase, regulatory subunit 6 |
Aliases | | ,C17orf38,DKFZp666P158,FLJ34500,HsT41028,p84,p87(PIKAP),p87PIKAP, |
Gene summary | | Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p13.1 |
Gene position | | 8770994 - 8706055 Map Viewer |
Gene orientation | | minus |
Gene size | | 64940 bp |
Gene sequence |
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OMIM ID | | 611462 |
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