Entrez gene ID | | 146956 |
Official gene symbol | | EME1 |
Full name | | essential meiotic endonuclease 1 homolog 1 (S. pombe) |
Aliases | | ,FLJ31364,MMS4L, |
Gene summary | | This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants. |
Location | | Chromosome: 17 Locus: 17q21.33 |
Gene position | | 48450581 - 48458820 Map Viewer |
Gene orientation | | plus |
Gene size | | 8240 bp |
Gene sequence |
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OMIM ID | | 610885 |