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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Gpx3 (Mus musculus) (Information is obtained from NCBI Gene database)

Entrez gene ID 14778 Official gene symbol Gpx3 Full name glutathione peroxidase 3 Aliases AA960521,EGPx,GPx,GSHPx-3,GSHPx-P Gene summary This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is highly expressed in the kidney where it may play a role in protecting the kidney from oxidative damage. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 11   Locus: 11 B3-B5 Gene position 54716355 - 54723889  Map Viewer Gene orientation plus Gene size 7535 bp Gene sequence >Gpx3:20221330..20228757:Length=7428 CGCGCCCCAGCCCGCCATGGCCCGGATCCTCCGGGCATCCTGCCTTCTGTCCCTGCTCCT GGCCGGGTTTGTTCCGCCGGGCCGGGGACAAGAGAAGTCTAAGGTGAGTGAACCTCCGGA GCTCAAGAAGAGTCCATGGCACCCAGGTGTCCACTGCGCGACTGGGAGAGCCACTGCTTC CCCAGAGGCACCGAGAGCCTCACTTGTAACCCTCGGTCTCTGCGCTCTTCCAACACAGAC CCGCGTGCTTCAGAGGGCAGTACTAACCCAGGAGGGCAGTCTTTCCCGAGTTTATACATT TTCTTCCACTGTCATCTTGGGGTCGCTGGTGGCCACAATCCTGAAAAAAAATTGCCGGGG AAGAGGGTGGGCCGATGGTTTCTTCACTCATCCCAGGGCGCTGGAGGCAGAGATCTGTGA CAGGAAGAATTTTTATTTGGGGGCGCATCCCTTTCTGGGCCTCAGTTTCTCCATCAGCAG GGCGTAGCTGGAGAGGATGGCTGGAAGGCTATGGAACCCTGCAGTTGCTTTCCCTATTCA CAGTTCACTGGCCTGCCATGCATGGAGCAGACACTGTAGCTAGAGAAGCCAACCCAGGCC AGGAAGTCTTCTGGAGCTTCATCTCTCCTAGTCTAGCTGTGGTACCCTGAACTGGAATAG AAATGGCGAGCCTGAGGGCAGATGCCCCGGCATGCTTATCTTCTTGGTCAGGCCTGTGCT GGGTGGGCTCTGTAGGCCTCTCCTCTTCCCTAGGGTGAGAATGCAGAAAGCATGAACCCA AAGAAAGAGACTGTGGTCCCCAACTTCACACACACCATGCACACCATGCACCCCTGCACA CTTGCATGCGTGGGCACAAAACTGGGTAGGCTCTAGCTTTGAGTTTCTAAAATCCTCAGG GTCTTCCTTCTAAGATCTTGTATGTCCGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG AGATTGATTAGGGGGTGTGGTGTGGAGATGGGGTGGGGGTGGACGGGGGCACTAGCCCTG TGCCTTTAGTGTGGGAACTGCTTGGGTTGGGGGTTGAATCCTGTCCTGAGGAGGCTGCAG GAAAGCACACTGGCCTTGTGCTGTCCATAGAATGAAGGAGAGATGGGTGAGTTCAGAGGG AAGAGAGAGAGCAGTCTAGAAAAGTCTTAGGGTGTGGTGTTATCTTATCTCATAACTAGC TGAAGCTTCTGGCTCCTCACAGCCCAGGCATGCCCATCTGAGCTCCCAGGTCCTTGGAGT TAACACATTACAGCTCTGGCTTCTGGGATTCAACTGCTTGCCTGGATCCAACTTCAGAAC AAGGGAACAGGGAGGGGACGTGTGCAGACCCAGTGTGATAAAGCCACTGAAAGATGTCCT CTACACTCAAAGGGAGGGGCAAGGACAGGGAAAGCCTCTGTCTGGTCCAGGTTACAGCTG CAGAAGGCTTTGCATAGCTGTGGACTACCAGCTGCTGACGTGGCATCCTAGTAACCACTG GTTTCTAGGTGACTGACTGCACAAGGCAGAGAGCATCATGGGAGCACAGGCTGACGTCAA GGCTGAAAGGCCTTAAGTGGACCTGAATCCCACTCCATCTTACAGTTGACAGGCTGGAAT CCTGAGAAGGGGGAGGGATGGTCACACACTGCCAGAGGCCCAGCTGGGTCCAGCTGCCAT CTCCAACCTCTCAGACCTGTCATGCTCCCAACATCTCACCAATGGGTGTAGGAAGATGGA ATAGGGAAGACATGGACCAGTAGTAGCCCTAGGCATCCAGGAAGCTTAGCTCAGTGTATT CCCCCCCAGCCCCACCCCTTTTGTTCCTCGTTCCCTTTCAGTACTCTTCTCTGGCCTCCC TGGTGGAGGAATAGGGCTATGGGATTCTATGAACCCAGAGGAAGGAAGCTGGGGGTGGGG GTGGGGTTGGGGACTCAATTGGTGAGTATAATCTATGGCTCATTTATCAAGACCACCCTC CGACCTATGCTAGCCTGGGCCCCCAGCATGAGCCCTATTCTCCTCCCATAGAAAGCATGG CAGTTGCCATTATTCATTTCTTAGGGCAGCTAGCACACAATTAAGGCCTCTCTGTACTAT GACCCTTCCAGGCCTTTGGCCCTTGCTGCAGGTAATCTCCATGTCCTGCTGGCCCAAGCC TGTTTTCATCTGTCAGTAGTTTCTCAAAGTCATTTTGAGTGTTGGGATGACAATTCGATG AGTAAAATCATTGTTATGGAAGCAAGAGGATCTGAGTTCAAATCCCCAGCATCCATGAAA AAGCCAGGTATGGCCACACACGTGCCAACAATGGTGAGGTGGTGGGGCAGAGACTGGCAG ATTCAGGAGCTCATCACCAGCAGAGTCAAACACTGAGCACAGCTGACAGGGTCAGCAACA TGGCTCTGGGGTGACGATGCTTGTAACCAAGCTTGAGACCTGAGTTTGATTCCTAGAACC CACATGTAGGAACTCACTGGGTCTTCCCAGCTGTCCTTTGATCTCCACATGCTGTGACAT CCTCCCCCAAATAAGTGAATAAATGTAATGAAATAATTTAATAGAGAAACTCTCACGATT TTCTTCTTTGGCTTCCACATGTAACTGGCTAGACACACAGCCAAACAAAACAGCAACAAA CACACACTTTTGAGAGGCAAATGGAATTAACCTCTCAGACCAAAGCCCAAAGGATTAAGA TGGTTTGCTCAGGGCCACACAGCCGGTAAAGATAACCGAGTCTTACTCAAGGGTCTCCTC ATGTCCCCTTCCTTAAGACTATCCGGAGAAGCTGGACCCACGGGTGTTTCCCATTATTCA GTGAGCCTCTGGGATCTCCTCCCCACATCTGAGATTCAGCTTGGTATGAAGGTGAAGCGC CATGCAGGGAGGTAGCAGGGTTGTATCTCACTGTTTTTACTATGTTGCTCTTGTTGAGGC AAGGTATCTCAACGTAGCCCAGGCTAGCCCTAAACTTTCCACCTCCTGTTCCAGCCTCTG ATGCTGGCCTTACTGATGTGTGACCCCCAAGCCTGAGGCTGTTTGCCTTTTAGGGTGGAA GTGATCTCAGCTGGGGCTTCAGAAGCCTGGGGCAGGGCTGTCCAGCTGAGCATTCAGTCT AACACTCGCAGTATTTAGACTCCCGGAAAGCAGGGACTTTGCACCCCAGCCAGGAGAGCT GTCAGCTGTCAGGGATGACCCAGCAAAGGCAGCCAGGCTCACTCGGCTGGCTAGCCAGGC CTGCAGTGATAGAGGCATTCCACTGTACCCCACTGGGGCACCTGCCCTGCTGCCTGGATG ACTCCTTCACCCAGTGAGGCTGAAGGCCTTGCTTGGGCAGCACGTTTTCTAGACCCAGAG GGAAGAGTACCTTCCTATGAGGCTCTCCCACTTCAAGAGGAGCCCTGGAGTTTTGCTGTC CCTGTTGGGGGTGAGGTGGGGTGGGGATGGGTCCCTTTCCTCCTGTTTCAGTTAAAAATA GCTAGTCCAGCGTAATAGGGAGGCTGGGGAGGAGAAATGATCAAGATAGCACTGAGCTGG TGGCAGGGCTCGAGGGGAACCTGGGTACTCTGGCACACCCCACTGTGCCCTATGCTCCTT CCCTCATTCTCCTGGAGGTAGCCTGTGGAGTGTCAGCTGGACAGACAGGAGGGTGTATGG GTTAATACCCACTGTGTCTTCACTCTGGGTGTCACAGTGAGGCCTTGTGACAAACTGTTC CATACTCCGGGGCCCTGTTCCCACATCCCTGCTTCCTCGAGCTCTGACTCATTCCCAACA TCCTGACACATCCTTTCTGTCCAGTGTCTCCTTCCTGGTCACCTAGCCCAGGCTTCCTCA TGCTTGTCTGGACTTCGGTAGCAGCCACCCAACTGTGCCTCTCAGACCAACCTCACCCAA CTGCCTAGGAAATATGAAAGTGGTTTCTGCTAACTTCAGAGTTCCACAGCACCCAGTAAG CAATTAATGCAAATACTGAGTGCTTACTGGGTCCTCAAGTATCTCAGTTATGGGAGATGA GGAATTAGGAGACCTCAGGTTTAGTCCAGTTCCAGTTTTTGTTGTCCTGGGTAAGTCACT CTCTCCCTGCTGGCAATCATCCATGACGGGAAGGTGGAGAAATGTCCTAAATGTGTCCAC TCTAACAGCTCCCTTCTTCCACCTTCTTCTCTTCCAGACAGACTGCCATGGCGGTATGAG TGGTACCATCTACGAGTATGGAGCCCTCACCATCGATGGGGAGGAATACATTCCTTTTAA GCAGTATGCAGGCAAATATATCCTCTTTGTCAACGTAGCCAGCTACTGAGGTCTGACAGA CCAATACCTTGGTAAGAGCTCCCTCAGGACTTGCTACTAAATCTGGACCCAACTCTGTCT TTTGGGGACACTTTAATAACTGTGAGGTACAAGGGGGAAAGGGTGGTGGTGACGCACAGG CCCAGGTTTGTATCCCAGCTCCATTGGATTTCATACTTTCTGGAGAGCATTACGTAAGCC TGAGGTGTGATGGTCTTTGTACTCTAGCAAGTTCCCGGCTACCTTTCTTTACCCTAGGGC ACCTCAGATACCTTGACCGTGTGCCTGCTTGCTTCCCTTGTCTGCAGTAAGAAATGACAG AGGTAGCTGCAGCTCACTGGCTGAGAATGCCTCCTCTCCCCCTAGCCCCCACTAGCATGA GCCCGTCTCTTGGCTTCACTCTGGAGAAGAGTCCCGCTAGCTTGAAGCTCTGGAGATTGA TGGGGAAGGATGGGATCCTGAAGTGGTGGCATCCAACAGTTCATTCTTTTTGGTTGTTTA TTTTCTCATAACAGGGTTTCTGGGTAGCCCTGGCTGTCCTCAGACTTGCTCTGTGGACCA AGATGGCCTCAAACTCAGGTCTGCTTGCCTCCTAAATGCTGAGATCAAAGGTGTGCGCCA CCACTGCCCAGCTCAACAGTCCATTCTCAAGCAAATGTTAAAGGCAGACTAGCTCAGCCC TGCTCTTAACTCAGTATCCATCCAGGAAAGGGCACCTAGGGTCAGGGTGTATAAACGAGG CTGGCAATGGCTTAACCCGGTATCTGACTGGAACCATGTCTCCTTAATGTCTCTATCCTG TCTTTTCTTCTCAGTGAGGGCAAACAGAAGCCTAAGGGCCAAAGCCTGATGGCCCAAGGG CAAACACTTTGGGGCCAAGCAGACCCAGGCCACTTGGCTGGCACCTGCAGGAGAGTTCCT GGGCTGGGTGATGGCGCTGCCTCTAATTCCAGGGGTCCCAAGGGAACTGGCGAGCTGGCC AGGGCCTCCCCTGGGCTCCTGAATTCCCAGATGAGAGGGATGTGAATACTGCCCTCCAAT CACCCGAAGAAAGTCCTCAGCCACCTGCCCAGGGGCTAAGAGACCCAGGCAGCAGGTGTG ACTACCCATATACAGAAGCATACTCCTGACTTCTCTCCCAAACCGCCACTGCCCCCAGAC TGGAGGCTCAGCCTTGCCACTGACTCTGTCACCCCGGGAAAGTCCTCCCTTCTTGGGCCT CACAGGTTCCAGCAGTCTGGAGGGTGTTGAGGCAGGTTCTTCACCTCTTCTCTTCTCTCT CCCTCGTCAAGAACTGAATGCACTACAAGAAGAACTTGGGCCATTTGGCTTGGTCATTCT GGGCTTCCCTTCCAACCAATTTGGCAAACAGGAGCCAGGCGAGAACTCGGAGATACTCCC CAGTCTCAAGTGAGTTCTCATGGCTGGAGACGGCAGCCTCTATGGGGCAGAGGCTCAGGG GCTGCAGATATTGGTTGACGGTCTCCACGTCAGCCACTCAGTTACTCCCGCTCCCCCATC CTCACCCCAGTTTGGGGTTTAATGGAATGAGGGGGAGGGTACAGGAAATAGGAGGCTGTG GGTAACTGTCTGGGCAGCACATTGAAGGGTAGAGATGTGGGGTGGGTATAGAGAGGGGCT GAGATGGCAGATACACACTGGGCCTATGTATGTCCATGCAAGTCGTGCGCTTGATAAAGG AGATTCCCAGCCCCCTTCCCTCAAGTCTCTTCATCTTAGTTCTGAGCTATGTGTGGCTGC TCTGGACTCACTCAAGTACACTCCTCCCAGGTATGTTCGACCAGGTGGGGGCTTTGTGCC TAATTTCCAGCTCTTTGAGAAAGGAGATGTGAACGGGGAGAAAGAGCAGAAATTCTACAC TTTCCTGAAGGTGAGAGTGGGTAATATGGAGGAAGCTCCCCTTAGCGGCTTAGGCCCTGG CCCACAGGAATGTCTTGGCATTGGTCTAGTAGACCCATGAGAGGGCTTGGCAGACCCAGT CCTATCACCCTACTGCAGACGTAAGACAGGGTCCACAGCCTTCCAGTCAGCATAGAGATG GACGGACAGTCAAGTGTTCTTGTTCCCGAACTGGGCCCTTCCCTCAGTGCCAGTTTTCTC CCTGGAAGGGAGGGGAGGTCAGGAGGAGCCTCAAGTCAGACTAACGCCCCTCTCACCCCT GCTCCAGAACTCCTGCCCTCCCACTGCAGAACTCCTGGGCTCACCTGGCCGCCTCTTTTG GGAACCCATGAAGATCCATGACATCCGCTGGAACTTTGAGAAGTTCCTGGTGGGGCCAGA TGGCATACCGGTTATGCGCTGGTACCACCGGACCACAGTCAGCAACGTCAAGATGGACAT CCTGTCTTACATGAGGCGGCAGGCAGCCCTGAGCGCCAGGGGGAAGTAACTGATGCCCCC ACCCTACCCCTACCCCCTGCCCATCATGCAAGGGCCGAGGAGGGGCTCTTCAGGAAGGAA GCCACATTCCCAGTCATTCTACCCCCACCCCAGATTCTCTTTCTTATTACATAAAAGACA AGCCTGGCACAACTGTGTGTCTGAACCACTGTGGACACGTGACAATTGTCCCAGTGTGTG CATGGCTACACAGCCACGTATCTGCCTGCTTGAAACCCAGGGATGGTCCATCTGTGTTTA CGGCTTGGCACAACACCCTCATATTTTTTTCAGCTTTCTGTTCCAAATGAGCCCAAAGGA AACACAAGTTCTAGGTCCAATGGTTCTGCTCAAACCTGAACATCATTCTTGGGGCCAGCA TCTCCCACATGCCCACACTACACACCACCAGCCTCCTTCTTCCTTCCTGAAGGACCCTCC TGAGCCCCCAAGCCCATCCCACAGTGCTCCTGAGACCAGCCAAGACAACTGTGAGCGCGA TGGCCGTGTACCCCAGGTCAGGGGTGGTGTCTCTATGAAGGAGGGGCCCGAAGCCCTTGT GGGCGGGCCTCCCCTGAGCCCGTCTGTGGTGCCAGCCCTTAGTGCATTCAGGCTTAGGCT CCCAGGCAGGGACACTACCCCCGCGCCTCTGGAGGACATGCTATCCTCTCACTCTGTCCA CTGGTATCTCAACACCCCCATCTGCCCAGTAAAGGTCTTTCTGCAGCA