Entrez gene ID | | 148 |
Official gene symbol | | ADRA1A |
Full name | | adrenergic, alpha-1A-, receptor |
Aliases | | ,ADRA1C,ADRA1L1,ALPHA1AAR, |
Gene summary | | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8p21-p11.2 |
Gene position | | 26722922 - 26605667 Map Viewer |
Gene orientation | | minus |
Gene size | | 117256 bp |
Gene sequence |
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OMIM ID | | 104221 |