Entrez gene ID | | 14805 |
Official gene symbol | | Grik1 |
Full name | | glutamate receptor, ionotropic, kainate 1 |
Aliases | | A830007B11Rik,D16Ium24,D16Ium24e,GluK5,Glur-5,Glur5,Glurbeta1,MGC25101 |
Gene summary | | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16 C3.3|16 58.0 cM |
Gene position | | 88290503 - 87896142 Map Viewer |
Gene orientation | | minus |
Gene size | | 394362 bp |
Gene sequence |
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