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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ADRA2A (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 150 Official gene symbol ADRA2A Full name adrenergic, alpha-2A-, receptor Aliases ,ADRA2,ADRA2R,ADRAR,ALPHA2AAR,ZNF32, Gene summary Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq] Location Chromosome: 10   Locus: 10q24-q26 Gene position 112836790 - 112840665  Map Viewer Gene orientation plus Gene size 3876 bp Gene sequence >ADRA2A:63641254..63645129:Length=3876 CAGCAGCAGCTCCAGCTCGGTGCAGAAGCCCAGCAGCCGGCGTGCCGCCGCCCGGCCACT CCAGCGCCTTCTTCCCCGCCTTGCGCTCCTGCCCCAACTCGCGCTGTCGTCGGACCCCGG CCCATCCAGCAGCGCTCGGCGCCCACCAGGCGGACGCCCAGGAGAACCCCTGCCTCCGTC GCGGCTCCTGGAGAGCTGATCGTTCACCTGCCCCGGCCCGCCTGAGGACGGGGGTGCCTT CATGCGGCCCCCACACTCCTCACCCCGCCGCCGCCGCCGTCCCGGAGCTCCGCACAGTGT GCCCCAGCCCCAGCAGGGCGCACAACTTTGGAAGTCTCGCGGCGCTCCGAGAGGCGGCAG AGTCCGCGCCCCAGCCCCGGGCCGGGCCGGGCCAGAACCGCAGCGTCTGGGGGAAGCCAG AGAGTCGGTAATCGCTTCGGGGATGTAAGGCGACAGACATAGGACCCCCGAGCTCGCATC AGCACCCTTCGGCTGCCTCCCGGGGTGGGGGCGGGCCCCGCACACGGTAAGACCTCTTGC TTTCGCTCAGGCTCAAGATTCAAGATACAGATATTGATATGTATATATATATTTAATTTC CTGTCATCCTTCCAAGTTATCAGGCCACCGATGATTTTTGTTCTCCCTTCTTGAAGAATA AATCTCTCTTTACCCATCGGCTCTCCCTACTCTCTCCCGCCGCTTAGAAATAAAACTTGG CTGTATTAGGAGCTCGGAGCAAGAAGGCGCCCACCGAGAGCGTCTGAAGCGCGAGCCAGG CGCAGTTCGCGGGACCCGGGCCATGGGCCGCTAGCGGTCCTCCAGTTCGGGCCCGGCCTC CCTGCGGCCCCCTCCCTATGTGAGCCGCAGCCAGGCGAGCGGGGCGCCGGAGGAAGAGGA GGACCCACGGGCGCCGGGCCGGAAGGCAGCTGGCAGCAGGCCCAGGCCAGCGGGCGCCCG CGTTCATGTTCCGCCAGGAGCAGCCGTTGGCCGAGGGCAGCTTTGCGCCCATGGGCTCCC TGCAGCCGGACGCGGGCAACGCGAGCTGGAACGGGACCGAGGCGCCGGGGGGCGGCGCCC GGGCCACCCCTTACTCCCTGCAGGTGACGCTGACGCTGGTGTGCCTGGCCGGCCTGCTCA TGCTGCTCACCGTGTTCGGCAACGTGCTCGTCATCATCGCCGTGTTCACGAGCCGCGCGC TCAAGGCGCCCCAAAACCTCTTCCTGGTGTCTCTGGCCTCGGCCGACATCCTGGTGGCCA CGCTCGTCATCCCTTTCTCGCTGGCCAACGAGGTCATGGGCTACTGGTACTTCGGCAAGG CTTGGTGCGAGATCTACCTGGCGCTCGACGTGCTCTTCTGCACGTCGTCCATCGTGCACC TGTGCGCCATCAGCCTGGACCGCTACTGGTCCATCACACAGGCCATCGAGTACAACCTGA AGCGCACGCCGCGCCGCATCAAGGCCATCATCATCACCGTGTGGGTCATCTCGGCCGTCA TCTCCTTCCCGCCGCTCATCTCCATCGAGAAGAAGGGCGGCGGCGGCGGCCCGCAGCCGG CCGAGCCGCGCTGCGAGATCAACGACCAGAAGTGGTACGTCATCTCGTCGTGCATCGGCT CCTTCTTCGCTCCCTGCCTCATCATGATCCTGGTCTACGTGCGCATCTACCAGATCGCCA AGCGTCGCACCCGCGTGCCACCCAGCCGCCGGGGTCCGGACGCCGTCGCCGCGCCGCCGG GGGGCACCGAGCGCAGGCCCAACGGTCTGGGCCCCGAGCGCAGCGCGGGCCCGGGGGGCG CAGAGGCCGAACCGCTGCCCACCCAGCTCAACGGCGCCCCTGGCGAGCCCGCGCCGGCCG GGCCGCGCGACACCGACGCGCTGGACCTGGAGGAGAGCTCGTCTTCCGACCACGCCGAGC GGCCTCCAGGGCCCCGCAGACCCGAGCGCGGTCCCCGGGGCAAAGGCAAGGCCCGAGCGA GCCAGGTGAAGCCGGGCGACAGCCTGCCGCGGCGCGGGCCGGGGGCGACGGGGATCGGGA CGCCGGCTGCAGGGCCGGGGGAGGAGCGCGTCGGGGCTGCCAAGGCGTCGCGCTGGCGCG GGCGGCAGAACCGCGAGAAGCGCTTCACGTTCGTGCTGGCCGTGGTCATCGGAGTGTTCG TGGTGTGCTGGTTCCCCTTCTTCTTCACCTACACGCTCACGGCCGTCGGGTGCTCCGTGC CACGCACGCTCTTCAAATTCTTCTTCTGGTTCGGCTACTGCAACAGCTCGTTGAACCCGG TCATCTACACCATCTTCAACCACGATTTCCGCCGCGCCTTCAAGAAGATCCTCTGTCGGG GGGACAGGAAGCGGATCGTGTGAGGTTTCCGCTGGCGCCCGCGTAGACTCACGCTGACTG CAGGCAGCGGGGGGCATCGAGGGGTGCTTAGCCCCAGGGCACTCAGAAACCCGGGCGCTG CCTGCTCTGCGTTTCCTCGTCTGGGGTGGCTCTGCAGCCTCCTGCGGGCGGGCGTCTGCT GCTCCTACAAGGGAAGCTTCTTGCTGCCAGGCCCACACATCCCCAGTTGTTGGTTTGGCC ACTCTTGACCTGGAGCCATCTTCCTAGTGGGCCACCCCTAATCACTATTGCTTCCTAAAG GTATTTTCACCCTCTTCGCCTGGTACAGCCCTCACAGCTCTTCAGAGCAAGCACTGGACT ACAAGGGCATGGCTCACAAAAGGTTAATGGATGGGGGTTACCTAGCCCTGGCTAATTCCC CTTCCATTCCCAACTCTCTCTCTCTTTTTAAAGAAAAATGCTAAGGGCAGCCCTGCCTGC CCTCCCCATCCCCCGCTGTAAATATACACTATTTTTGATAGCACACATGGGGCCCCCATA TCTCTTGGCCTTGGTTTTGATGTTGAAATCCTGGCCTTGGGAGAGATGCCTTCCAGGCAG ACACAGCTGTCTGGTTCAGGCCAAGCCCCTTTGCAATGCAAGCCCTTTCTGGTGTTATGA AGTCCCTCTATGTCGTCGTTTTCACCAGCAACTGGTGACTGTCCCTTCGACACGGACCTG CTTTGAGATTTCCTGACAGGGAAAAGATTTCTGTCCATTTTTTTCCTGTGCCTAACAGCA TAATTGCCTTTTCCTATGTAAATATTATGATGGTGGATCAAGACATAAGTAAATGAGCCT TTCTGCCTCACATCAGCCCTGTGTATAAAGCCATTATTCTCTGATGCACTGTTTGCCCCA GTAACTCACTTTAAAACCTCTCTTTCCAGTGTTCCCTCTCTCCCTCCAGGGCCACTGCTT GAAGAAGAATATGTATGTTTCTATCTTGTATGTCTGTGTGCCCCTCCTGCCCCGAAAGTG CTGACTATGGGGAAATCTTTTAGCTGCTGTTTTTAGACTCCAAGGAGTGGAAATTATGTG GAAGAAGCAAACCTGATACAATTTGCCCAAGGTAAACAGTTTGAAAAGACAAATGGGCCT GCCAAACTGTACAGTTTCTTCCCCAAGAGCTGTTAGGTATCAAAATGTTGTCCTTTCCCC CCTCCGTGCTTTTCTGGTTGAGATCATGTCATTGATGAACTGCCAAAGTCAGGGGAGGAG GGCAGAGACTTTGTGTTTACATCTGCATTTCTACATGTTTTAGACAGAGACAATTTAAGG CCTGCACTCTTATTTCACTAAAGAAAAACTAATGTCAGCACATGTTGCTAATGACAGTGG ATTTTTTTTTAAATAAAAAAGTTTACAGATCAAATGTGAAATAAATATGAATGGAGTGGT CCTCTTGTCTGTTATCTGAGTTTTCAAAAGCTTTAAGACTCTGGGAACATCTGATTTTAT GGATTTTTTAAAAATAAAAAATGTACATTATAAAAA OMIM ID 104210