Entrez gene ID | | 150290 |
Official gene symbol | | DUSP18 |
Full name | | dual specificity phosphatase 18 |
Aliases | | ,DSP18,DUSP20,LMWDSP20,MGC32658,bK963H5.1, |
Gene summary | | Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM] |
Location | | Chromosome: 22 Locus: 22q12.2 |
Gene position | | 31063872 - 31058039 Map Viewer |
Gene orientation | | minus |
Gene size | | 5834 bp |
Gene sequence |
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OMIM ID | | 611446 |