Entrez gene ID | | 150962 |
Official gene symbol | | PUS10 |
Full name | | pseudouridylate synthase 10 |
Aliases | | ,CCDC139,DOBI,FLJ32312,MGC126729,MGC126755, |
Gene summary | | Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM] |
Location | | Chromosome: 2 Locus: 2p16.1 |
Gene position | | 61245365 - 61167548 Map Viewer |
Gene orientation | | minus |
Gene size | | 77818 bp |
Gene sequence |
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OMIM ID | | 612787 |
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