Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PUS10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID150962
Official gene symbolPUS10
Full namepseudouridylate synthase 10
Aliases,CCDC139,DOBI,FLJ32312,MGC126729,MGC126755,
Gene summaryPseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM]
LocationChromosome: 2   Locus: 2p16.1
Gene position61245365 - 61167548  Map Viewer
Gene orientationminus
Gene size77818 bp
Gene sequence
OMIM ID612787