Entrez gene ID | | 1512 |
Official gene symbol | | CTSH |
Full name | | cathepsin H |
Aliases | | ,ACC-4,ACC-5,CPSB,DKFZp686B24257,MGC1519,minichain, |
Gene summary | | The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15q24-q25 |
Gene position | | 79237420 - 79214092 Map Viewer |
Gene orientation | | minus |
Gene size | | 23329 bp |
Gene sequence |
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OMIM ID | | 116820 |
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