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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP2A6 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1548 Official gene symbol CYP2A6 Full name cytochrome P450, family 2, subfamily A, polypeptide 6 Aliases ,CPA6,CYP2A,CYP2A3,P450C2A,P450PB, Gene summary This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.2 Gene position 41356352 - 41349443  Map Viewer Gene orientation minus Gene size 6910 bp Gene sequence >CYP2A6:complement(13617661..13624570):Length=6910 ATCTATCATCCCACTACCACCATGCTGGCCTCAGGGATGCTTCTGGTGGCCTTGCTGGTC TGCCTGACTGTAATGGTCTTGATGTCTGTTTGGCAGCAGAGGAAGAGCAAGGGGAAGCTG CCTCCGGGACCCACCCCATTGCCCTTCATTGGAAACTACCTGCAGCTGAACACAGAGCAG ATGTACAACTCCCTCATGAAGGTGTCCCAAGGCAGGGAGATGGGTGGCACGGGGTGGGGG CTGCCTAGTTGGCTGGGGCTTTGTGGCAGGGGGTTGACCAGTGTGGACCAGAGTCTTAGG AAATGGAGTTTTGGAGTTTCAGCATCAGAAAGACAGGATCTTGGGATGTCCAGCTCCCTG ACTGTGAGAACCTGGGTGCGAAGCATCCCAGCACATGACATCTCGGTGCTGGGCCCCATT CAGAGTGGAGGCTTCTCCCTCTAACCACTCCCACCCACCTCCATCAGATCAGTGAGCGCT ATGGCCCCGTGTTCACCATTCACTTGGGGCCCCGGCGGGTCGTGGTGCTGTGTGGACATG ATGCCGTCAGGGAGGCTCTGGTGGACCAGGCTGAGGAGTTCAGCGGGCGAGGCGAGCAAG CCACCTTCGACTGGGTCTTCAAAGGCTATGGTGAGGGGGTGCCCAAGAGGGGGAAGGTGG CCAGGTGGACACGAAGGTCTCAGTGTTCCCAGCCTTCTCCCTGACTCTCCTGCCAACTGG AGGCTAAGGCAGAGTCCCCAGTCTGGTCTTCCCTCCCCATCTCCCTTCATTGTGGCCTCT CCATGTGTATCCCTCACCTGTCTCCAGCGTCCCTGTCCTGATTCCTCCCTGCCTCTCTCT GCCCCACCTCCTTATTCTCTCTCACTGGAGTCTCCTCTTTCCCCTCTCTCTCCATCTCTA AGGACATCCTGGGTTTCTGTTTTCCAGCCCTGGTTCTCTGTCTTCATTTGTCTTTTTGTC CCTCTTAGCTTCTGGGCTTCTCTGTGTTTCTCATCTCTCCGCATCCCTTTCTCACTTCTT CCTCTGTCTTAGGATTTCAGGGTATTCCTACTTCCACATCTTCAGCCTCCATCTCCTGGT AACAGTCTCTCTTCCTTCCAGACCCTCTCTGTTTCTATCTCAATATTTTTCTCTCTTCTC CAGCTCAGCTTAAGAATCTTTCACCATTTTTATTTCCTCCTCCCAGATCTCCCCATATCT CACTTCCCCTCCCTCCATCCTCTTCCTCCATCACTCTCTTTCTCTCCCCACTTCCTTCCC TTCCTCCATGGAGTGTCCCCTTATCCCTCTGTTTCTATGTGCATCTCTCTGTCTGGCCTT TCTGTTTCTTTTCTGATTGTCTTATTCTTTAAACCTGGTCTCTCTCTCTCTCTCTCTCTC TCTCTCTCTCTCTCTCTCTCTCCTCTCTCTCTTCTCTCTCTCTCTCCTCTCTCTCTTCTC TCTCTCTCTCTCTCTCTCTCCTCTCTCTCTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC TCTCTCTACCTCGACATCGTGTTTCTCTGACTGAGTTTGCAGCTCTGCTGGGCAATGGCG CTGAATCCATCTCTCTCCCACCCTACTCCCTCTCTCCTCCACCCTTGGGGAGCCCCTTGG AGCTGCTCCGCTCCTGCCCCTGCCGCCCCCTGGCCTGTCTCCATTCCCGCGTTCACCTCC CCAGGCGTGGTATTCAGCAACGGGGAGCGCGCCAAGCAGCTCCGGCGCTTCTCCATCGCC ACCCTGCGGGACTTCGGGGTGGGCAAGCGAGGCATCGAGGAGCGCATCCAGGAGGAGGCG GGCTTCCTCATCGACGCCCTCCGGGGCACTGGCGGTGAGCAGGGGACCCCGAGTGCGGGG GCAGGAGAAGGAAAACACCCAGGACGAGGAACCCGCGCGCGTTCTGCCTGGGGATGGGGA CTAGGTGGGGAAAGGCGCCCGCACTTCCAGCCCTGGAGTCTGGCGCTGGGAATTTGGCTC AACAAGGCCCTGCCTCCTGGAATTCTGACTCTCCTCAGACCTCTGAGTTGACTCTCTCCC CAACCCCCTTCTCCCGCCATACCCGCAGGCGCCAATATCGATCCCACCTTCTTCCTGAGC CGCACAGTCTCCAATGTCATCAGCTCCATTGTCTTTGGGGACCGCTTTGACTATAAGGAC AAAGAGTTCCTGTCACTGTTGCGCATGATGCTAGGAATCTTCCAGTTCACGTCAACCTCC ACGGGGCAGGTAACTGGCTGCAGCCCGGCCCGTGACGCCCCTACCACAACCTGCCAACTG CTCCCCTACCTGGAGACAGGTGCCCCAAACTCCCACCGCCCTCCAGACAGTGTCCCCTCA AAATCAGTCCCCGATATTGGACAACTGGACAGTTGCACCAGAACCCAGGATGGATGTCCA ATACCCTGTCTCCAAGGACACCTGGATAGCTCAACAGATGCTCCCCAAAACAGAGCCTGC TGGCAGGATGCATACCCTCAGCTCAGCTCTCTCACCTGGGCACGTGTTCCCATCCCCAAC TTACCGTAATTTCTAACAGATGCTCCCTACCCAGTTCTTCTGAATATTTTAACACCTGGA CAAGTGACTGCGTCAACCGGCCTCCTGCATACCTGAACACCTGGTGCTGCAAAATCCAGC CCATCATAATCATTTCACATCTACACAAATGTCCCAGATTAGCCCACTGGAATATCTGGC CAAGCGCCCTCTACTTCACCCACTTAAATACCTGAAAACATGGACAGCTGCCCTAACCAA CACCTTAAACACATAAATATCTAGACAGATTGTTCCCTGACACACAAATAAGTGTTCCCC AACCCTTTCCAATCACACACCTTACAGAGGTGCTCCCAGTGCATCCCACTTGGATAGGTA AACACCTCAACAGGTATCCCCTCCACTTCAACATCTTCACCAGCCCCACTTTAATACCTG AGCACCTGAACAAAAGCCCCCAATCCAGACCCAGTAAGTATCTGGACAGCTGTCTCCAAC CAAGCCTACTTGAATGCCTAAATACCTAGACAGGTGACACTCACCTCATACCAGCCCCAC CTGAAGAGCTAAACACCTGGACAGGTGTCTTCCAACTCAACTTCACTTGAATATCTGAAC ACCTAGATGTGTGCTCCAATCCAGCCTCGTTTAAATACCTGAAACCTGGATATATGTCTC AGTTCTTCTCACCTAAATTACTAGACCGTGGCCCTGGTACCTAACCTTCCTGAAAACTTA GATATAAGTTCCTATCCGGCCCCACTGAAATACCTAAACAACGAGACAGATGCCTTTAAC TCAGTTCCTTCCTTGCTATGAAACAAATCCCATTCCCATCAGCTCCTGCCCCGTGACAGC TGTCCTTCCCTTCCCATCCTCTCTCTGCAACCCCAGCTCTATGAGATGTTCTCTTCGGTG ATGAAACACCTGCCAGGACCACAGCAACAGGCCTTTCAGTTGCTGCAAGGGCTGGAGGAC TTCATAGCCAAGAAGGTGGAGCACAACCAGCGCACGCTGGATCCCAATTCCCCACGGGAC TTCATTGACTCCTTTCTCATCCGCATGCAGGAGGTACACCCCAGCAGCCACTGCGGGGAG ATGCAAAGCCAGGCAGAGGGAAATCAGTCTGGGAGTGGGGCAGGCAGATGACACAGGCCC ATTCAAATTAACCCTCATCATAATAATCCTCACAATTGGCTGGGTGCCGTGGCTAACAGC CTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCGA GACCAGCCTGGCCAACATGGTCAAACCCCGTCTCTACTAAAAATCCAAAAATTAGTTGGG CATGGTGGCGCGAAGGGGGGCAGAGGTTGCAATGAGCCAAGATCACGGCATTGCACTCCA GTCTGGGTGACAGAATGAGGCCCTGTGTCAAAAAAAATTAATTAATTGTTTAAAAAGTAA GTGAGCCTGCATGGTCATGCGCATGTGCAGTTCCAGCTACTCAGGAGGCTGAGGCTGGAG GATTGCTTGAGCTCAGGAGTTGGAGTCCGGCCTGTGCAACTTAGCAAGACCAAGTCAGTA TAAGAAAAAAAAAAACAAAAAAAAACTGACAGCTAAGTTGATAATTGAAGGACAGATGGT CAGCAAGGTAAAGAAGGTGAGAAGGAAGAGCATTTTGGGCAAAGCCAGCAGCCAGGGCAA GGGCTGGAACCTAGAGCGAGTCTGGTAGATCTAGGGTCCCTCTTTCCACCTTTGGTCTGA ACCAAAGAGAGGTAGATCCAAAGGAAAAGCCCTAGAAGGGCCCTGAGGGCAAGAGGAGTG AGGTTGGCCTAAAGCCCCCTCTCCCTGCAGGAGGAGAAGAACCCCAACACGGAGTTCTAC TTGAAAAACCTGGTGATGACCACGTTGAACCTCTTCATTGGGGGCACCGAGACCGTCAGC ACCACCCTGCGCTATGGCTTCTTGCTGCTCATGAAGCACCCAGAGGTGGAGGGTAAGGCT GGAGGGGGACGGAAGTGGAGGGCCCCAGACCCTCAAAATTCCCCTTCGACTGGTGCAATG TCCCCACCTGTCCCAGATCCCGGGACCCTGAGACGTGACTTGCTGTCCAGAGACAGGGCA ACATTCAGCTGGTAGGCATCAGCTGAGTCTCATTAGATATTAAAATATTGAAAATGTCTG CACTGATTGGTCAGTCACTTCTGTCCCAAGCCCACTGAGTGCCCACTGCCCGTTCCACCG GGTCATCCCCTAAGTTCCTCCCTGTGCCTCCCCTGTGATTCTGGCACAACCTGGTTAACA GGATCCTACTCCAACAATGCGAATGGCTGATGTCTGTTCTGTTATGAATGCTCTACTTCC GTCTCATAGGCGGAGCCATATCATCCACCCCATTTTGCCTATTCGGACTATCATTTCCTG CTCTGAGACCCCTAGATACCTAAACACATTCCCCCTCCTCCCCCAGCCAAGGTCCATGAG GAGATTGACAGAGTGATCGGCAAGAACCGGCAGCCCAAGTTTGAGGACCGGGCCAAGATG CCCTACATGGAGGCAGTGATCCACGAGATCCAAAGATTTGGAGACGTGATCCCCATGAGT TTGGCCCGCAGAGTCAAAAAGGACACCAAGTTTCGGGATTTCTTCCTCCCTAAGGTGCTA TCCGCCCCCACCCCCCAGACTACGGGGACTTCCAGCCCCTCTCTGTGTCCCCAGCATCCC ACCCACATTAGAAGCTTTCTAGACCCTGTCCCACTCCCTCAATCAGTCAAAAAAGACTTC CCCAACCACCACATCCGTTCCACCTTTCCACTTAGACACTCCTGAGTCCTGCATCTCTCC AGACTCTTTGTGTCAGGAGAATCAAACACATGTTCCCAAACTTCCTATCTTAAGAAACAG AAGCCCCCTTTCCATTCGGCCTTTTGTCATAGGGACAGAAATCTCAGGTCCCCCAAACTC CTGCCTAGAAGGACATGGACCCCATGTCTCCCAAACTTCCTGTTTCAGAGATGTGAACCT TCTATCCCCCAAAGCTCCTCCATCAGAGGACCCCAACTCCTCCATGCCTGCCACTTCCCC TTACCTGGGGCACACTAGTTCCCCCTCCAGCCCCTGTGTACTTTCACCAATCCCCCGACC CTCCTCATCACACACAACTTCCTCCTCCCTACCAGGGCACCGAAGTGTTCCCTATGCTGG GCTCTGTGCTGAGAGACCCCAGTTTCTTCTCCAACCCCCAGGACTTCAATCCCCAGCACT TCCTGAATGAGAAGGGGCAGTTTAAGAAGAGTGATGCTTTTGTGCCCTTTTCCATCGGTA AGAGACCACTGTTTGCTGCCAGGCCACGGCTCACACCAGCAGGGGCCTCCCTCACCCTCC TCCCCTCTCTGCGGTGTAGCCTGGTATTTCTCCAGCTTGGAAGTTCCTGTTAGAATCTAC CCTTGAGCCAGCAGCTGATACTTCCTTAACTACCAAGCACCCAGTACCTGCGCCCAGGTA AAATGAAAGGAAACATCTTTCCCCGTAGATGTATTTCTCTAGGGTCACACAGCAGATTCC TCAGATCCCTAAAAAGGAGATGACGGCACAGCAGTCATATTTGCAAGTGTACCTGGCAGG AAAGGACATCTAAACCTCCCATTGCTACACCTGGCATGGATCACCCCATCTATGATGGAT GTGTGACATTATGCCTTTTTCAAAACCCATAGAACTGTATAACACAGAGTAAACCCTAAT GTAAACTATGGACTTTGTTAGTAATAATATATCAATATTGGTTCACCATTGTTACATCTC TTATAGAAAGAAATTGAGGCTCAGGGAGGATCAGAGCCTCCTCTGAAACTCTCTCAGGCC ATAATATTCCACCCTTCCTCCCTGGGAGAGCCGCAGCTGGAGGTCGGTACTGGGGCGAGG CTGCACTGAGAGTGGGCTTCACCTCCACCCCTCCCGCCTCTCCTCCTCAGGAAAGCGGAA CTGTTTCGGAGAAGGCCTGGCCAGAATGGAGCTCTTTCTCTTCTTCACCACCGTCATGCA GAACTTCCGCCTCAAGTCCTCCCAGTCACCTAAGGACATTGACGTGTCCCCCAAACACGT GGGCTTTGCCACGATCCCACGAAACTACACCATGAGCTTCCTGCCCCGCTGAGCGAGGGC TGTGCCGGTGCAGGTCTGGTGGGCGGGGCCAGGGAAAGGGCAGGGCCAAGACCGGGCTTG GGAGAGGGGCGCAGCTAAGACTGGGGGCAGGATGGCGGAAAGGAAGGGGCGTGGTGGCTA GAGGGAAGAGAAGAAACAGAAGCGGCTCAGTTCACCTTGATAAGGTGCTTCCGAGCTGGG ATGAGAGGAAGGAAACCCTTACATTATGCTATGAAGAGTAGTAATAATAGCAGCTCTTAT TTCCTGAGCA OMIM ID 122720