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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP2C8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1558
Official gene symbolCYP2C8
Full namecytochrome P450, family 2, subfamily C, polypeptide 8
Aliases,CPC8,MP-12/MP-20,
Gene summaryThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q23.33
Gene position96829254 - 96796529  Map Viewer
Gene orientationminus
Gene size32726 bp
Gene sequence
OMIM ID601129