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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP3A5 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1577 Official gene symbol CYP3A5 Full name cytochrome P450, family 3, subfamily A, polypeptide 5 Aliases ,CP35,DKFZp686L16231,P450PCN3,PCN3, Gene summary This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq] Location Chromosome: 7   Locus: 7q21.1 Gene position 99277621 - 99245813  Map Viewer Gene orientation minus Gene size 31809 bp Gene sequence >CYP3A5:complement(37278656..37310464):Length=31809 CTGCTGTGCAGGGCAGGGAAGCTCCAGGCAAACAGCCCAGCAAACAGCAGCACTCAGCTA AAAGGAAGACTCACAGAACACAGTTGAAGAAGGAAAGTGGCGATGGACCTCATCCCAAAT TTGGCGGTGGAAACCTGGCTTCTCCTGGCTGTCAGCCTGGTGCTCCTCTATCTGTGAGTA ACTGTCCAAACTCCTCTCTTTGTTTCCTTGGACTTGGGGTGCTAATCGGGCCCCTTTTCC CTTATCTGTTTTGAAGATCAAAAGAGATGTTCAAGGAGAAGTAGCTGAAGTGTTGGACGC TACAAACGCATAGAAGTTATTATTATCTTATGCAGATCTATGAATGAATAAATAAGCATT TCTCCCATCCACCTTCTAATTTTGGTGACTAGGAGGGTTTAGGGACAGCATTTGGTAGTG GGAATGATTTGATTAGCTTAGATCTGACGAAGACTAATCAATGAAAACATGGCAGCGGCA GATTACAAACTGCTGATCATGATGGACAGTGTGATCCTCATCCCCTTCCCAGGCTCTGGG GATTCTGGGTACAGGAAGGAGTGGCTTGCATTTTTGTCTCATTAATTCGCTTTCTGGGTT CTGTGTCTGCTGGAAGGGATGTGTAGCTGTATTGCCCCTGTAGACCTGGTTCCTGCTCCC CCGCCTTCCAACCCAGGATATCATTTACATAACGCACCAGGGGACACCAAGACTTCATGG GAAGCTGTCCCCTGGCTCTTCCCTCTTTCCTGTGCCATGCCCCTGAAAATCCCCTCCCTC CTATGAGTCACTCCTCCACCCTGTCATACACAGGATGGTTTATCTTGCAATGATTAACCT CTAGAGCAAAGGAGACCTGGAGGAAGTTTCGAGGATTTATTCTTTGCTTTAATCTTTTTC CTCCCGTCTCTGGGAGGCTAGGATTAATATAGAGCTTTGTTTCTCACCTAATGGGAATCT ACTAGCAGCCTGAAAAGGCAGGAGCCATGAAAGCCAATTTGGATTTTACATATTTTTCCC CTTTATGTTACAGTACAGGAGGGCAAACCCTCTCACTGGTGGGATTCCTGGCATCCTAGA GCAGGTGGAGAGAAGAGTTACTTTCCACTGTGGGTAGTGGAGGCTCCACCTGTCCCATTA ACTTCTACCTCAATTTGACTTTTATTAAGAGCAGGGAACCACAATGACATGAAAATAGAC ACTATAAACCTCATTTTAATTCTTTCACAGAAAGCTTAGGAATTCAGTGAGTTGTGGCAA CATGGTTTCCATTGTCTAACATTTTTAAATGAATTGATATGGTTTAAATTCATTCATTTT TAAACCAGAATTTTTTGGAGATAGACTATTTCCAGCATGTTCCTTCTGGATGGTAAAACA GGGCTGTTAGTTCAGTATTTGTGACAATAAGTGTGTGTAAAATAATGTCACCTTTCCTGA ATGTCAGGAATATGAGTCTAATGCACAAATGTATACCTCTAAGACAAGACTGCACGTCTT TTCAAATATACCTGTCCGGCCATTTATTTTAATAACTCCTTTTCGAATATACCTGCTTAG CAGATTGTCTTAAACTCTCAGGACAGGGGAGTAAGCAAGACTGTGAGCCAGTGACGATAG CAAAGGCTTCCAGGTAGGATCCATATGAAGTGAGAAAATATTCCTCAGCTCTCAGGGTAG AACTCCAAAGAGATATTCATGGGTCCTGGCCCCACCGTGGAGGTCACTCAAAGGGCAAAC AGGTTGGCATCTCATCTGCTTCAAGCCTGGACACAGGGGCACCATCTGTGTCACTCTGTG TGTGGTCTGCCATGTTGTGGGCCGGTCACTACAGACTCGGGCAGCCAGGCAGACAATGCC TTAGCCTTAGACAATGCTGGTGCAGCCCAGGAGTCAGAAAATGCAGTGTAGACCAGGCCC TCCTTAGGCCAACACAATTACATGCAATAGATGACTGGCTTTTCTGTTAGTCTCTTCACT GGACCCAAAGGCTGCATTACTCTACCAGAGGGGAGCTGGAAAGAAACTAAAGAGTTCGCC CAGCACAGCATCTGCCTTGACATGGTACCATGTGAATCTAGACACTCACCAAGATCTTTC CTTGGGGGCCAATGCTGCTGACACATTAACTCAATAGCTTGTCCTCACCTGAGAGGTCAG GTAATGTGTTTAAAGTTCAGGAGCAGAGATTAGTGTCATTGATTTGACATGGCTGTGACA ACAAAGGAGGGAACTGAAGTGGGAATACCCAAGGCCACCCTGGCTTTGGCAGGTGGTGCA CGCACTTCCACTAACTGTTCTGGGGCAGGGAACCAAATGTATGACTGGGCCTGCTCATGC TGCCCCTGCTGAGTCCTCCAAACCCTGCCCTTCATGTAATTTCTCAGTTTTATTTTATCA CATTTTATAAGTCACTGGATGTTTACAAAATGTTTGGAACCTATACTGCCTTGAAGGCTA ACCTCTAAAGAGGAGTAAACAAGGTCTTAATACAACTCTCCGGGACGTTTTATCATTACT TATCTTATATGCCATACTGCACCATTTGCTATCAACAGGAAAGTACCTGGACTTTGGAAG GTCCCTCTGTGTCTTTTAGCTGAAAGTACATATGAGGCATGTGGATTCTTTTATGCACAT CATCTTTTTCAGCCACATTTTTGTAGTTTGCCTCTCTGGAGCCAACTGTGTGGGGCTAGC AGCTTCACAGCTGAATCAGTGTCTGGCAACCTCTTCCTTCAGCCTCTCTTCTTCCTCCAG TTTTCCATCCCTCAGTCACACCGGAGGGGGAAGGTCTGCAAGGATCCAGAACCATCAGTT GGAGGAGTTTGCACATGACTCATGAAAGATGAGTTCCAGGCAGGCCTGCCATAGTGAACA CCAGGCTTAATGGGTTTTTCCTCAGAGATACTTCACGTACAGAGGCAGTGAACTGACTGC TTTCTGGTTGACCACCTTGAAAAAGATGAGTGTGCCTGGCACTGTGCTTCTCAGGTGAGT ATGACCTGAGAAGTATTAGTTGCTGGTTCTTCTGCACACAATCATTCAAGGACATATGGA TCAACCATCCTCCTCAACAGCTCAAATCAACCAGATCATCTGACCACAGAGACTGAGGTG TACCTGAAAGCTGCCCACATTTCTATAAGGCCAATAGAAGCCATGAACACAGTTGTCAAT CTGTAGAAATAAGGACTCCATGACTCCTCCAAGGCCTCTCTGTGAATGAACGTTTAAGAA GGGCTAGATCCTAAAACAGGGTCAGAGCTTAGAGGGAAGAAAAAGCATAAACATTTCTGA GCAAATTGTAAGGGCAGTGTCACCATAGGCTCCCAGTGACCCTCTGTGATTGAGTGCATA CAGTGATGCAAAATCTCATCATCAGTGCAAAAGACAAAAAAAATCTTACTCTTTCTACCT AGGATGAGAGTCCCCAAATCAGCGAAGAGTCCACTTACTAAACAGACATAAGGAAATGAA GTGTCCTGGAAGAATTCCTGCCTGAACCTCTCAGGAGCATTTGAGGACATTTATCAAGTA TTCACTCCAGGATTGGGACTATGAAGACTTCAGCTGCTTTCAGCTAATCATTGAGACTTT TCAGGGGTCTCAGAATAGTCAGGAAAGGACCTGATGAGTGAATGCAATTACTGATGTTGG AGTTGCTGTTATTATTTATCGTGTACATATTACCTCCCTCTCTTGACCATTCCAGTTCCT GAGTAACTCACCAGCCCTCTGATCTATAAAGTCACAATCCCTGTGACCTGATTTCTGTTT CACTTTGTAGATATGGGACCCGTACACATGGACTTTTTAAGAGACTGGGAATTCCAGGGC CCACACCTCTGCCTTTGTTGGGAAATGTTTTGTCCTATCGTCAGGTGAGTTGCTTGAGCT TCCTCTTTTGCTTCTTATGGTTGCAAACATCAGCTTAGTTCCATCAGTAAAAATGCCCCT CCTTGGGAGGGAGTTCTGAGGTTTCACATTTTCAGAAATGGTGGGACTGGGTGCAGTGGA TCATGCCTGTAATCTCAGCCTCTGTGAGGCCAAGACTGGCAAATTGCTTGAGCCCAGGAG TTTGAGAACAGCCTGGGCAACACAGTGAGACACCTGTCTCTAGAAAGAAAAAATTACCTG TGCATGATATGGTAGCCCATGCCTGTAGTCCCAGCTACTCTGAATGTTAAGGTGGGAGGA TTGTATGAACCCAGGAAGTCAAGGCTGTATTGAGCTGTGATCGCACCACTGCACTCCAGC TTGGTCAACAGAACAAGACAGAAAGGAAGAAAGAAAGAGAGAGAGAGAAAGAAAGAGAGA GGAAGGAGAGGGGAGGGGAGGGGAGGGGAGGGGGGAGGAGAGGAGAGGAGAGAAAAGGAG AGGAGAGAGGAGAGGAGAGGAAAAGGTGTGTAGGCTCCACCCAAAGCATGGCCAGGTTTA CCCCTGGAGGGAAAGTCACAAGCTCATGTCCAGAAGGCCAGTAGCAGCAAGCTGCTCTCC AGCCCAGATTTCCTATCCTGTGTACCTGGAGCTTGTTTCTCAGATTCTAACTCTCACAAC TGAAGCCTCTGTTGTCTGATTACTATCTGAGAATTCTACACAATTTTACCCTCGATAAAA GCAGTAATTTCTTCTTCATCTTTCCCAGATCAACTCTTGTAGTAGATCAACATTTCTGGG ACCTTCTTTTGCATGGTTAAAACATCACAGCTGAATCTTAGCAACAGGAAGGTTTGTTTT TATGTTTCAGAAGTGAAAGCTCAGAGCACGCATTGTAATTTGCTGGGTGTGATGTGTAGA GGTGGCATTTCTCCATCTTTTCTGTGTTAAGCTAGAAAACTGGAAAGGAAGTCTACTTTC TCATTCACTCACTCACTTTCTCACTCAACAACATGCCTTAGACTTATCTAAATCTGCAAG ACTAAAAGAGGTTCCTGGTTTCTTTAACTTTCTAATTCTGCTAGAGTTCTAGAGAGAGCA CATGAGATAAATGAAAAGGATACTGATGGAGGAGATTAAAAAATTGTGCATTCCCTGCAG ACACTCACTTTTCCTCACCTCAGTTTCACCCCTGCCCTTGCAGGTGATCATTCACGGGGT TAGGAGACTTTAGAGAGAATAAAAGAAAAAGCAAAAATACATCAGAAAGACAAGGAATTA CTTACTGGTCATAGACAAGGGTGAGTCCTTCAGTACTTAGAGAAAATTCAAGAGTGACTT TAAATTCCCCACTTCAAATATATTCTCTGTTTTCTTGTCTTTCCCTTAAGACATCTCTGA ATAGCTTCCTTCAACTGCCAGTGAAAGATAGCAGGCCTGATTTCATTGGACGCAACTGTT TTCAGCCCCAATTAGAGGTAGGGTTTATTCTATTTAAAATAATAATCAACTTGTATTTTG TTTCCTCTCCCAGGGTCTCTGGAAATTTGACACAGAGTGCTATAAAAAGTATGGAAAAAT GTGGGGGTGAGTATTCTGAAAACCTCCATTGGATAGACCTGCTACTGTGAGGAGGTTACC CCACTGCAGGATAGTCTCTGCCCAGGTCTTCATGGGATGAAGCTCTTGTCAACCTAAATA CAAACAGAGAGAGGTTCTCTGAAAGAAGAGGATAATTACTTGGGAGTAGAATATTGCAAT GGGAATCTGCTTGCCGTTATAAACTATGTGCAAATTCAGGGAGGTAAACAAGACAAAGAT GCTCCATAGAAAATATGAGAAGAATCTCATAACTGTTTTGAGATAATTATTGTTAGCTAC AAAGATCAATAACAAGGGTGATGCCACACCAAGGTTGGACAGGCAGTTGCTGGACAGGTG TCCTTGCAGAAATATTTTTGTGTAAAGTTGAAATAGCCTTTGTGCAAAGTTGTGGTTTTT GTAGACACTTTTGTAATAGTTTTGTTTCCAGGAACACAAGCATAAGAATCCTCTCTTCAT AGCCTTCTTGGGATTTATTTGTCAGGGTTAAAAAACAATTAGTGACATCACTTTGGTTCT GATAAAGTTCACACTCGCTATTGTAAAACTTTTCGAGGCTTGTCCTACCAAGGATCCCAT GTGTCACCAGGTATCGAGGTCTTCAGTCTGAACTAGGCTAGGAGCATTGTGGTTACCACT TTTCTGCAGGTTTTGGTGGCCCAGGGACTCCCAGCATCGCCTTCTGTCCAGTGTCTGCCT ATTCCCCTCTTCTTTTTTTCTTCCTTAGGTGCCCTTTTATCACATGCATTGTCTCAGACC CTTCTAATATGTGCTCATAAATGCATGGCATCATCTCCTTCCCACATTGATTCACTTTCA ATTAAAAGCCAAAACTCCTTCATTTAGACTGAATTTAACATGTGCTTTTGAAAGAAGGGT TGAGAGATAATAGAGAAACAGATTGGGAAACCACTTATGCTCCACTTTTTTAAACTTTCT CTGCAAGTATGGAATTTTTTGTTCTGCTTTGTTGTTTAAATTTAAGCCAAAACTTCTTAA TAGAAGGATATACAAATATTTATTGGTTTATACCATTGCACTTACTTTGAAGAAGAGATG CTGAATATTATTAAACCATTGTGTTCCCTGGTGGGCTGATGGACTGTGATTTTATAAGGT GGTCTCAGCCAATTGCAGCAGCTGTTCCCTGTCAGAGGGGCTAGAGGTTTGGTGAGAGCA GTGGATGAGGTGCAGTGGTGTGTTTGTTCACTAGAAGCAAGTGGGAGAAAGCTTTGCCTC TTTGTACTTCTTCATCTTCTCCCCTCAAGTCCTCAGAATCCACAGCGCTGACTGTGGAGT GCTGTGGAGCTGGCATGGCCCATACAGGCAACATGACTTAGTAGACAGATGACACAGCTC TAGATGTCCATGGGCCCCACACCAACTGCCCTTGCAGCATTTAGTCCTTGTGAGCACTTG ATGATTTACCTGCCTTCAATTTTTCACTGACCTAATATTCTTTTTGATAATGAAGTATTT TAAACATATAAAACATTATGGAGAGTGGCATAGGAGATACCCACGTATGTACCACCCAGC TTAACGAATGCTCTACTGTCATTTCTAACCATAATCTCTTTAAAGAGCTCTTTTGTCTTT CAGTATCTCTTCCCTGTTTGGACCACATTACCCTTCATCATATGAAGCCTTGGGTGGCTC CTGTGTGAGACTCTTGCTGTGTGTCACACCCTAATGAACTAGAACCTAAGGTTGCTGTGT GTCGTACAACTAGGGGTATGGATTACATAACATAATGATCAAAGTCTGGCTTCCTGGGTG TGGCTCCAGCTGCAGAATCGGGCTAGTGAAGTTTAATCAGCTCCGTTGTCCCCACACAGA ACGTATGAAGGTCAACTCCCTGTGCTGGCCATCACAGATCCCGACGTGATCAGAACAGTG CTAGTGAAAGAATGTTATTCTGTCTTCACAAATCGAAGGGTAAGCATCCATTTTTTGAAA TTTAAATAATGATTGATCCACTGATTAAATTTTTATTTTGAAAAAAACATATATTCACAG AAGGTTACCTAAAAAATGTACAGGAAGGTTCCATGTACTCTTCATCCTGTCCCGCCCAGT GGTAACATCTTGCAATCTTGTATATTGCAATATATATCTAGTATATTCATATTATCAGGT TGGCACAAAAGTTAAAATGGCAAACTACAGGCTGGGCATAATGGCTCATGCCTGTAATCC CAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGTTCGAGATCAGCCTGA CCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGCGTGTGGTGGCAT GCGCCTGTAGTCCCAGCTACTCAGTAGTCTGAGACAGGAGAATCGCTTGAACCTGGGAGG CGGAGGTTGCAGTGAGCCGAGATCACGCCATTATACTCCAGTCTGGGCAACCCAATGAGA CTCCATCTCAAACAACAACAACAACAACAACAACAAAAACCGGCAAACTGCAATAACTTT TGCACCAACCTAATACTATAGTACAGGAAATTGACTTTGATATAGTTTACAGAGCTTTTC AGATTTCACCAGTTTTACATGCCCTTGTTTGTGTGTGTTTATGTGTGTGGGTAGTTCTAA GCAATTTTTCACATTCGTAGATTTGTGCAACGACCAGCACCATCAAGATGCAGACCCATT CCGTCACCATGTGGCTCCCTCCTGCTGTCCTACAGTCACAACATGGAGTTTGTCTTTTTC TCTGACAGGTTCTATATCAGAGCAAACTTTTATTTATTTGAGGAGGCCAATGTATTAATA TTTCCTTTTATGGATTGTTCTTTTGGTGTTAAGTCTGAAAATCCTTTGCTTAGCCCTCCT TCCTACATTGCTTTTTCTAAGAGTTATATAGTTTAACACTTTACAAAATGTAACTCTATT ACCCATTTTGTGTTAATATTTGCATAAGTTATGAGATTTAGATCAAGGTTCATTTTCTGT GGACTATGGCTGTCCAAATGTTCCAACACCATTTTGGAAAGGTAGGCATATTGTCAAAAC TCAGCTGAGTATATTTTGTGAATCTATTTCTTATTGTTTACTCCTCCACTAATACCACAC TGTGGTGACTCTAGTAGCTGTACAGTAACTCTTAACATCATATAGGGCAATTCTTTCCAC TTTATTGATTTATATTTTCAGAATGGCTTTAGCTTTTCTTGTCCCTTGCCTTTCCATAAA AATTCAGAATAAGCTTGTAAGTGTCTACAAACAAACCTGCCATAATTTTGATAAGAATTA AAGCAGAGGTGTCCAATCTTTTGGCTTCCCTGGGCCACAGTGGAAGAAGAAGTGTCGTGG GCCACACATAAAATACACACACACACACACACACACACACACACACACACACACACACAC AAATGGTCTGTGTATAGTTTTCATTATATATCTACCACCACAGATAAGCAAAAATGTCCT TGCATAATAATCCTAATTATGCACTGCCCCATTCAGAGGGTCTTTCAAAATCATTGAACA GGTTCCAAGTTTGCAATCACTGATACAGAAAATGTACATATCTAGCTAAACTTCACTACT TTTTTGATATTTTTTATTATAAAAGAAAAGAGAACAACATAAAACTAGTGGGGTACTTGA CATTGTTTTTGAGAAACTAATCCATCAGTATCTGGCTTGATGGAAGTAGTTGCAATTCTC AGTGAGTTCTCAAGGTGCTCATCAGATATTTTGGTTCTAATTTTACTCTTCGTGTTCTTC ATCCTTGAAAATAGTAGCTCACAAATGTAAGTGCTGCCAAAAAGCAATGACATGAACAAG GTGTGATTGTGAAGCAAGGGATATTTGTCATTGGGAAGACAGGTCTTACAAAAGTCCAGT AAAGAGGCAAAATCAAATTTTTCTATAAGTTGAACATCAGATTGCAGCTCTAGGCATTCC ATTTCAAAATTGCCAGGTAACATATATATGTCGACTGAAAATGGAGTTGCAAATATACCA AAATATTGATGATTTTTTCAGAAATCTTGAAATACCTGTTTTCAAATTCCTGTATCAAAT TGAAAAGCAAGGCTGCGTATTTTTGGCTGTTCACAGGACCATGTTTAGCCAACATGTCGA AATGCATAAAATTGTTTGCCTTAATTTGAGCTTGCCATAATTTCAGTTTCATATGGAATG CTGTTATGGTTTGAAACATTGTATTGTTAAGTTGGTTTTCAACTTGAAGACACAGGTTTA ACTCACTTAAATGGGCCGTCAAACCCACTAAAAATGCTAAATCTGTAAGCCAGTTTTCAT TGTCAAGTTCTGGCACCAATTTTGTTTGATACCATAAACAGCTTGATTTCACATCACAAA GCATAAAATCTTTACATTTTGCCTTGACTTAACCATCTTACTTCTAAAAAGTGAATGACT TGCTAGAGTCAGCATCCATACTTTTAAGGAATTCCTGAAACTAGCGATGATTCAATTCCT GGGCCCTTGTGAAATTTACAGCCTTGATGACAATTTGCATGACGTTATCTACTTTTAAAG CTTGTGCACATGGATTTTCTTGATGTATTATGCAATAATACTTCATCAAATGTGAGTTTT GTGTGGCAACTGCATCATCTATTAATTGTACAAGTCCCTCTCTTTTACCTACCATCGCCA GGGCAGCATCTGTAGCTATATCACATATGTTTACAAAGGACAAAGAAAATTGCTTTAACA TATTTTTCACTGCTTCATATAAATCTCTTGATTTAGTTGTGTCTTTTAATAGCATGGTGA CATTTCGATTTCTTCAGTGACATTATATTCATCATCAATACCTCTAATAAAAATAGCAAG TTGTGCCGTATCTGTAGTGTCAGTGCCTTCATCCATCACCAAAGCATAAAATTTTAAATT AGCAGTTTTACTCTCCAAACGTCTTTCAATAGATTTCCCAATTTCTCCAATTCTCCTGGC TATAGTCTGGTGAGACAAACTGATTTTAGAAATATCAGTTTCTCAAGGCAAATAATATCT ACCACATCTTCCAGACATTGCTTAATAAACTCACCATCAGTAAATGGTTTTGATTTTTTT GCTATTAAATTTGCTACCACATAACTAGGTTTTACCTTACGATTGAGTCCGAGTTGTAAC TTTTTAAAAAATCTTTTTTGTTGAAAAGACAGACTTTTTTTCAGTTCTGCTATTTTGTCC TTACAACACATACACACCAAATTTGTCAGCACGTTTTTGCATATAATGCCTCTTCAAATT GTAGTCTTTGAAAACTGGCACAAATTCCGTGGAAATTAAGCAGAGTGCTTCGCTATTTGC CTCAACAAGAAAAAGTCATTTGTCCACTTTTCATTGAACAATCTTCCTTCATCCATAATT TTTGTTTTTTAGGGTTTTCTTTTTAAGACATTGTGGAAGCCATTCTGGAATTAAAAGCAT TATAATAGATAAGCAACTATATTTACTTTTATTATGGAAATTAACAGATAGGAAAATAGA ACAGAAAGCAAGGTTTAATAATCAAATAAGAATACTTACATGTCTTCTAAATAATATTAA ACACCTATCATCTACAAAGGTAGGTTGAAATATTATTGATAATTGCTGGGTTTTACTTGC CAAATTGCCACAAACACACCTAATACCTGACAGTGTCAATTCAACTGTCCGTGATTAGAA GATAACACACTGGAAGTCGCACACCACCATAAAACTGAAGCCACACATGCGTACAAATGG CGACAGTGTCTGGTGTACAGCAGCGCTCTGCCTTGTCCAGAATACACACTTGAATTCTTT GTCACAATTCACTTCACGTGGCACTGCAATAGCGTCCTCTCGCTCTTTGTTAGTTAATTT TAATGGCTTTTAATTTCTTCTTGCTGAACTGTTTGCAATTATAATGCAAATTATGGATAC TAGTCCATTATTTGTGGATGTGACATACTCTGATTACCCCTTTCCATTCCATTGTTGTCT ACGAAGTTCACACTTGAGAATCACATAGTCAAATTACAAAATTACAAAAAAAATTGCAAA AAAACTCAAAATGTTTTAAGAAAGTTTCCACATTTGTATTGGGATACATTCAAAGCCATC CTGGACTGCATGAGGCCTGCAGGCCACAAGTTGGACAAGCTTGAATTAAACCAATAGAAC AATTTGGGTATAATCTATATCTTTACTATGTTCAGCCTTTCATCCCGTGAATATAGTATG CCTCTCCATTTCTTTAGCTTTTATTACTTTCCTCAACATTTTATAGTTTTCAGCATAGAG GTCCTGTACATCTTTTGTTAGATTTACACCAGAAATATTTCATTTTTGTTGGAGTAACTG TAAATGATACTGTTTTTCTTGTATTTTCAGATATTGATTATTGTTACATAGAAATGTGAA TAATTTTGTTTGTTGATCTTGTATCCTATAGCCTTGCAGAACTTACCTATTCGTTCTAGA AATTTTTTTGTATATTCCTTGACATTTTATACATTGACAATTATGTCACCTGAAAATAGA GACAATTCTATTATTTCCTTTCCAATCTGTATGCCTTTTATTTCTTTTTCTTGTCTAGTG TATTAAGACATCAGGTATGCTCTTTAGTAAGAATGTTGAGAGTGGGCATTTTTTAGTTCT TCTTGATCTTGGAAAAACCATTCAGTCCTTCATCATTAAATGTGATTTAACTGAATGATT TTTTTACAGATTGTCTTTATCAAATGAAGGAACTGTCTCTCTCTTCCTAGTTTATTGAGA TTTTATCATGACAGCTGGAAGTACACATTTTAAAACAAAACATAGTTGTGGAAGATAAGA GAAAGTTCCAAGCATGCTGGCTTGATAGTCCAGCCCCAAGTTGGGAAAAGTAATTATCCC TTTCTTTTTCCTTCTATTTATGGAATAAAAAATTAAGAGAAAAGAATTTTCAAGGAAATT GCATTATTCCTTCAAAACAGGTTTCTAGTCTTTAAGTATTACCTACTTTTCAAAAAAAAA TCACCACATCATGGCATCCCTTTTTCAAGTTGCCCATGCTGTAGGTGTATTAAAGACAGA GCTGGTCTGAGGCAACATACAGTCTGCCCATCTGTCACCAATCCTTTTCTACTCTGCACA CTCCTGGGGAAGGGCTAGGTCTTGTTCCTGTCTATTCCACTGGAAGAACAGTTCCCTACC ACGTGGAGCATTTGCAATTAAAAGGAGACTGAGATATAGAGGCAGGAGACCACACCAGAT GGCTGGGTCTCCCCACTCCCACCCCCGCCCCACATACACTCAGAAGAGGCTAGGCATCTA GGATCTCCATTGAGCATCTTGAATATGGCTTGCCATAATATCATATACAGTCAATAAATA TTTGTTAAATAAGGATGCCTCTTCAATATATTTTGTGCAACCATGAAGATCACCACAACT AATGTGAGAAAAAATGTTTCTGTTGAACTCTAGTCTTTAGGCCCAGTGGGATTTATGAAA AGTGCCATCTCTTTAGCTGAGGATGAAGAATGGAAGAGAATACGGTCATTGCTGTCTCCA ACCTTCACCAGCGGAAAACTCAAGGAGGTATGAAAATAAGATGAGTCTTAATTAGAAATG TAAAGAATGAATCTGGGGACAGGTAGAAAGTAAGATCACAGTCCGTTTCCAAGGGGTAGT CCACTGAGTTCGAGCTTCCTAAAAATGGTCTTTTATCTTTATGTACAGAAAAGACATCAC AAAATTCATTACAAAATGTCACTTACTGCTCCATGCTGGAGAAAGCCATATCCTTCTGGG ACTTGAGTCTGCACATTTAACTACAGGTACTGATCTGTTTTGTGCTTAGATGTTCCCCAT CATTGCCCAGTATGGAGATGTATTGGTGAGAAACTTGAGGCGGGAAGCAGAGAAAGGCAA GCCTGTCACCTTGAAAGAGTAAGTAGGAGCACAGCCATGGGGTTCTGAGCTGTCATGAGC CCTTCCAGCTGCCTGCCATGGAGTCGACAGTCGCACTGTTGGGTTACTCCAGTGACCAGA CAAAAGCAGGGCAGCGCTGCAACTCCAAAGAGCCACCTAAGAGGGAGTGGCTCCCATGAG GCGGCAAGTCAGCAAGGGAAAAGGGCCTTCTCTCCTGTGCACAGGAGCCAGGATTTACTT ATCTGTTAACTTGTCACCATAAATATTCTGGGAGATTAAATACATACTTTAGAAATTAAA AAAACATGATTGTATCAAAGTTTTGAGTGTAGTGGATATGGAACTGTGGGTAAGCAAGCA TTTGGTACTTGTTGCCTTGCATTGGGTAAGATGGGAAAGTTACAATGGGGAACTTGGAAC AATTTCAATCCCTTCATGGTTTTTCTGAGAATATCAGCAAACTATGAACTATTAAACCTT CCCACTACTTCCTTTTCCTCCAATCTCAAAAAAGAAAGGGTGCTAGAAATGCTATGTGTA GAGCAAGCCTATTATTTGCTGTCTACAATGGTATGTGCTTCAATTATGCAGGAACGACAG GTGTAATCTGAGCCTGTCCTGTTCAGACTTGGGACATGTGGTCACTCAGTTTTGGGTTCT CCAAATCAATGTTGGAGAGATCTATTTTTTTTAACCAGAACATTCTTGATTGTCACATCT TACAAAAATGACTCTGCTCTCAGCGCAACTTCAGGTCAGAGGAGCTGGGGATAGTGGGGT TTTCCAGAGCATTAGCAGGGAGTGTAGAGAATAAAGGATGATATTTCTAGGAACTCAGAA CAGGGTGTTACTGTTTTGTAAAGTGTTGAAGAGGAATTGGCTCTGGGCATAGAGTCTGTA GTCAGACAACGCCACCTTTCTTGAATCCACTAGGAAGAGTTAATTATTCTACTCTTGTTC TGCTGAAGCACAGAGCTTACATATCTTATATCATCCACACTCAACACATGCTACTGTAGT TGTCTGATAATGGGTCTCTGTCTTCCTATGACTGGGCTCCTTGACCTCAGAGGTGAGTCT AACTCAGCTTGGTGTCTCCATCACCCCCAGCATAGGGCCAGCTCCATCACTGGCACCAGA TAACCACCTTCTGAGGGAGTAGATGGAAGATGATTCAGCAGATAGTTCTGAAAGTCTGTG GCTCTTTATGTGTCTTGACTGGATATGTGGGTTTCTTGCTGCATGTATAGTGGAAGGACG GTAAGAGGTGCTGATTTTAATTTTCCATATCTTTCTCCACTCAGCATCTTTGGGGCCTAC AGCATGGATGTGATTACTGGCACATCATTTGGAGTGAACATCGACTCTCTCAACAATCCA CAAGACCCCTTTGTGGAGAGCACTAAGAAGTTCCTAAAATTTGGTTTCTTAGATCCATTA TTTCTCTCAATAAGTATGTGGGCTATTATTTCTTTCTCTCTTTTTAAAAATAACTGCTTT CTTGACATATAATTCACATATCGTATAATTCATCCACTTAAAAGGTACAATTCCATTGTT TTTAAGATAATCAAAAATATGTATGACCATTACTATTGTAAACTAAAATGTTTTTGTCAA TCTAGAGCCCTCACACACTTTAGCTGTCAACACCCCACCACAAACCCCACTGCCCTAAGC ATCCAATAATCAACTTTCTGCCTCTATAGATTTGCCTATTCTGGACACTTCATAGAAATA ATATCATTGATTTTTCTCTGTTGTTTTTTATTCTCTATTTCATGAGTTTATTTTAGTCTG TTATTTTCTTTCTTTTGCTGGCTTTAGGTTTCATTTGCTCTTCTTCTTTTAGTGTTTTGT GGTGTAAATAATTATAATCAATTTGAGATATTTTCTTCTTTTAAATTTAGATATTACAGC TATAAATTTCCCTCTGAGCACTGGTTTGGCTACATCCTGTGTTTTGGTACATCATGCCTT CTTTTTGTTCATCTCAAAACAATTTCTTGTTGCCCTTTTGATTTCTGCTTTGACTCACTG GTCACTTAAAACTGTATTGTTTAACTTCCACAAATGTATGAGTTTCCCAAATTTCTTTCC CTTATTGATTTCTAGTTTTATTCCATGGAAGTTGATGTACATATGCTGTGTTAATTCTAT CTTGACTATCATTTCCTGAACAGCATGATTAAGTTAAGCAGCAGATTATGGTCTACATTA ATCCAAAAACTCTAGTCCAATAGATAAAGGCTAAGAGGTCAGGGAATTTAATTCTATTAC TTTGGTCACTCCAAAGACTCAGAAGGTGCCATTGATCTCACTGCTGTAGTGGTGTTTCCT ATGTATAGACCTGCCCTTGCTCAGTCGCCGGCCTGAAAGAAGGGCAAACATGATAAAAGG AATGGGTTCCAGTTGAGAATCATGATGTTCTTATTCTTATTACTGGTAGAGAAAATTATA ATTGCTCCAGGTAAAGTTTGCATTTTCAATGATTTCCTTTTGTTTGTTTTGTTTTTCCCA CAGTACTCTTTCCATTCCTTACCCCAGTTTTTGAAGCATTAAATGTCTCTCTGTTTCCAA AAGATACCATAAATTTTTTAAGTAAATCTGTAAACAGAATGAAGAAAAGTCGCCTCAACG ACAAACAAAAGGTAAAATCTGATGGTGGTTAAATGACGATGTTTAGGTTTTGATAAATTT AGATTTTATACACATGATAGAGCATGTATCTGTATTTTTAAAAATAAAGACAGAGAACTT ATGTTTAGAACAAGAGAAGCCATTTGGTAGAAATAAAGAAGGAGATTGGGGAAGGAGATG AGAATGAGTCAGAGAGATAGCATTTAAAACTTGAAATCAGGCACAACAATTAGTATGTCA TGATATAAACAGTATTGAGATAAAATTTTACCACTTCTCTTCCCTTTAATAAATTGTCAA AGGATAAAGTTTCCTGTTTGAAAATATATTTTACTGGTATTGTGCTTTCCTCATATCACA GATTGGTAAAGAATCATTTTAAGTCCAAGACTCTTATTTTACATATTCTGCAATTAAAGG TCCTATGAGGCTACCTGCCGACTGCTGACATGTAGTGTGTGGTAAATGTGAGTGTTTCAC AGCCTGGAGTGAACAGGGGTCTTCTCTGAGAATTGAGGTTGCAAGGCTGGCTAACTCAGC TTTGCCTTCACGAGCCCTAGAGGCCAGCCGAAGGATGTCTGCAGGTCAGGGAGACAGGAC CAGGTAACCCAGCTGTCACTGAAGATTATATAGAGTTTGAGAATGTTGGAATATTTGAAA ATGCTCCCCCAAAAAAGCTGCTGATGAGTTCTGGAAATGTCAGGAGATTAATCTATACGG ACACTGCTGAAGAAAAAGGTAGAAGAATAAAAGATCCAGTACTTCTTCCTGGGTAAGCAG TTATGACCAGAGATGGAACCGGCAACTCTTTGGCCAGAAAGCTGTATCCAAAAGACAGAG AAGATGAGAAACAGGGAGGGCAAAGGCGAAAAAGCAATTGGACATGATAGCTAGATTTGT TTCAGGAAAACATCCTGCTTTCCAAGGATTTAGATGAATGTTTTTGTTCACTGGTGACTC AGGTAACACGTCTTCAAGAAGCCATAGGGAGGTTGAGGGAGGGAAGTCAAGAAGGGAGGT TGAGGACTGCACTTTTGATTTACTTCTGACTTCACGAGTCACTTTCTGCCAAAGAAATCT CTCCTTTTGCTTCTAGCACCGACTAGATTTCCTTCAGCTGATGATTGACTCCCAGAATTC GAAAGAAACTGAGTCCCACAAAGGTAACCAAGGAGTGCTTCTGAGGGCTACTGGCGGGGA CACTAAGAGGGAGGGCCTTGTTCTGAAAATGTGCAGGAAGTATTCCAGGAAGATGAGAAT TTTTGCCACATAGCAGAACAACACACATTTAGATGTTATAAATGGTAGCTGGAGGCACTT TCCAGAAGCCCACAGGTATAGCCATGTTCCAGGCTGAAAGGGCAACCCTAAGCAAACCTA GAATGCTTGGAGGACAGTCAGTGGTTTGTGGATCACCTACATGAGATCAAATGCCAGTTC TCAGCCTCCTCCAGATCCACCAAGTGAGAACCTCTACTTGGAAATTTATATCAAACATAC CGATCAGGAAGCACACTATCCCAGTAAGGGTGATTTTAACTGGCAGTACTTGAAAGTGTG TTCGCAAGGTTAATCTACTGCAAAGTTTTATTTTTCCCTTTGAAATGCATAAGTAACTAA TGGGGGACACCTCTGATACCATGTAAATCTACTTCAATCTTCAGTCTTGTATCTACTAGT TTTATGACCCATGGATGGTTTTAACCAAAACCATTATTACTAAGACAGTGGCAAAATGAT AACCATGGTCAATTTCAAGCTACCAAGATTTGGCAACCATCTCACAAAATTTTTGAATAT TTAACAATTGGTTCTAGAGAGCAGGACTCAGCAGACTCCAGTATACCACTTTAAACATGT CCATGTCTACATCTACTTCTGTCTGTCTATCTATCTGTCAATCATCTATCTGCCTATAAT TTATCAATTAATCATCTATCTATCTCAACAAAACTTGCTGTGATAAAGAAAATAGTCTAT CATTTCACTGTTTCATATAGAAATCACTAGACACATATGGCTATTGAGTACTGGACATGT GGCCAATGCCACTGAAGAACAATTTTTAAGAGTATTTATTTTTAATTGAATAAAATTTGA ATTTAAATAGCCACATGTGGATAGTGGCTACCAGATTGGACAGCAGAGCTCCCAACTTTA AAATTACAGTTCAATTTCAACTCAGTATAATGGGGTTCAATGTAACTGAGTAAAATAATT GGATGGTTGAATTTACCCACAGCAGCATACAGAAATATTCACTGATAAATCAGAACTCTG TAGACCTTTCTCACACTCATTTTATATTGTGTTTGGTTGTGAGTTACATGATTGCTGCAG GCACCATATTTATTTCTGTGCTCCAGGTCTCTAAAGGTCCTAATCCAGTCCTGACCAAAC AGACTAGTGATGGACCATCGTGAGCTTCTCTCAGGAGAAATATCAAGAGGGAGGCCAACC TGTAATCATAAGAACTTCTGCTATTTTAATGCCATTCATCAGACTACAGTCAATCACCAT GCTTCTGGCTTTTTGTCTATCTCTGCTGTCTTGTACATCCTGAGATAGTCCATTCTGAGA ACTGTACCCTAGATCTTGTATTGCCTGATGCCTGTCAAAGATGTAATCCATGCTGCTTAA GTGAGGTTGTGCACACAAATCACCATATCTCCTGCAAGTTTGGATTTTGATTCAGTAGTT CGATGGTGGGGTTTGAGATTCTGCATTTCTAATAAGCTCCCAGATGTGGCTGGTGCTGCT GGTCCATGAAACACACTTTGAGTAGCAAGAGGTGATCTGTAGCTCAGTATTGGTCCTTTA AGTTCCCTCAAACATATATAGAGAAAAGGTCCTAAATATTGCAAATTCTCTCAAAGTTTG TCAAGCTATATTGGAATTCTCTCAAAGTCTGTCAAGCTCTATTGTAGAAAATCAAATTTT TATTGGGAAAAAGCCTACCCCATATTTACTTACAGATAAAGTACTTTTAGGATCATTCAA GGCACACACCCATAACACTGAGTATGTAAGACAGAAATGCTCTCTCTGGAAATTACAGCA GTGCTGGTGCTGGGATGCCATGATGAGGAGTGTGTGGCCCACAATCATGTAGACCTTGGG AAAACCTGGATTAAAATGATTTTGCGTCATCCTGGCCCTGTATAAGATACATATCAGAAT GAAAACCACTCCCAGTGTGACTTTGAATTGCTTTTCCATTTTTTCTTCTTGGGATTAGAG AGCTTCACTTAGATTTCATCTAAGCTGTGATGTTGTACGTTGACCTGATTTACCTAAAAT GTCTTTCCTCTCCTTTCAGCTCTGTCTGATCTGGAGCTCGCAGCCCAGTCAATAATCTTC ATTTTTGCTGGCTATGAAACCACCAGCAGTGTTCTTTCCTTCACTTTATATGAACTGGCC ACTCACCCTGATGTCCAGCAGAAACTGCAAAAGGAGATTGATGCAGTTTTGCCCAATAAG GTGAGGGGATGACCCCTGGAGATGAAGGGAAGAGGTGAAGCCTTAGCAAAAATGCCTCCT CACCACTCCCCAGGAGAATTTTTATAAAAAGCATAATCACTGATTCCTTCACTGACATAA TGTAGGAAGCCTCTGAGGAGAAAAACAAAGGGAGAAACATAGAGAACGGTTGCTACTGGC AGAAGCATAAGATCTTTGTACAATATTGCTGGCCCTGGTTCACCTGTTTACTGTTATCAC AATAATGCTAAGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGGAGTGTGGCGAGAAG ATGGCCAAACAGGAACAGCTCCAGTCTACAGCTCCCAGCGTGAGCAACACAGAAGACGAA TGATTTCTGCATTTCCAACTGAGGTACCGGGTGCATCTCAATGGGGATTGTTGGAGAGTG GGTGCAGGACAGTGGGTGCAGTGCACCCAGCCTGAGCCAAAGCAGGGCGAGGCATCACCT CACCTGGGAAGTGCAAGGGGTCAGGGAATTCCCTTTCCTAGGGGTGACGGACAGCACCTG GAAAATCAGGTCACTCCCACCCTAATACTGCGCTTTTCTGATGGTCTTAGCAAACGGCAC ACCAGGAGATTATATCCCGCGCATGGCTCGGAGGGTCCTACGCCCATGGAGCCTCGCTCA TTGCTAGCACAGCAGTCTGAGATCGAACTGCAAGGCAGCAGCAAGGCTGGGGGAGGGGCG CCCGCCATTGCTAAGGCTTGAGTAGGTAAACAAAGCTGCCAGGAAGCTCAAACTGGGTGA AGCCCACCGCAGCTCAAGGAGGTCTGCCTGCCTCTGTAGACTCCACCTCTAGGGGCAGAG CATAGCCAACCAAAAGGCAGCAGAAACCTCTGCAGACTTAAATGTCCCTGTCTGACAGCT TTGAAGAGAGTAGTGGTTCTCCCAGCACACAGCTGGAGATCTGAGAACAGACAGACTGCC TCCTCAAGTGGGTCCCTGACCCCCGAGCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGC AGACTGACACCTCACACGGCCGGGTACTCCTCTGAGACAAAACTTCCAGAGGAATGATCA GGCAGCAGCATTTGCGGGTCACCAATACCGCTGTTCTGCAGCCTCCACTCCTGATACCCA GGCAAACAGGGTCTGGAGTGGACCTCCGGCAAACTCCAACAGACCTGCAGCTGAGGATCC TGACTGTCAGAAGGAAAACTAACAAACAGAAAGGACATCCACACCAAAACCCATCTGTAC ATCACCATCATCAAAGATCAAAGGTAGATAAAAACACAAAGATGGGGGAAAAACAGCAGA AAAACTGAAAAATCTAAAAATCAGAGCACCTCTCCTCCTCCAAAGGAACGCAGCTCCGCA CCAGCAACGGAAAGCTGGATGGAGAATGACTTTGACGAGTTGAGAGAAGAAGGCTTCAGA CGATCAAACTACTCCGAGCTAAAGGAGGAAGTTCGAACCCATGGCAAAGAAGTTAAAAAC CTTGAAAAAAGATTAGACAAATGGCTAACTAGAATAATCAATGCAGAGAAGTCCTTAAAG GACCTGATGGAGCTGAAGACCATGGCACGAGAACTACGTGATGAATGCACAAGCCTCAGT AGCCAATTCAATCAACTGGAAGAAAGGGTATCAGTGATGGAAGATCAAATGAATGAAATG AAGAAAGAAGAGAAGTTTAGAAGAAAAAGAATAAAAAGAAAGGAACAAAGCCTCCAAGAA ATATGGGACTATGTGAAAAGACCAAATCTACGTCTGATTGGTGTACCTGAAAGTGACGGG GAGAATAGAACGAAGTTGGAAAACACTCTGCAGGATATTATCCAGGAGAACTTCCCCAAT CTAGCAAGGCAGGCCAACATTCAAATTCAGGAAATACAGAGAACGCCACAAAGATACTCC TCGAGAAGAGCAACTCCAAGACACATAATTGTCAGATTCACCAAAGTTGAAATGAAGGAA AAAATGTTAAGGGCAGCCAGAGAGAAAGGTCGGGTTACCCACAAACACAAACCCATCAGA CTAACAGTGGATCTCTCGGCAGAAACTCTACAAGCCAGTAGAGAGTGGGGGCCAATATTC AACATTCTTAAAGAAAAGAATTTTCAACCCAGAATTTCATTTCCAGCCAAACTAAGCTTC ATAAGTGAAGGAGAAATAAAATACTTTACAGACAAGCAAATGCTGAGAGATTTTGTCACC ACCAGGCCTGCCCTAAAAGAGCTCTTGAAGGAAGCACTAAACATGGAAAGGAACAACTGG TACCAGCCACTGCAAAAACATGCCAAATTGTAAAGACCATCGAGGCTAAGGAGAAACTGC ATCAACTAACGAGCAAAATAATCAGCTAACATCATAATGACAGGATCAAATTCACATATA AAAATATTAACCTTAAATGTAAACGGGCTAAATGCTCCAATTAAAAGACACAGACTGGCA AACTGGATAGAGTCAAGACCCATCGGTGTGCTGTATTCAGGAAACCCATCTCACGTGCAA AGTAACACATAGGCTCAAAATAAAGGGATGGAGGAAGATCTACCAAGCAAATGGACAACA AAAAAAGGCAGGGGTTGCAATCCTACTCTCTGATAAAACAGGCTTTAAACCAACAAAGAT CAAAAGAGACAAAGAAGGCCATTACATAATGGTAAAGGGATCAATTCAACAAGAAGAGCT AACTATCCTAAATATATATGCACCCAATACAGGAGCACCCAGATTCATGAAGCAAGTCTT TAGAGACTTACAAAGAGAGTTAGACTCCCACACAATAATAATGGAAGACTTTAACACCAC ACTGTCAACACTAGACAGATCAACAGGACAGAAAGTTAAGAAGGATATCCAGGAATTGAA CTCAGCTCTGCACAAAGTGGACATAATAGACATCTACAGAACTCTCCACCCCAAATCAAC AGAATATACATTCTTTTCAGCACCACACCACACCTATTCCAAAATTAACCACATAGTTGG AAGTAAAGCACTCCTCAGCAAATGTAAAAGAACAGACATTATAACAAACTGTCTCTCAGA CCACAGTGCAATCAAACTAGAACTCAGGATTCAGAAACTCACTCAAAACCGCTCAACTAC ATGGAAACTGAACAACCTGCTCCTGAATGACTACTGGGTACATAACGAAATGAAGGCAGA AATAAAGATGTTCTTTGAAACCAACAAGAACAAAGACACAACATACCAGAATCTCTGGGC CACATTCAAAGCAATGTGTAGAGGGAAATTTATAGCACTAAATGCCTACAAGAGAAAGCA GGAAAGATCTAACATTGACACCCTAACATCACAATGAAAAGAACTAGAGAAGCAGGAGCA AACACATTCAAAAGATAGCAGAAGGCAAGAAATAACTAAGATCAGAGCAGAACTGAAGGA AACAGAGACACAAAAAAACCCTTCAAAAAAATCAATGAATCCAGGAGCTGGTTTTTTGAA AAGATCAACAAAATTGATAGAATGCTAGCAAGACTAATAAAGAAGAAAAGAGAGAAGAAT CAAATAGATGCAATAAAAATGATAAAGGGGATATCACCACCCATCCCACAGAAATACAAA CTACCATCAGAGAATACTATAAACACCTCTATGCAAATAAACTAGAAAATCTAGAAGAAA TGGATAAATTCCTCGACACATACACTCTCCCAAGACTAAACCAGGAAGAAGTTGAAACTC TGAATAGACCAATAACAGGTTCTGAAATTGAGGCAATAATTAATAGCTTACCAACCAAAA AAAGTCCAGGACCAGATGGATTCACCGCCGAATTCTACCAGAGGTACAAGGAGGACCTGG TACCATTCTTTCTGAAACTATTCCAATCAATAGAAAAAGAGGGAATCCTCCCTAACTCAT TTTATGAGGCCAGCATCATCCTGATACCAAAGCCTGGCAGAGACACAACCAAAAAAGAGA ATTTTAGACCAATATCCCTGATGAACAGTGATACAAAAATCCTCAATAAAATACTGGCAA ACCGAATCCAGCAGCACATCAAAAAGCTTATCCACCATGATCAAGTGGGCTTCATCCCTG GGATGCAAGGCTGGTTCAACATACGCAAATCAATAAACATAATCCAGCATATAAACAGAA CCAACGACAAAACCCACATGATTATCTCAATAGATGCAGAAAAGGCCTTTAACAAAATTC AACAGCCCTTCATGCTAAAAACTCTGAATAAATTAGGTATTGATGGAACCTATCTCAAAA TAATAAGAGCAAATTTATGACAAACCCACAGCCAATATCATACTGAATGGACAAAAACTG GAATCATTCCCTTTGAAAACTGGCACAAGACAGGGATGCCCTCTCTCACCACTCCTATTC AACATAGTGTTGGAAGTTCTGGCCAGGGCAATCAGGCAAGAGAAAGAAATAAAGGGTATT CAATTAGGAAAAGAGGAAGTCAAATTGTCCCTGTTTGCAGATGACATGATTGTATATCTA GAAAACCCCATCGTCTCAGCCCAAAATCTCCTTAAGCTGATAAACAACTTCAGCAAAGTA TCAGGATACAAAATCAATGTGCAAAAATCACAAATATTCTTATACACCAATAACAGACAA ACAGAGAGCCAAATCATGAGTGAACTCCCATTCACAATTGCTTCAAAGACAATAAAATAC CTAGGAATTCAACTTACAAGGGATGTGAAGGACCTCTTCAAGGAGAATTACAAACCACTG CTCAATGAAATAAAAGAAGATACAAACAAATGGAACAACATTCCATGCTCATGGGTAGGA AGAATCAATATCATGAAAATGGCCATACTGCCCAAGGTAATTTATAGATTCAGTGCCATC GCCATCAAGCTACCAATGACTTTCTTCACAGAACTGGAAAAAACTACTTTAAAGTTCATA TGGAACCAAAAAAGAGCCCGCATTGCCAAGTCAATCCTAAGCCAAAAGAACAAAGCCGGA GGCATCATGCTACCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGG TACTGGTACCAAAACAGAGATATTGATCAATGGAGCAGAACAGAGCCCTGAGAAAGAATG CCACATATCTACAACCATCTGATCTTTGACAAACCTGACAAAAACAAGCAGTGGGGAAAG GATTCCCTATTTAATAAATGGTGCTGGGAAAACTGGCTAGCCATATATAGAAAGCTGAAA CTGGATCCCTTCCTTACACCTTATACAAAAATTAATTCAAGATGGATTAAAGACTTACAT GTTAGACCTAAAACCATAAAAACCCTAGAAGAAAACCTAGGCAATATCATTCAATACAGA GGCATGGGCAAGGACTTCATGTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATT GACAAATGGGATCTAATGAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTACCATCAGA GTGAACAGGCAACCGACAGAATGGGAGAAAATTTTTGCAACCTACTCATCTGACAAAGGG CTAATATCCAGAATCTACAATGATCTCAAACAAATTTACAAGAAAAAAACACAACCCCAT CAACAAGTGGGGGAAGGATATGAACAGACACTTCTCAAAAGACATTTATGCAGCCAATAG ACACATGAAAAAATGTTCATCATCACTGGCCATCAAAGAAATGCAAATCAAAACCACAAT GAGATACCATCTCACGCCAGTTAGAATGGCGATCATTAAAAAGTCAGGAAACAACAGGTG CTGGAGAGGATGTGGAGAAAACAGGAACACTTTTACACTGTTGGTGGGACTGTAAACTAG TTCAACCATTGTGGAAGTCAGTGTGGTGATTCCTCAGGGATCTAGAACTAGAAATACCAT TTGACCCAGCCATCCCATTACTGGGTATATACCCAAAGGATTATAAATCATCCTGCTATA AACACACATGCACACTTATGTTTATTGCAGCACTATTCACAATAGCAAAGACTTGGAACC AACCCAAATGTCCAATAATGATAGACTGGATTAAGAAAATGTGGCACATATACACCATGG AATGCTATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAGAGACATGGATGAAGC TGGAAACCATCATTCTCAGCAAACTATGGCAAGGACAAAAAACCAAACACTGTATGTTCT CACTCGTAGGTGGGAATTGAACAATGAGAACACATGGACACAGGAAGGGGAATATCACAC ACTGGGGCCTGTTTTGGGGTGGGAGGAGTGGGGAGGGATAGCATTAGGAGATATACCGAA TGTTAAATGACGAGTTAATGGGTGCAGCACACCAACATGGCATAGGTATACATATGTAAC AAACCTGCACGTTGTGTACATGTACCCTAAAACTTAAAGTATAAAAAAAAAAATTCAAAA ACCTCAGTGGCATCTAATGAGAAGCATTTATTGCTCACAAGACTGGATAGTGAGTTCTGC TGATACTGACTGGACTCACTCTGGTCTGGCTATGGTCTGAGGTAGCCTGGCCCTGGGGGC GCGATGGAGGCTGACTCAGCTCTCCCCACACCTGTCTCATGTTCCAGTCAGGTAGCCACT GGCCAAGAAGCCAAGCTAGGAACCAGGGTATCTGACTCCTGAGCTAAACTCTAACCCTCT ACAATACTGCCTCCCAAATATAACACCAAGTGCTAGGTACATATCATCCACAGTTTTCAG ACTTCTGCCCAAACTGGGATTCTTTTTAGTGTGAAGAGACCTGGCCTGTGGGGCTGACCC TGGTGTGGCTGTGAGGCAGACACAAAGGGACATTTACATCCAGTCCTGAAGATTACAGTC CAGCCCTGAAGCAACAACTAGGAAACTATTCCAAAAGGAGGGGATGGGGCTGAGTGTGGG GTTCTATTCTCTTCATAACTTTAACTAGAACTCAAATTGTGTACCTTGGTAGCATCCAAT CATAAATTTATTTTGTCGTATTTGTGATAGAAAGGAACAAGTTTATCCACAAATTTATTT ATTTATTTATTTATTTATTTATTTATTTGAGACAGGGTCTGACTCTACGACCCAAGCTGG AGGGCAGTGGTGCAATCTCAGCTCACTGCAAACTCTGCCTCCCAGGCTCAAGCCATCCTC CCGCCTCTGTCTCCTGAGTAGCTGGAACTACAGGCACACGCCACCACACCCAGCTAGTTT TTGTATTTTTTGTAGAGATGGGTTTTCACCATGTTTCCCAAGCTGGTCTCAAACTCCTCA AAAGAGTTACCAAGCAGGACTCTGCAACCAATAATCCTTGTGTGAAGAGGATATTTGCTC TTTTCCCTGTTTTTCTTTCTTGGTACAGATGTGTGACCTCTTTTTGAAAGGTGATAGTGA CTTTGGTGTATTTTATTTGGTGGTAATGGTCATAGCCCCATTAATCACATTTCTTCCCAT GAGAAAGAAAAACCACTACATGGTCATGCTAAGGATTTCAGTCCCTGGGGTGAGGATGGT CTTGAATATCTCCTACATTCATAACTCCTCCACACATCTCAGTAGGTCACTGAGCACATC AATGGACATGCCAGTTATTAAAATACTTCACGAATACTATGATCATTTACCAGTATGAGT TATTCTCTGGAGCTTCTAATACTTCAATAGTACTGCATGGACTCAGTTGAGAGTTAATTC AAAATCTCAGATTATCCAATTCTGTTTCTTTCCTTCCAGGCACCACCTACCTATGATGCC GTGGTACAGATGGAGTACCTTGACATGGTGGTGAATGAAACACTCAGATTATTCCCAGTT GCTATTAGACTTGAGAGGACTTGCAAGAAAGATGTTGAAATCAATGGGGTATTCATTCCC AAAGGGTCAATGGTGGTGATTCCAACTTATGCTCTTCACCATGACCCAAAGTACTGGACA GAGCCTGAGGAGTTCCGCCCTGAAAGGTACAAGTCTCCAGGGAAATGGAGCTCACCCTGA CCCAGGCTGGTTCAAGCATATTCTGCCTCTCTTAATCTACATGACAATCGTGTGGTTGTA CAATCATTTGCTTGTAAGTCTTTTTATCACAAAAAAGTGATAATTATCAAACTTTACAAA CCACAGACTAGAAAAAACGAAACTACATCCATCCACAGTCCCAGCACAAGACAAAGATAA TCAATTATGTCCCTGTGGGCATTTTTCTACGCCTATATAGATTTTTAAAAATTAGAATGG TATCACTTTTTATTTGGTTTGAATTGCTGCTTACTTGATTTAACAGGAAACTATCCACTG ACCTATATTACTATAAATATACATATATATGTATATATATAAATATATATATATGTATAT ATTGCATATGCCATAAACCATTTAACCATGATGTTATTTCAGGTGTATAGGCTTTTTATT CCTTTCTGTTTTTTCTATGCTGTGCCCTTTAGCTCTCTGAATTTAACAGAAACTTTAAAA CATGCTTCCACATTCCATTTGCTTTCAACGTTACTTGCTATTTCCTCTGTAGTAATTATA AGAGTGCAGGCTGAGGTCCTGAGAAGTCCTCATCCCTAATGGTTTAAGCCACTTCACTGA AGACACAAGACAGCACAGGTCCTCCTGGTCCTATCTGTGGCTGCAGTCCTGTGCCAGCTC CCTTATACTCTCAGTAGACATCTCACACACTCCTCCTTGGAGGTGTCTTGAGCATGCTCT TCTGGGAATTCAGGGACAAGGTCAGGCCTTAGGCACAGTTCGCACTCTGGATATAGTTGG TGTTTTCCCATTACTGTATTATTAAGCAAAATTTAGAATGAAATTTTTAGGGTACTGGCT GGTGATTCAGGATGCTTGGGATCTAGACTTTCATTAGCCCCTACCTGCAAGTTTGCTGAT GGGAGGAACCTTGTCTTGTTGGTCATGGTGTCCCTAGTGCTAGCATGGAGTCTGCACATA ATACTTGTTCACAGAGTAAGTCAGAGCTGACCAAGTTCTCTGTTTTCTGGAGTAGAGGAC TTCTATGTTTCCTGCAAGCTCAGCACTTCCACCTCCTGTGGCTGCACTAATACGAAATCA GAGACCACTCGCTGTACTTCACTTTGAATCACTCAGTCACCAAAAAGATAGTGCTTGCCA TGTGTCAGGAACTTGGCTAGGCAGGGAGAAATTCATATGATTTATATAAATCCATAAATC CATATGATTTACATAAATCCATAAATTCATGTGATATATACGTATATGTGTGTGTATATA TATATTAGAGAATGTTTGACATATACACAAGTACATGTTACCGACACCAGCCTATAGAAT AGTTTTCGTGCATCTCCATATATCTATCACTGGTTCCAACAGCCATCAATCCATGTTAGC TGCCCCATCCAAATGCCACCATCACCCTCCTCCTGACTATCATGTTATTTTGAAGCAATA GCCTGTAAATATTTCAGAATGCTCTCCAAAATATAAAGACTCCTGTAAAAACATATGACA ACAATGCCATTATTACTTTCTTTGAATCAACATTTTTTCCTTAATATAATCAAATATTTA GAAATCAAATTTGAATAAAACATGGGTCAATCTTCAAAGAATTTATAGCTTAATGGAACA GATCAAGGAAAGCAGGGATGACACTACAGTAGGGTAGCATCATATGCCCATGTAACTTAT GTGACTTAAACTATCCTGTAAGGGTGTGGGGGAGAAAGAGAGGAAGAGATGGAGAGAAGA AAAAGGAAGAGAAGGAGGAGGAGAAGGAGGCAGAGGAGAAGGTGGACGGGGAAGGTAGAG AGGAGGAGGAGGGGAATTAGAAAAAAAGAGATGACAGGAGAAGGAAAGGGAAAAATAACA ACTTGAAATAGCACAAGACGTTTTCTCCTTCTCCTTTCTCAATGAGCATGTGACCAACAC AAGTGTGAGTTGAGGCAGGAATCCACTTTTCCATCCATCAGTCTTATCATTTATGTGCCT TTTATAGTGTGAACACATCACCACCCTGAATATAATTTTAGTGTTTAGAGATAAATATTA TTTGCAACAATATTCATCTCATCTCAAGAAACGCTCCTATAGGGTATGGAGAATTTAAAG GACCTGTAGGTTATGATGATTATAACGAAATAACCAAAGCAGGATTTCAATGACCAGCCC ACAAAAGTATCCTGTGTACTACTGGTTGGGAGGTGGAGGGGGGTTGTTCTTAAGTAAGAA CCCCTAACATGTAACTCTGTGGTTTTTATGTTTCATTAACTATTTAATCTACCAATATGG AACTAGGTTCAGTAAGAAGAAGGACAGCATAGATCCTTACATATACACACCCTTTGGAAC TGGACCCAGAAACTGCATTGGCATGAGGTTTGCTCTCATGAACATGAAACTTGCTCTAAT CAGAGTCCTTCAGAACTTCTCCTTCAAACCTTGTAAAGAAACACAGGTCAGTACACTTTC TGTATGTTTTATTAAGAATTTTTTTAACTGAAGGGTATATATTTTTTAAAAGAATATGCA TGTTTATCTTTTAATAATTCATTCTATGGGCCAAAGAACCTACTTGGATCCATCTTTGAT CATTAAGGATGCTTCAGTTCTGGACTTCAAAACCTGTAGCATTAAGAACATCATGTAAAG TCCACACAGATTAGCATGACATGATTATGTGTAGTCTCTTTGAACCTGAGTAAGTTTAAA TTCAGTTTCAAGTCAATTGGAAAGAAGTGTTTTGCACAATCATGAAGTGCAATGATTACC TGGCTGTGACTTAAATGGTGTTCTCCATCACCAGAACCTGCAGAAGCTCTCTCATGACAG TGGTTCTCAACCACTAGCTGTATATTGGAATCACCAGGGAGCTTCAAAAATTCATGATGC CTGTGACATCTCAGAAATTCTAAACTAATTAACCCAGAGCGTGACTAGGTTCTGTCATGC TGTCGGGTGAACCCCTGATTAGTTCTCACGTGAAGCCAAGGTGGAGAATGACTAATTTCA GGCATTTCTGGTGGATATGAAGGACTACCATAGAGCAGGGCTATCCTTACTCCTTGACCT TATGTTCCAGGTGATACATTTAAAGAAAGATTTAGAATCTTTTCTCTGAAGAAGTTAAAG AACAGATGTCATTGATTCATATTAAGCAATAGCCTATAAGTCTTATTTCCAGGACCGGTG TATTTAATATGCAACTCTACCCCTTAAGTACACTTTGTGCTTGGGAGAGGAGGAGGATGG AGATGGTTGCCATCTTATCTATGGCTTCAGGGCAGCTGTGTAGCTTTCCTATGTGTGTAT TCAGGCAGGGGGCTCAGCCCTGAGAGAAAGTGGGCCTCTGGCACACCTGGGACAGGGAAG ATATTCCCTGGCAAGCTCTCAGGCATCTCAGGCTGGCACTTCTTTGTATCCATGGCAATT TGCTTTCCCCTCACTGAACTGAGATCAGAATGTTACTCTGTTGGTGGCTCCCCCAACAGT GAAGGGGTGACTCAGTGACAATAGTGCTAGAAGTATGAGTCAAAACACTGTACAACTTGA GAAATTCCCCGTTTGCACTACGCTTGGAAGCCAAGAGGAGATGTTAAAAAGAAAAGAATA ATTCTTTCTGAAGACATTTCCCATCATTGCACTTGATGGGTTCAACTGGGAAGGGTTACT AGACTCTGGAAGTTGAAAACTGCCCACATAATTAAACTGTACAACAGCTACTCAGGATTA CCTTGCAAGTTTTAACCTATAAAAATTTAACTTTATATAGCACTTCCAAAATAGTTTGCC ATAATACCTACTAATCTGGATTTAATTTTTAAAACTCATCCTTTTAACTTAAGATTTAAA TAAAAAAAAAAAAACACGAGTCCACAAGAATTTGTCTCAGGCCTGGCACAGAGTCAGTGC TCCATAAATATTTTGTTAAACGATGGATGGTGAGTGCTTTTACTATCCAGTATTTACCCA GCTTATAGATTAAGTATGAAGAGTTCAAGATACATGGTGTTAAGAGTCGTTTTTATATGC TTGCAAAGCATTTTTGTCATATTTTTTCTACTTTGCTTCCATCTTTTCTTCTTTCACTTC ATTTATTAATTCTCCATATGCTTGTTTAACTATTGTAGATCCCCTTGAAATTAGACACGC AAGGACTTCTTCAACCAGAAAAACCCATTGTTCTAAAGGTGGATTCAAGAGATGGAACCC TAAGTGGAGAATGAGTTATTCTAAGGATTTCTACTTTGGTCTTCAAGAAAGCTGTGCCCC AGAACACCAGAGATTTCAACTTAGTCAATAAAACCTTGAAATAAAGATGGGCTTAATCTA ATGTACTGC OMIM ID 605325