Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP7A1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1581 Official gene symbol CYP7A1 Full name cytochrome P450, family 7, subfamily A, polypeptide 1 Aliases ,CP7A,CYP7,CYPVII,MGC126826,MGC138389, Gene summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq] Location Chromosome: 8   Locus: 8q11-q12 Gene position 59412720 - 59402737  Map Viewer Gene orientation minus Gene size 9984 bp Gene sequence >CYP7A1:complement(11267138..11277121):Length=9984 TGGCATCCTTCCCTTTCTAATCAGAGATTTTCTTCCTCAGAGATTTTGGCCTAGATTTGC AAAATGATGACCACATCTTTGATTTGGGGGATTGCTATAGCAGCATGCTGTTGTCTATGG CTTATTCTTGGAATTAGGAGAAGGTAAGTAATGTTTTATCTTTAAATTGCTCTTTGATTC ATCCATTTAATTTTTTTACCTTCATTTTTATACAGTAAATTTGGTTTTCTATACTTACAC ATATTAGCATTATCTTCCTTATTTTTTAAATGAAAAATTTGATTTGAATTTTTAAAGTAA TATCTTTTTTACTATATCTCACAAGACATATGACAGCTTCCCTTTTTAGTATTGGCATAT ACCGATGGTAATATATAAATGTATATTGGTGTTAAACATAACTGACAGAAATTGTATAAG GTCTCTATGTACATTTATATGTGTATCTAAAGAGGAAGCCCAGATTAGTAAGGATACAAG TAGCAAGTGGGAATCTACAATGGAAAGGATTGCTTTCTCTCACATGGCTTCAATAGATAC TCTTGTTAAATAAATGTTCTCTTTTAAGCTCATTCTTGTGCATCGCATAGACTCAGCCTA AGCCTGAACAAGAGCATAGAGCCTGAGCTGATCATTCTATTACTGTTTTTAAATAAATGT TAATCAACTGTGGTGAATTGGGAAAGTTTGCTGAGTGTATGTGACATCGATTTCATTTAT TTACAACTGGTTCAAGAATGCAAGAAAAACAAATACAGTCAGATCCAGAACCATAGTTTA TTTAACTTCTAATTGGCTCAAGGAGTAATTGTGGGGAGGCATATAGATATTCTCTGCTAT GTCAATCTCAAAAAGAGAAAATAACCCTAACCATCTTTCAGCTTTGTAGATTGCTATGTG TTTTCTGCCTTTTGCAGTTTCTTTCAGGCCTGATAGTTTTTACTTTTAATTAAACTACTT ATCTTCAAACTAAGAAAAGAAAGGTAATTACTTTATACTGTATTATTCTATCAAGAGGTA CAGAAGTTTATGTTGGAAAATAAGTTTACATGTTCTAATAAAAACATTTTAAAGGAGCAC TGAATTACAATAGATGATTCCGTCAGTGTTTATCTTACTCAATTTCATTTTATAATAAGC TGATTTCTCACATGAGATTCTTCTTCTCTGAAACCATCCTTATAGAATATAATATAGATA TCTTTAAACTAGGAATATTTTCAAAACCTCAGTTCTGAAATCCTCCCTTATTCAGTGATC TGTGTCTTTAAAGAAAATAATCAAAAGAAACATTTTGAGATATTTAGAAAAATGATGCTT AGCAAAGTGATAAACACTAGAATGTAGTTTTGTTTCCGCACTGACAACAAGAATCTTGTT GGTCTTGTAAATCCTTTTGCCTGTATCACTGGGAAAAGTGATGAGCACATAGTAGACGGG TGCTTGTTGAATGTGTATATGGACGGATGCATGAATGGATGGATTTAGTAATCCTTTCCA CCAACATATCATGTTACTAGGTTAATATAACCTATTACTGTAGTAAAAGAGCAGGGCCCA TCCAACAAAAGAAATATCTATAAACTATAGGGTTTCAAAGTTTGAAGTCAGTGGGAAAAA TTTTAAAACCTGATGTAAGTAAAAACCCAAAACTGTAATCATCCATGTCTATCATACACT TGTGTCTGACAGGCAAACGGGTGAACCACCTCTAGAGAATGGATTAATTCCATACCTGGG CTGTGCTCTGCAATTTGGTGCCAATCCTCTTGAGTTCCTCAGAGCAAATCAAAGGAAACA TGGTCATGTTTTTACCTGCAAACTAATGGGAAAATATGTCCATTTCATCACAAATCCCTT GTCATACCATAAGGTGTTGTGCCACGGAAAATATTTTGATTGGAAAAAATTTCACTTTGC TACTTCTGCGAAGGTAAGCAGTTTTACATTTATATACCATTCTGTTTGTCTTCTACCTTT TTATGTGCTTGTCTATTTAGAAATTTTGATGTACTTAGATTTTATGATAAAGGTGTTGAA GAGAGTTATCCTTATGTGGAGATTCTTAGAAACATAAATAAATTATACGTAGCTTCTTAG TAATAATCATTTAGAAAGTCAAAATAGGTATAGATTTGTCATTTGTTGACGAGCTAATGA GGGTGAAATACAGATTAAATGCTCTACTGAGACAGGTGGCACTGTACGAATAAGATAGAT AAAAATTCATCACATCAGCAATGTCTATGCAAGAATGCAAGTGACGGAAACCTAACATTC AGCAGTTGTCTCACCACACTTGTGCCACACAGTGTTTCATTTTGATAAGGAATTGGCAAG ATATTTTAACATCATTTAGATGTAATAAAAGAAGATCTGTTACTGAGAAAAAAAACCAAT AACTACTTACTTACTGCAAATAAATATTAGCTTTGGTCTTTGTGACTAAGTAGCTTAAAG TTTGGTTAAAATACATCTACAGCTGGACACAATGGAACACACCTGTAGTCCCTGCTATTT GAGAGGCTGAGGCAGGAGGATCGCTTGAGTCCAGGAGTTTGAGGCTGCAGTGAGCTATCA TTGTGTCACTGCACTCCAGCCTGGGTGACAATGTGAGACCCCATCTCTAAAAGAAAAAGA AAAAGAAATCTACAAATAATATAAAAGATAACTAATGATTTTAAAACATTATCAATTAGT TTATGTGCAATAGCTGTAAATAAGTGCAGTAGCATAAGAAATAAGACATAGATGACTTGA GTGATCCAGGGGAGTGCCACTGAAGTTGGCTTTAAAGGAAAGGTACAGTTTGGTCATTTA TTTGTAAAGTGCTATGAACTTGTACAAGGGAAAGCCAATTTCCCGTGTTTACCAAGTAAG GAACTATGAAAGTATCTAATCCGTTTTTCAGTCATTTACTATGACTAGGTCAGGTTTAAC TTCTTTTTCTGCATGTTTTATTTGCTATCAGGCATTTGGGCACAGAAGCATTGACCCGAT GGATGGAAATACCACTGAAAACATAAACGACACTTTCATCAAAACCCTGCAGGGCCATGC CTTGAATTCCCTCACGGAAAGCATGATGGAAAACCTCCAACGTATCATGAGACCTCCAGT CTCCTCTAACTCAAAGACCGCTGCCTGGGTGACAGAAGGGATGTATTCTTTCTGCTACCG AGTGATGTTTGAAGCTGGGTATTTAACTATCTTTGGCAGAGATCTTACAAGGCGGGACAC ACAGAAAGCACATATTCTAAACAATCTTGACAACTTCAAGCAATTCGACAAAGTCTTTCC AGCCCTGGTAGCAGGCCTCCCCATTCACATGTTCAGGACTGCGCACAATGCCCGGGAGAA ACTGGCAGAGAGCTTGAGGCACGAGAACCTCCAAAAGAGGGAAAGCATCTCAGAACTGAT CAGCCTGCGCATGTTTCTCAATGACACTTTGTCCACCTTTGATGATCTGGAGAAGGCCAA GACACACCTCGTGGTCCTCTGGGCATCGCAAGCAAACACCATTCCAGCGACTTTCTGGAG TTTATTTCAAATGATTAGGTGACTAACGCCATATCCATTTCTTTTTTTTATTTTAGTAGA AAGTAGAAATTAAACCACTTTAACTTTAAGAAAAAAAGCCTCGTAGTACTTTATCATGCC GTCAATCAAGAACGTAGCACTAATGCATGTTAGTGTTTAACATATATGAGTTCATTCAGT CCGCAGAAAAACATAGGCAGCTATGGCTGGTAAAAGTGTTTTATAGAAACAAAGACAGTC CCAGAGAAAGAGATGTCACCCCAAGCCACGGAGCTTGTATGTGCTGGTGTTGGGTCAATT CAGGCTGCCTGGCCCAGAGCCCTTGCTCTTAACCCCATACTGTTCTTCACGACGCCAACT CCACTCCATAAATGCAGTTTTCATAATCATTAAATGTATTTAAGTGATTACTGATTTATG GACAACAATCAGGGCGGTGACTATGCCTTACTTATTTGTTCATTCACAGTTTGTTTTCAC TCAGTTAGGAATTGCTGTTCTTCTGTTTATTTGACCAACTATGAGAGCTATGAATCAATC ATAATCTATTATTATTGATAAGAGACTTAGCTAGGTTGTGCTTTTTAAAACTGTATGTAA CAGAAAAAAACTGTAATAACATATGTTTTACATAACATGATTTCTCTCCAAAGTGTTAAT CTTTTGGGAATTTGAAATTAGAATGGTCTATTGAATTATTCCAATTAAATTAGATATTTA GTATCATGTAGACACAAAATTGCTCCTCCATAGGATTGGGAATGCCAAATTTCTATTGAT GGCTGATGACTTTAGGTCTTATAAAATATTTTAAAACTTAATTTCAGATGTGAGAACTTA TTACTAATTTGTCACAAATGTTGACTATCTTCCAAAGTTATTACTTGAAAAAGCACATCC AGAATAAATTCACATATTTACAGCAGGCATACGCATCAATTTAACATCATAAAGGAAATT GTAGCCATATTTTATGATAGTCTTACAAATACTTATCAAACATTTTGAGACTCAACTTAC TGTAATTTTGTTATGTAGCTCCCTAGACATGTTTAATCCTTGTTAGAAACACTTATTTAT AAAAGCCCTGACCAGGCCGGGCGCAATGGCTCACGCCTGTAATCCCAGAACTTTGGGAGG CCGAGGCGGGCGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAAC CCCGTCTCTACTAAAAAACATACAAAAAATTAGCTGGGCGTGGTGGCGGGCGCCTGTAGT CCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCG GTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAA AATAAATAAATAAATAAATAAATAAAAATAAAATAAAAGCCCTCACCAAAGTTTAACTTT TATGTAGCAAAGTCCCATTTTTTAATTATTATTATTATTTTTTTTTTCGAGACAGAGTCT TGCTCTGTCACCAAGGCTGGAATGCAGTGGCACGATCATGGCTCACTGCAACCTCCACCT CCCGGGCTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGATCCCA CTGCCATGCCTGGCTGATTTTTGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTGGTCA GGCTGGTCTCAAACTCCTGACCTCATGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGA TTACAGGCGTGTGCCACCACGGCCGGCCGCAAGGTCATTTTAAGGCAACAATTCTTACTA ATATCCAAGGACATAAACCCAATTACAAATGGAGTAAATGCAAACAGGAATATCCCTTTC CCTCCTCCCCTGGTATCTTCACCATCTAGTTAAAAGAAGGGGGAAAGGCCTATTTGTTTG CAGATCTCAAAGTATGGAAAAAGTTTATTTTCTGTACATACATGTTTTCTCTTACCTTTT AATAGGAACCCAGAAGCAATGAAAGCAGCTACTGAAGAAGTGAAAAGAACATTAGAGAAT GCTGGTCAAAAAGTCAGCTTGGAAGGCAATCCTATTTGTTTGAGTCAAGCAGAACTGAAT GACCTGCCAGTATTAGGTGGGTATACTTGTTATGTTGAGTTTCATTTTCTATGTCCTACT ACTTTAACAATAATGACCAACATAAATTATATACTTACCGAATTCTAGGCATTAAACTAA ATATTTCATATGAGTTTTCTCGGTTAATCCTCACAACTGTCCTGTGACTTGGGACTGTTA CTATTTATTTGTACCAAGTGAGGAAACTGACACCTAGAGGTTAAGCTGCAGCCAGGGTAG AATCAAATACATCATTATGTGGCATCCTATTCTCTCAACTACCACCCTGCACTGCCACAC CATGTTTCTCATATTCCTCTTACCACTAATCTGATGGTTAATGGAAGCATATTAGTCATT TTCATAAAATAAAGGAGGGAAAAGAACCATTAAGAAACCACAGTTACCTGCATGGATTGA GTGATGGATTTGAAAGTGCTTTGATTTTTCTTTGTTCTGCTTTTCTATATTTTATGGAAC TATAACAATATGATATTTTTATTTTTATTTATTTATTTATTTTTGACAAAGTCTTGTTCT GTTGCCCAGGCTGGAGTGCAATGGCGCGATCTTGGCTTACTGCAACCTCTGCCTCCTGGG TTCAAGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTAGGATTACAGGTGCACGCCACCA CCCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGTCCAGACTGG TCTCGAACTCCTGACCTCAAGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTAC AGGCATGAGCCACCGCACCCGGCCAACAATATGATATGTTTATAGTAATAAAGTTTTCTT TTTTTGGTTATTTTCTTTAAGGAGGCAAGAAGCTTAGGTTCCATGCTGGGGCTGACTTGG GAGACTTTGGACATGTCAGTACTCTTTTGGGGGCCTTACTTTTCTTATCTGTAAAATAAA ATGCTAACATTCTGGAATTTTATACACAATCATGTGATGAGCACCCTAAAACATGACAGT TAAAGGATACGGCTAAAAGGTCAGGCTGGACCTCTCGCGAGCTCTCTATATTTCAGCCAT TTTCAGGTTGGTTCTTTTTGTCCCTTTATGCCTTTACCGGGCAGCGGTGATCGCCACGCA GCATCAGATAGTATATGGATAAAAATAGGTTCTTGTAAATGTTGAACTGAAGCTGCATTA AACACCTAGAAAAAACATATGTATGTGTCAGTGCTATCAGTATATTCAATCTCAGAAGTC CTCAGTATATTAAATCTCAGAAGTGATAAACTTTGAATAATTTCTATAAAAATGTATTAC TGATTTTTCCAGTTTTATTACATTACTCTTCTATAAAATGATGGAATTTTGTTTCCCAAT TATGACCAAGATGATTATCTCTTAATCAAAAGATTATTATTAACTCAGGATCAGATTTAA AGATACATTCAGGCCAGGCACGGTGACTCACACCTGTAATCAAAGCACTTTTGGAGGCTG AGATGGGCACATTGCTTAAGCCTAGGAGCTCAAGAGCAACCTGGGCAACATAGCAAAACC CTGTCTCTGCAAACAATAAAAAGAAGAAAATTAGCTGGGTATGGTGGCACATGCCTATAG TCGCAGCTACTCGAGAGGTTGAGGTGGGAGGATCAGTTCAGCCTGGGAGGTTGAGGCTGC AGTGAGCCAGGATCATGCCACTGCACTGCAGCATGGGCAACAGAATGAGACCCTGGCTAA AAAGAAAAACAAAAATAAAAAAATTCAGACACAGTTGAATCATTGATAACAGCATAGTGG TAACAGAAAGAAAGTTTGGGAAATTTTTATCTGATCAGCTTCCCATACCCTGTTCATCTT TGTGTTATGCACTGCCAGGCTGTCTGTAGTTCAGACTCTATATCATATGACCTTCAAACA CTTGGTTTGTTCTTCTCTTCCTTCCTCCCTTCCTTCTTTCATTTTTTATCTTTTTTTCTT TTAAAATGTTTAGATAGTATAATCAAGGAATCGCTGAGGCTTTCCAGTGCCTCCCTCAAC ATCCGGACAGCTAAGGAGGATTTCACTTTGCACCTTGAGGACGGTTCCTACAACATCCGA AAAGATGACATCATAGCTCTTTACCCACAGTTAATGCACTTAGATCCAGAAATCTACCCA GACCCTTTGGTAAGTGCCTGCCCATTGAAATTCAATATCCAGGTGATAGCTACCTAGATC TAAATAAAGAGGAAATTTACAATGGTAGAATTGATTTTATCATTGTAGTCACAGGAATTG TCTGCTTAATTGTGTTAAATATTCATATATTTTGGAAAATTTAGATAGTGGTCTGAATTT TTCATTTTAGTCCTGATATTTGCCATCACACAGTCTTTGCTAGATTATATTTGCAGTCAT GATAATAAACCTGCCACTTTTTTTTTCTTAAAAAGCACCTCCTCCCAAATCCAGGAAATT GGAGGCTAATATATTGATTATTCTAGTTTCTTCTGGGAACCCTTCTCTCTCTAGCTCTGC CTGACTAAGGAACTAATCGTTCAAGCAGGATAGGAGGTATCACAAGGCTTCCTTAGCTCA TTAAGCTCCTGTTCCTTATTACTTTCTGATTCAATGTGGAGTATTTGCTAAATCACTAAT GGGGTAGAATTAAAAAGAAAATTACTCTTTGGAGCTTCCAGGTTTAGAAAGAGATAAATT TCTTTAAAACTAGCTTAAAGGCGGTTTTCTTTGTATTTTTATTGCAGACTTTTAAATATG ATAGGTATCTTGATGAAAACGGGAAGACAAAGACTACCTTCTATTGTAATGGACTCAAGT TAAAGTATTACTACATGCCCTTTGGATCGGGAGCTACAATATGTCCTGGAAGATTGTTCG CTATCCACGAAATCAAGCAATTTTTGATTCTGATGCTTTCTTATTTTGAATTGGAGCTTA TAGAGGGCCAAGCTAAATGTCCACCTTTGGACCAGTCCCGGGCAGGCTTGGGCATTTTGC CGCCATTGAATGATATTGAATTTAAATATAAATTCAAGCATTTGTGAATACATGGCTGGA ATAAGAGGACACTAGATGATATTACAGGACTGCAGAACACCCTCACCACACAGTCCCTTT GGACAAATGCATTTAGTGGTGGTAGAAATGATTCACCAGGTCCAATGTTGTTCACCAGTG CTTGCTTGTGAATCTTAACATTTTGGTGACAGTTTCCAGATGCTATCACAGACTCTGCTA GTGAAAAGAACTAGTTTCTAGGAGCACAATAATTTGTTTTCATTTGTATAAGTCCATGAA TGTTCATATAGCCAGGGATTGAAGTTTATTATTTTCAAAGGAAAACACCTTTATTTTATT TTTTTTCAAAATGAAGATACACATTACAGCCAGGTGTGGTAGCAGGCACCTGTAGTCTTA GCTACTCGAGAGGCCAAAGAAGGAGGATGGCTTGAGCCCAGGAGTTCAAGACCAGCCTGG ACAGCTTAGTGAGATCCCGTCTCCGAAGAAAAGATATGTATTCTAATTGGCAGATTGTTT TTTCCTAAGGAAACTGCTTTATTTTTATAAAACTGCCTGACAATTATGAAAAAATGTTCA AATTCACGTTCTAGTGAAACTGCATTATTTGTTGACTAGATGGTGGGGTTCTTCGGGTGT GATCATATATCATAAAGGATATTTCAAATGATTATGATTAGTTATGTCTTTTAATAAAAA GGAAATATTTTTCAACTTCTTCTATATCCAAAATTCAGGGCTTTAAACATGATTATCTTG ATTTCCCAAAAACACTAAAGGTGGTTTTATTTTCCCTTCATGTTTTAACTTATTGTTGCT GAAAACTCTATGTCCGGCTTTAACTATCTTCTCTATATTTTTATTTCATTCACATTAATG AGAAGAGTTTTCTCAGAGATTAAAAAAGGTAGTTTTTCTGTCATTGTTAAATACACATTA TCACTGAAAAAATGTAGCTTTTATGTGATATGTTTTAAAGTTAAAACTGGATGGAAATAG CCATTTGGAAGCTTTGGTTATGAAACATGTGGAGTGTATTAAGTGCAGCTTGACATTATG TTTTATTTAAATGCTTTTTATCGCTAAATGACTTGCAGATGAAAAAAACTAAGGTGACTC GAGTGTTTAAATGCTGTGTACAACAATGCTTTGATAAAATATTTTAAGTATGAGTTATCA GCTCTATGTCAATTGATATTTCTGTGTAGTATTTATATTTAAATTATATTTACCTTTTTG CTTATTTTACAAATATTAAGAAAATATTCTAACATTTGATAATTTTGAAATGATTCATCT TTCAGAAATAAAAGTATGAATCTA OMIM ID 118455