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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP11B2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1585 Official gene symbol CYP11B2 Full name cytochrome P450, family 11, subfamily B, polypeptide 2 Aliases ,ALDOS,CPN2,CYP11B,CYP11BL,P-450C18,P450C18,P450aldo, Gene summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq] Location Chromosome: 8   Locus: 8q21-q22 Gene position 143999259 - 143991975  Map Viewer Gene orientation minus Gene size 7285 bp Gene sequence >CYP11B2:complement(57265524..57272808):Length=7285 GGAATGGCACTCAGGGCAAAGGCAGAGGTGTGCGTGGCAGCGCCCTGGCTGTCCCTGCAA AGGGCACGGGCACTGGGCACTAGAGCCGCTCGGGCCCCTAGGACGGTGCTGCCGTTTGAA GCCATGCCCCAGCATCCAGGCAACAGGTGGCTGAGGCTGCTGCAGATCTGGAGGGAGCAG GGTTATGAGCACCTGCACCTGGAGATGCACCAGACCTTCCAGGAGCTGGGGCCCATTTTC AGGTAAAGCCCTCCCTGGCCCTCGCTGGGAACACCCAGATCCCTGCCCCTGCTGCCCAGG ACCCTGCCAGGCACTCAGCACTGCCATTCCCAGCAGGTCCCGGCACTCTGCATCCTTTGG AGGATGGGGAAGGAGTGCAGCACATGCTGGTCTGTGGTGCTGCCAGGGCAGGGGATAGTG CAGAGAAAACCCCAGCTCACTGCAGAGAGGGCAGGACTCAGAAGCACTAAAGTTGAAAGG TTCCAGGGAGCCAGCAGGAGGGCTTTAGCTGTGAAGCCGCTAATCCAGGAGCAGGGAGGG TGGACAGGAGACACTTTGGATTGGGACTGCAGGGTGGGGCCACGAGGGACATGACCCCGT CCAGCAGGGCCTCCTGCTTGGCCCCACAGGTACAACTTGGGAGGACCACGCATGGTGTGT GTGATGCTGCCGGAGGATGTGGAGAAGCTGCAACAGGTGGACAGCCTGCATCCCTGCAGG ATGATCCTGGAGCCCTGGGTGGCCTACAGACAACATCGTGGGCACAAATGTGGCGTGTTC TTGTTGTAAGCGGCGAGTTGGGAGCTGAGAGCTGGGAGCAGGGTGGGCAGCCTGGGTGTA GGGGGGAGGCGAGAGAGGTAGGACCCAAAAGCACATCTGCCCTGGGCCCCTGTGGTGGGC AGTGAGGGTGAGCACCCGGCCCAGAGGACGGCCATCCTGTGGGGTCGCGTCTGCACTGTG GGTTGGGGAAGCAGGGCGGTGGTGGAGAAATGGGCACGGGCACCTCTGCAGAGAAGACGC AGAGCAATGAGCCCTTCTGTGTAGTGAGAACCCGCTCTGCACCAACCTCGGCGGCTGCTT TCTCTTGCGGTCTGGGGACTGTCCTTCCCATAGGTCAGAAAACTGAGGCCCTGAGAAGGG GACTTCCACTGGCCCAGGTCACAGGCTGAGTGCTGAGCCTGGTGTTCGCCGGGGCCACAG CCTCCCTCAGGGCGCTCAGGGTCCCTGCAGTCCTGGCAAACCTTCCTGATGGGGACAGTC CGGGGCAGGAGGCAGGTGGGGACGCAGGTGGCTGGTGGTTCCGTTGTTCTCAGAAGCAAG GCACAAGGTGGGGCGGTTGATGGCACTGGGGAGGATGTTTCCTGGCCCGTGGAGAGGGTG GCGCCTGGTCAGGTGGGCAGGGAGAGGCTGATGCTTGGAGTCGGTCACCTGCAGGGATGT TGTCATTAGGACGGGGGAAGGACTGGATGAGGATGTCACAGTGGTGACAGCCCCCACTCC ATGGTAGGAAGGGAACGCTATTGGGAATAGTGGGGTTTAGGTAAAAGGGCACCCGTGGGT CGGGGCCTTCACTGAGGCTGGCCTATAGATGACATCTGGGAGAGAGTCAGGACCCAGGAA GGCAGGTCCAGGAGGCTGGGTGCGCATAATGGAAGGAAGGGGAGCGCTCCTGTATGTGTG TGTGTCTTGCATCTGTGCACATGCTGTGTGTTTCTCTGTACCTGCATTTGCACATGTGTA GTGTGTGCACGTGTCTGTGTGTGAATGTATGTGTGGTGTGTGTGCACAAGTGTCTGTGTG TGTGCATGTGCAGGTGCCGGCATGGGTGTAGTGTTTGTGCACACATGCACATGCGTCTCT TCACACATGGTGTTGAGGTCTTGCATGGGCGCACGTGTGCATGTGCATCTTCTGCCTGTC ATCACTGTCAACAGCTCACAGCAGCCAGCTGGACATAAATAAAGGAGTTTTGCAGGAATG TGGCTGACAGGGGAAATTCCTCCCCACCATTCCCTGGGGGCATCCATGGAGCCCCCACGC ACTCTGGCTGTGGGTGAGGATGGCATGAAGCACAAAGCTTGGTTTCTGTCCTGCAGAAGA TATAGATGCTTCACAGAGACAGGCAGAGGCTGCTGCCCCAGAGGCACTGTGCCCAGGGCG GGGAAGGGTGGGGAGGAGAGGGCAGCCAGGGGCTCTCCCCTCAGGACACTGTGTGGGTGA GGTGGGCAAAGCTTGACAACAGGGGTCACCTCCTTTCTTGGAGAAAAGCCCTACCCTGTT ACTACAGGGAGGGCCCGCATGGGTGAGGTGGTGCCAGACTTGGGTCGCCAGGTCCCGGGA ATGACCTCAGTTACCCTGTCAGCACCTGTGGGCAGAAGCTACCATCTCATCCCTGCTTAG ACCTGAGTGGCCTTTGCCCAGCACCTGGAGGCCGCTCTGAGAAAAGGCTGCAGCTCGAAC ACAAACAGGCAGCTTCTACCAGGGCCCCCAGTCAGCTCCCTGCAGGCCGATTCCCCTTGG GGACAAGGAGGATGGGATACGGGTCAGGGCCTGTGTCTTGCTGGGGCGGCCTCACAAGCT CTGCCCTGGCCTCTGTAGGAATGGGCCTGAATGGCGCTTCAACCGATTGCGGCTGAACCC AGATGTGCTGTCGCCCAAGGCCGTGCAGAGGTTCCTCCCGATGGTGGATGCAGTGGCCAG GGACTTCTCCCAGGCCCTGAAGAAGAAGGTGCTGCAGAACGCCCGGGGGAGCCTGACCCT GGACGTCCAGCCCAGCATCTTCCACTACACCATAGAAGGTGTGGGCCATGCGGGAAGGTC CAGCCCCAGAGACCCTGGAGTGGCCAGGGATGGGGATGGAGGACTGAAGGGAGTGTGGGG AGGCAGCCAGGAGGCCTGGGGCTGCCTTGTGCTCAGCAGTGCATCCTCCCCGCAGCCAGC AACTTAGCTCTTTTTGGAGAGCGGCTGGGCCTGGTTGGCCACAGCCCCAGTTCTGCCAGC CTGAACTTCCTCCATGCCCTGGAGGTCATGTTCAAATCCACCGTCCAGCTCATGTTCATG CCCAGGAGCCTGTCTCGCTGGATCAGCCCCAAGGTGTGGAAGGAGCACTTTGAGGCCTGG GACTGCATCTTCCAGTACGGTGAGGCCAGGGACCCGGGCAGTGCTATGGGGAAGGGACAC CATGGGGGCCCAATTTCTCCTTCTCCACCACCCAGTGGGGAATGGAGGCCACAGGGAGGG GTCGGGGATTCCTCACCTTCCTGCCGGGGAGATTGGTGCGAGGCTGGGGCTGGGCTGGGC TGATCCGGAGAATTTGGGATGAGAGCAGGGAGATTTGGGTGTCGGGGCAGTCTGGGCAGG AGGAGGACACTGAAGGATGCTTCCCAGCACCAAGATCTGAGGGCTGTCCCCTGCTCCCTG GACAGGTGACAACTGTATCCAGAAAATCTACCAGGAACTGGCCTTCAACCGCCCTCAACA CTACACAGGCATCGTGGCGGAGCTCCTGTTGAAGGCGGAACTGTCACTAGAAGCCATCAA GGCCAACTCTATGGAACTCACTGCAGGGAGCGTGGACACGGTCAGGCCAGCAACCAGCCC CACCCAGAGAGGGTGATGCCAAGCCTGCCTCCCAGGCACTGCCTGCCAATGCCACACGGC ACCCACGTTCCCCATCCCCAGGCTACAGGCCCCACATTTCTGTTGCCCTCAGCCTTCCCC CTCCTTTGTTAAGGGATGAGATTTGCAGGGGAGGGGAAATGTGAGCTCCCCCTCACATGA GACTGAGTTTGCAGTTACCTGTGTGGGGATCCATGCTCCAGGCTGGAAGAAAGTTGGATG AGGCCCTGGACACACAGCAGCTCTGTCCCCACTGGAAAGCTCTGGGTGTACAAGGAGAAG GAGGGTTGAGAGGCAGCTGGAGGACTCCACTGGGCACCCTTCCCAGTGTGCCCGGTCACC TTGGGCCAGAAATGTAGATGCATGGGAGGGCAGGGTTGTGGGGAAGACAGCAGCACAGGC TCCAGCCAGTGCAGAGGGGCCTGTGGGTGCACAGTGGGGAGAACTCAATGGAAGCAGAGG GAGCTGGGGCTCCAGAACTCCCTGGATGATGCTGAGGTGTGGCCCCCTGCCCTAATGGTG GCTGTGAGAACCCGCCCTGAAGAGGCTGCAGGGGACCTGGGCCTTGGTGGAGATGGGGGT CACCTTTCCCTGAAGAAGTCAGGGAATCTGGCCCAAGTGGTCATCAAGGTTTCAGATCCG GGGTCCCAGGGCTCTGTTTTTGCTCAGGGCATGGATGTCTCCACCCCTCAGAGGGAGGTT GTCCTGGGAGGGGTGTCCCGGGGGCTGAGTCCTCCTGTGCAAGGTCTGACCCTGCAGACA TGGCTTCTGTAGACAGCGTTTCCCTTGCTGATGACGCTCTTTGAGCTGGCTCGGAACCCC GACGTGCAGCAGATCCTGCGCCAGGAGAGCCTGGCCGCCGCAGCCAGCATCAGTGAACAT CCCCAGAAGGCAACCACCGAGCTGCCCTTGCTGCGGGCGGCCCTCAAGGAGACCTTGCGG TGGGTGCTGGCTGAGGCCTCCCTGTGGCCCTGGCCCCCTGCTGGAGAGCAGCCCCCACTG GGTGGTGGCAGACAGAATCTGGGGCTGATAAACAGCGTCACCCAGCAGCCCATTCCCCTG CACCTGCTCTTCCTCCCCCTCAAGGACAGGGAGCTCTTCTTCCTCTGGAATCCCTCTTCA ACACCCTGGGGATTAACGTGGGGCATGTCCTTCTGCGCTTGGGGCTTCTCAAGTTAGGGG AGGTTTGGCTGGGCTCAGCAGGTGCAAGGAAGTACTTCCTACGACCTGGGCTTCCCATGG ATCTGGGACCTCTGCGGGGTCTTCGGTAGGAAGGGTGCAGAGAGCACAGGAAGCCCCATC CAGCTGAGGACCCTTTCTATGGATGCCCCCACCTCCAGGCTCTACCCTGTGGGTCTGTTT TTGGAGCGAGTGGTGAGCTCAGACTTGGTGCTTCAGAACTACCACATCCCAGCTGGGGTG AGTGAGCCCCACACCCCTCGAGCTGAGAACCTCCCTCCCCAGTCATTCCCTGATCCCTGC TCTGCACCGTCCGCAGACATTGGTACAGGTTTTCCTCTACTCGCTGGGTCGCAATGCCGC CTTGTTCCCGAGGCCTGAGCGGTATAATCCCCAGCGCTGGCTAGACATCAGGGGCTCCGG CAGGAACTTCCACCACGTGCCCTTTGGCTTTGGCATGCGCCAGTGCCTCGGGCGGCGCCT GGCAGAGGCAGAGATGCTGCTGCTGCTGCACCACGTAAGCAGGCCTGGGGGCGGGGGCGG GACCTGGGCAGCAGAGGCGGGACCTGCACACTGGGGGCGGGGCTTGCATGGTGTGATTGA CACCTGGGAACAGTGGATGGGGCCTTGGTTGGTTGAGGTCGGCGTGACCAGGGAGGATCT GTGCTGAGCAAGACAGGGTAGGATCTGGGTGAGGCTGCTTCTAAACATTGAAATGGGGAC TAGGGGAGTGGGGTGGAGCCTGTACAGAATAATGGGGCTTGGGCAAGACCTGGGCAGGAT TCAGTCTGGGCCTGGTCCGTAAGGTGGGGCTGGTCAGAAGTGGGATAGGTTGGGGCCCAG GCTGCTGCTCCCCCTTCAGCATAATTGTTGCACCTGGGACGATGGGAGGAAGCTGCCCCA GGTCCATGGGCTACTGACCAGGCCAGATGGAAACCCAGCCTCTGTCCTAGGTGCTGAAGC ACTTCCTGGTGGAGACACTAACTCAAGAGGACATAAAGATGGTCTACAGCTTCATATTGA GGCCTGGCACGTCCCCCCTCCTCACTTTCAGAGCGATTAACTAGTCTTGCATCTGCACCC AGGGTCCCAGCCTGGCCACCAGCTTCCCTCTGCCTGACCCCAGGCCACCTGTCTTCTCTC CCACGTGCACAGCTTCCTGAGTCACCCCTCTGTCCAGCCAGCTCCTGCACAAATGGAACT CCCCAGGGCCTCCAGGACTGGGGCTTGCCAGGCTTGTCAAATAGCAAGGCCAGGGCACAG CTGGAGACGATCTTGCTGGCAGGGCCTGGCCTTGTCCCCAGCTCCACCTGGCCCCTTCTC CAGCAAGCAGTGCCCTCTGGACAGCTTGACTCTACTCCCAGCGCTGGCTCCAGGCTCCTC ATGAGGCCATGCAAGGGTGCTGTGATTTTGTCCCTTGCCTTCCTGCCTAGTCTCACATGT CCCTGTCCCTCTCGCCCTGGCCAGGGCCTCTGTGCAGACAGTGTCAGAGTCATTAAGCGG GATCCCAGCATCTCAGAGTCCAGTCAAGTTCCCTCCTGCAGCCTGACCCCAGGCAGCTCG AGCATGCCCTGAGCTCTCTGAAAGTTGTCACCCTGGAATACGATCCTGCAGGGTAGACTA AAAAGGCCCCTGTGGTCACTTATCCTGACACATTTTCAAGTGATACAACTGAGTCTCGAG GGGCGTGTGTTCCCCAGCTGATCATGTCAGCCTCATGCCCCAGGCCTCGTCTTTCATGGA CCAGGTCTTGTTCAAGCAGCGAGTGTTGGGTCCTCTGCTTCCTGAGCTGTCCCCTGGAGA AGGTCCCGAGGATGCTGTCAGGAGATGGAAGAGTCATGTGGGGTGGGAACCTGGGGTGTG GTTCCAGAAATGTTTTTGGCAACAGGAGAGACAGGATTGGGCCAACAAGGACTCAGATGA GTTTTATTGACTCATTCCTCTGGTTGATACGGAGCCATGTCATGTGCCACGACCTGGGGT GGGCACAGGGAGGCTGCAGTTCCCTACGTGAACCTGCCTTGGGCCTCATCTGCTCCTAGC CCAGCAGAGAGAGTTGACCCCTCCTGAACTGGCCACTCCCCAGTGCTCCTGTGCAGGGAT AGGAAGTGCCCCAGGGTGAGAACGTGCCCAGCCACATCATCTTTATCTCCTGGGATTTTC ATTAGGGCAAAGATCTCAGCAGCCAGCTCCTGGTAGCTGATGAGGATCAGAGCGTTTGTT CCCCCATGAAAGGGGAAATACTTAGGTAATCATTCCAGGTGTGTTCAGTAGTTCCAGGAC TCAGGGACTCAGGCCAGTCACCCTGTGACCGCAGGTTGCTTTCCCACCCTGGGCAATGCA GTGCAGCATGGGAAAGGAATAAGGGGGCAACAAGGTGCACAGACCTCAGAGATGGCTTCC TTGTTTATGGGGCTCTCACAGATACCCATCCAACTCCTCTAGTCAGCACTAGATCATGGG ATCCTAAAATAAACCTTGGAAAAAT OMIM ID 124080