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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CYP17A1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 1586 Official gene symbol CYP17A1 Full name cytochrome P450, family 17, subfamily A, polypeptide 1 Aliases ,CPT7,CYP17,P450C17,S17AH, Gene summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq] Location Chromosome: 10   Locus: 10q24.3 Gene position 104597290 - 104590288  Map Viewer Gene orientation minus Gene size 7003 bp Gene sequence >CYP17A1:complement(55394752..55401754):Length=7003 ATATGAGCTCAGGCCTGGCTGGGCTCCAGGAGAATCTTTCCACAAGGCAAGAGATAACAC AAAGTCAAGGTGAAGATCAGGGTAGCCCTTTAAAAGGCCTCCTTGTGCCCTAGAGTTGCC ACAGCTCTTCTACTCCACTGCTGTCTATCTTGCCTGCCGGCACCCAGCCACCATGTGGGA GCTCGTGGCTCTCTTGCTGCTTACCCTAGCTTATTTGTTTTGGCCCAAGAGAAGGTGCCC TGGTGCCAAGTACCCCAAGAGCCTCCTGTCCCTGCCCCTGGTGGGCAGCCTGCCATTCCT CCCCAGACACGGCCATATGCATAACAACTTCTTCAAGCTGCAGAAAAAATATGGCCCCAT CTATTCGGTTCGTATGGGCACCAAGACTACAGTGATTGTCGGCCACCACCAGCTGGCCAA GGAGGTGCTTATTAAGAAGGGCAAGGACTTCTCTGGGCGGCCTCAAATGGTAAGTGGTGC CCATCTCCTCCCTGCCCCCTTCACCACCCCCTGGGATTGTTCAGGTCTTCAGACCATGCC TAGAATGGGGCTTCCAGCTCCAACAACCTGTAATTCTTCCCAAAGTAGACTAGTGGGATG ATGTGAAGGGAGTGAACCTTCAGACCCCCACCCAGCCTCTAAATTAGGCAGGAAGAATTA AAGGAATGTCTCCTCTACCAGGCTGCCCAGGAGGTGGGATGGGAGGACCACAGTGGTCTG AGGGGTCAAGGAATCCTCACTCCACTCCTCTCTCTGAGCCTAGACTTCTCTAATGGACTG AGAAGGTGCATGTACAGCACTTAGCCTAGCACCCAGCACAGTAAGTGCCCCTTATACAGC CAGGATTCATGTTACTTTTCATGGAAAATGGGGGCAGTGACTACTGTCCTCCATGAAAGC TGCTGGGGAGAATTAGCCTAGCTATTGCAGGCTGGGATTGCTGCTTTCCTGGTGCTATTT CCAGCTACTCAGGCTCACAGGGGCAGTTTTCTACAATGACATTTCAGGGTTGCTGATGAG CCTCCCACTCAGCAGGGCCCCCAGCCTCTCAGCATTTTTTTTTTTTTTTTTTTTTTTTGA GACAGAGTCTCTCTCTGTCGCCCAGCCTGGAGTGCAGTGGCCAATCTCAGCTCACTGCAA CCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTACCTGGGACTAC AGGAGCATGCCACCATGCCCGCTAATTTTTTGTATTTTTAGTAGAGATGGTGTTTCACCA TGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCTCCCACCTTAGCCTCCCAAA GTGCTAGGATTATAGGCGTAAGCCACTGTGCCCTGCCAGCCTCTCAGCTTTGATCAAGCC AAGGGTTGGTTTATTTTTTCTTGGACCAATCAGCCAGGTCTGCTGACCAACTACCTAGCT CCCACCTCTGCTGGCTTCCTCCCGGGGGCAGAGAAGATGGAGAAGGCTAGTCATGTGGAT CTTCAGGGTCAGGAAATGGAAAAGGGAGGCTTTGGACCCTTTTGCTTTGGGGGGCACCTC TAGGAGGAGGCGGCTCGGCCCAAGTCCAGACTGGGTAGACAAAACATCTGCACTCTCCAA ATGTGGGCTTGTGGCTGGGTATGCAGGCTTGCAATGGAAGGGTAAACCTGAGTGAGGTGA GCTGTGCCTTTAGCTCAGCTAAGGGCTCAGGGAAAAGCAGAGATCTGTGCAGTCCTCAGC CTCTACAAGCTCACCTGCTCCCTACCCTCTGGACAGGCATAGTTTAGAGAGTTTATCCCA TCCAGAGTTGCCTTCCTGTGGTCAGAAACTGATGAGCAAAAAGAAGCCCAGAGGGCACCC TGTCAGCGAAAAGAACCCCAATGCTGCTGCATTCTAATTAAGGGTTCTTTCTTTCTCCTT GATCTACTGTATTTCTGAAGGAATTGGGAGTAGGAGGCCTTAGGGTCTGTCCTACCAAGT CCTTGCAGTCATGGTGGAGTGCAGTGGGGCTGTGCCCACATGGGAGTCAGCATGCCAGGT ACCTGCCTTCTCCTCCAGGAAGGAAAGCAGGGACCAGAGGTGTAAGGGCAAGAGTGGGGT GGATGGTGTGAGATTCCTACAGCCTTGCCTGCTCTCTAAAGGCAACTCTAGACATCGCGT CCAACAACCGTAAGGGTATCGCCTTCGCTGACTCTGGCGCACACTGGCAGCTGCATCGAA GGCTGGCGATGGCCACCTTTGCCCTGTTCAAGGATGGCGATCAGAAGCTGGAGAAGATCA GTGAGTGCCAGGCTGGCCCCTGGGGCTGGGGCTGGATCCCACAGGAGCTGCTGGAGGGAG AGGAGGGTTGGGCAGGGGTAAGGGTTAGGACTAGAGCGCAATGCAGCCTTTTCTTGGCTA CTGCTGCCATCTAGTGGCCATCTGCTATCTGTCCCCCGCTCCTGTTAAGAGGCAACTGGT ACAGAGAGGGGGTAAGGGTGCTGATTCATTTCCCACCCTCATGCCCCCTCTCCCTTCAGT TTGTCAGGAAATCAGTACATTGTGTGATATGCTGGCCACCCACAACGGACAGTCCATAGA CATCTCCTTTCCTGTCTTCGTGGCGGTAACCAATGTCATCTCCTTGATCTGCTTCAATAC CTCCTACAAGAATGGGGACCCTGAGTTGAATGTCATACAGAATTACAATGAAGGCATCAT AGACAACCTGAGCAAAGACAGCCTGGTGGACCTAGTCCCCTGGTTGAAGGTGAGATGCTG CCAGCCCTGCCTTCAGGTTCTAGTAGACCCTGACATTGTCCCCAATCTTCCTTCCTTTTT ACTTCCCTGCTCCAGCCGCAATGACCCATCTTTTTCCTGATTACCTCCGCCACCTCTACC TCCTCTGCCACTTAAAACCTTTGCCATTTCTCTGCAGAGATAGATTTAGCCTTTTAATTA TGCACCTTAGTACTCCAGATAATGACCTTCATTTCTTTTCCAATTACCATGTGCCAGTAC TAAGCATTCTATACGCATTCATCGCTGAATTCCCCTTGGAAGTAGGTTTTATTATCCCCA TTGTGCAGGTGAGAAGCAGGCTTAGCGGGGTTAAGGAGCTTGTCTGAGCCTTCAGGCTCA TGTCTCTCTCACTCCTAAGGGCTGGACACATAGCAGAGTCAGCGCTTGATGTTTGATTGA ATGGGGAAGGAGAGGTGGAGACCACGCCCTCCTCCCTTGTTTAGAATTGTCTTCGTCGTC ATGATAAACCCGTTCTGTGTCCCCATCTTGCCTTCCATTCTGGCTGAAGGTCAGGGGTGG AGTAGGAACTTCCAGAGACAGAAAGCTAAGATCCGCCTCCAGGAGAGACTCTGGCAGCTG GAGAAGCAAAATGGAAGAAGGGTGGATTTAACATTTCTTTTTATTTCCCAGATTTTCCCC AACAAAACCCTGGAAAAATTAAAGAGCCATGTTAAAATACGAAATGATCTGCTGAATAAA ATACTTGAAAATTACAAGGTAGGTGATAGAGCAGAAGAGAATATGAGTTAGGCTAAAAGT AATCACAAGAGCAGGGTGGAGTCCATTCTACACACTGTAGAAGCTTCAAAACCAAGCAGA GAACCTGGCACATAGTAGGTGTACAATAAAAACTGACTTAAGGGCTGGGCGCGGTGGCTC ACGCCTGTAATCCCAACACTTTGGGAGGCCGAGGTGGGCAGATCAATTGAGGTCAGGAGT TCGAGATGAGCCTGGCCAATATGGTGAAACCCCGTCTGTACTAAAAATACAAAAACTAGG CCAGGCAAGATGGCTCACACCTGTAATCCCAACATTTTGGGAGGCCAAGGTGGGCAGATC ACCTGAGGTTGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAACTCTGTCTCTACTAA AAATACAAAATTAGCCGGGCACGGTGGCGCATGCCTATAATCCCAGCTATTTGGGAGGCT GAGGCAGGAGACTCACTTGAACCCGAGAAGCAGAGGTTGCAGTGAGCTGAGATCATGCCA TTGCACTCCAGCCTGGGCATTGCACCAAGATTCTGTCTCAAAAAAAAAAAAAAAACTGAC TCAAGGAGTTGGGATCGAAAAGTGAGGAACTGAAGAGGATCCTAGAAGAGACCTAACCTC TCCACCAAATTTAAAGAGGGCCCGGGGCTGCCTCCTACCTCCACAAGTTCGTAGGTCCTG CCCAGACTTGCTCTACTTCCAAGTGGAAGGAGCCTTGTTATCTCTAGTCAGGGACAGAAG TATGGCAGGAGTGTCACAGATGGGGCTCCTTCCTTATTAATGTCTCCCAACCTCACCCAA CCCAGGAGAAATTCCGGAGTGACTCTATCACCAACATGCTGGACACACTGATGCAAGCCA AGATGAACTCAGATAATGGCAATGCTGGCCCAGATCAAGACTCAGAGCTGCTTTCAGATA ACCACATTCTCACCACCATAGGGGACATCTTTGGGGCTGGCGTGGAGACCACCACCTCTG TGGTTAAATGGACCCTGGCCTTCCTGCTGCACAATCCTCAGGTGTGCTTCCCCCTCATTG ATCCTAGACCCCAGCCAGCCCAATCTCTGGGCTCCAGAGAAAGGGAGAGCCAATTCTCTC AGGCTTTCTGTGCAGGAAGACTAGGCCTGCCCTGCTCCTTACCCAAGCAGTAGTTGGCTT TGACCCCAGAGTAGAGCTGCCCCATCTTCTGGAAGCCGGGCCTGGGCCCCAGAGCCACTA CTGGGAAGGGACTGGACAGGCTCTTCTCGATGTCACAGTTGGATTCTTCTCTAAGCCCTT GCTTCTCCTGGGCTTACACACACTAGTCACCTCCAACCTACTCTGGTCTTCAGGTGAAGA AGAAGCTCTACGAGGAGATTGACCAGAATGTGGGTTTCAGCCGCACACCAACTATCAGTG ACCGTAACCGTCTCCTCCTGCTGGAGGCCACCATCCGAGAGGTGCTTCGCCTCAGGCCCG TGGCCCCTATGCTCATCCCCCACAAGGCCAACGTTGACTCCAGGTGTGCCTGCCCTCCCA GTGACATCTAGCCCCATGATGCATTCAACACTGCTTGCCAGCCCACCTGGCTCCCCCTAC CCCCGGCCCCTGCTGGCCAACCTAAAGTCAGTCAACCATCAACTACTAAAAATCATCCTG CCGGCCGGGCACGGTGGCTCACACCTGTCATCCCAACACTTTGGGAGGTCGAGGCGGGTG GATCATGAGGTCAGGGGTTCAAGACCAGCCTGACCAATATGGTGAAACCCCGTCTCTACT AAAAATACAAAAATTAGCCATGCATCGTGGCGCGTGCCTGTAGTCCCAGCTACTCAGGAG GCTGAGGCAGGAGAATCACTTGAACCAAGGCGGCGGAGGTTGCAGTGAGCCAAGATTGCA CCACTGCACTCCAGCCTGGGTGACAGAGCGGGACTCTGTCTCAAAATAAATAATTAATTA ATTAAATATAAAAATCATCCTGCCCCCAGCCCCGTGGCTCCATGTCTCTACCACCTACAG ACACGCATTGACTCATCCACAGATCTGCCTGACTTCCCAGAGGAGCTTCCTGCTGCCCTC AGAGACATGTGGTCTGGGATGAAAGGCTGGGAGCTCCATGTTCCAACCAGCTGCAGCACG CACATAACATGCGCTGCAGCTCCAAACGCACACCCACATACACTGCCAGACACCAAAGTC CACAGACACAGGTGTTCAGACAGAAGCGCCTGTTAGGAGGGAAGGGATGGAGAAGGGCTG GATTTAGGTTTGATCTGGCAGAAGCTGAGGAAAACATGAGTGAGTGGGAATGAGGGAGTA AAGGGCATTTTCCTCACGGCGGAAGAATGAGGGGGCATGAGGCTGAGCAAGGAAGGGAGT ACGAAGTCCCAGACCCACTTTTCCTCTTCCACTCTGGAGCAGCATCGGTGAGTTTGCTGT GGACAAGGGCACAGAAGTTATCATCAATCTGTGGGCGCTGCATCACAATGAGAAGGAGTG GCACCAGCCGGATCAGTTCATGCCTGGTGAGTCTGTCCTGTCCTGCGCCCTGGGCCACAC AGCGAGCCTGGACTCTGCTCCACCACCCCAGTACCCCTTCACCTCTGCCAAGCTTGCTGC TAGAAAACTCTTGGCTCCAACTATACGGACCTGTTGACACCCTCATCCTGCCATAGACTT ACCCAAACTCTTCACAGCTGGGTTTCCCACGCTCTTCTTCCAACCAACTGCAAATTCACC CTCCAAGAAGCCCTCTACGCCTCTGTCTGCCATTAAGTCTGTCCCTTCTCCCCTCGGATG GTGCTATTTTCATAGGTTAATTCCATCTCTTTTCCATCCTTCCTGAATATTTCATTTCCT CTGTGTCGTTAAGGGCTACCTGAAAGCAGGGCTGTATCTCTCCCCAGGCGGGGGTTCCCC CATAATAAGGCTACATCCTCAGATCAGGGTTCCCTGGGCAGGGCCATGTCTCCCCCTCAA CCAGGGCAGAACCATGCCTCTCCTCCCTCCTGCCCTAACCCCTGGCTGATGCCACTCCTT GCCTGCAGAGCGTTTCTTGAATCCAGCGGGGACCCAGCTCATCTCACCGTCAGTAAGCTA TTTGCCCTTCGGAGCAGGACCTCGCTCCTGTATAGGTGAGATCCTGGCCCGCCAGGAGCT CTTCCTCATCATGGCCTGGCTGCTGCAGAGGTTCGACCTGGAGGTGCCAGATGATGGGCA GCTGCCCTCCCTGGAAGGCATCCCCAAGGTGGTCTTTCTGATCGACTCTTTCAAAGTGAA GATCAAGGTGCGCCAGGCCTGGAGGGAAGCCCAGGCTGAGGGTAGCACCTAAAGGCTGTA ACTCACAGCCCCTGTCCACCCTATGTGGCCCCACAACACAGATTTAGAGATACAACCCCC CACCCTTCTCCGCCATTCTTCCCTACTCCCAACCCACTCTGCCTTCTTTTTCAGCTTGTG GCAATGCCAGTGATGTGCATAAACAGTTTTTTTTTTTCCATAA OMIM ID 609300