| Entrez gene ID | | 1591 |
|
| Official gene symbol | | CYP24A1 |
|
| Full name | | cytochrome P450, family 24, subfamily A, polypeptide 1 |
|
| Aliases | | ,CP24,CYP24,MGC126273,MGC126274,P450-CC24, |
|
| Gene summary | | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
|
| Location | | Chromosome: 20 Locus: 20q13 |
|
| Gene position | | 52790516 - 52769988 Map Viewer |
|
| Gene orientation | | minus |
|
| Gene size | | 20529 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 126065 |
|
|
|
