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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AARS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID16
Official gene symbolAARS
Full namealanyl-tRNA synthetase
Aliases,CMT2N,
Gene summaryThe human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q22
Gene position70323412 - 70286297  Map Viewer
Gene orientationminus
Gene size37116 bp
Gene sequence
OMIM ID601065