Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DAD1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1603
Official gene symbolDAD1
Full namedefender against cell death 1
Aliases,OST2,
Gene summaryDAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q11-q12
Gene position23058143 - 23033807  Map Viewer
Gene orientationminus
Gene size24337 bp
Gene sequence
OMIM ID600243