Entrez gene ID | | 1610 |
Official gene symbol | | DAO |
Full name | | D-amino-acid oxidase |
Aliases | | ,DAAO,DAMOX,MGC35381,OXDA, |
Gene summary | | This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24 |
Gene position | | 109273857 - 109294710 Map Viewer |
Gene orientation | | plus |
Gene size | | 20854 bp |
Gene sequence |
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OMIM ID | | 124050 |
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