Entrez gene ID | | 16197 |
Official gene symbol | | Il7r |
Full name | | interleukin 7 receptor |
Aliases | | CD127,IL-7Ralpha,MGC107557 |
Gene summary | | Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq] |
Location | | Chromosome: 15 Locus: 15 A1|15 4.6 cM |
Gene position | | 9459631 - 9435914 Map Viewer |
Gene orientation | | minus |
Gene size | | 23718 bp |
Gene sequence |
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